All Cardiometabolic disease articles
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Study finds significant health benefits from gut microbes transfer
A cohort of overweight teens who received fecal transfer eight years ago were found to have reduced risk for a series of metabolic changes which can lead to heart disease, stroke and diabetes, compared with the participants who received the placebo.
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Myocardial infarction may be an infectious disease
A pioneering study has demonstrated for the first time that myocardial infarction may be an infectious disease. This discovery challenges the conventional understanding of the pathogenesis of myocardial infarction and opens new avenues for treatment.
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Kidney fibrosis linked to molecule made by gut bacteria
A molecule made by bacteria in the gut can hitch a ride to the kidneys, where it sets off a chain reaction of inflammation, scarring and fibrosis — a serious complication of diabetes and a leading cause of kidney failure.
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Scientists find a microbial molecule that restores liver and gut health
Researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure. The treatment may offer a new, non-toxic way to prevent and treat non-alcoholic fatty liver disease (NAFLD).
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Investigating regional-specific gut microbial distribution: an uncharted territory in disease therapeutics
A new perspective highlights the critical role of region-specific gut microbial distribution across intestinal segments (e.g., duodenum, colon) in regulating host metabolism and immunity, challenging traditional fecal-centric approaches.
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Microbiome breakthrough: Gut bacterium may hold key to future treatments for widespread chronic diseases
Scientists have identified a common specific gut bacterial strain that may open the door to a new class of therapeutics. This bacterium produces two proteins that influence the body’s hormonal balance and affect weight, bone density, and blood sugar levels.
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Trapping gut bacteria’s hidden fuel improves blood sugar and liver health, study shows
Scientists have discovered a surprising new way to improve blood sugar levels and reduce liver damage: by trapping a little-known fuel made by gut bacteria before they wreak havoc on the body. It could open the door to new therapies to treat metabolic diseases.
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New research uncovers gut microbe-derived metabolites as potential therapy for obesity-related metabolic disorders
New research reveals that certain gut microbial byproducts may hold promise as a novel therapy for obesity-associated metabolic complications by restoring critical hormone-producing cells in the intestine.
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Beetroot juice lowers blood pressure in older people by changing oral microbiome
The blood pressure lowering effect of nitrate-rich beetroot juice in older people may be due to specific changes in their oral microbiome, according to the largest study of its kind.
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How does infection with respiratory syncytial virus affect the health of older adults?
Adults aged 65 and older hospitalized for RSV in Ontario experienced significantly higher rates of adverse outcomes such as longer length of hospital stay, transfer to intensive care, and 30-day mortality, compared with patients hospitalized with influenza, urinary tract infection, or fracture.
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A gut microbiota metabolite linked to atherosclerosis could revolutionize diagnosis and treatment
A new study has identified a gut microbiota–derived metabolite, imidazole propionate (ImP), that appears in the blood during the early stages of active atherosclerosis, showing promise as a new diagnostic tool and opening the door to personalized treatment strategies.
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Nighttime pistachio snacking may reshape gut microbiome in prediabetic adults
A new study has determined that nighttime pistachio consumption affects gut bacteria in adults with prediabetes. The potential therapeutic implications of the findings may prove significant for people who are working to improve their metabolic health.
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Tracking microbial rhythms reveals new target for treating metabolic diseases
Researchers harness the benefits of time-restricted feeding on the gut microbiome — with the ultimate goal of developing new therapies for obesity, diabetes and related diseases.
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Study indicates that severe forms of COVID-19 infection in children may increase cardiovascular disease risks
Scientists analysed blood samples from 147 children across different COVID-19 conditions and identified significant metabolic disruptions beyond the acute viral infection phase. These alterations affect how the body processes fats (triglycerides and cholesterol) critical to healthy heart structure.
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Gut fungi breakthrough: Novel fungus offers hope for metabolic diseases
Scientists have unveiled a gut fungus that could transform treatment for metabolic dysfunction-associated steatohepatitis (MASH). The fungus produces a compound that blocks CerS6, an enzyme responsible for producing ceramides, fat molecules linked to metabolic disorders.
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Intestinal bacteria influence aging of blood vessels
Researchers have shown for the first time that intestinal bacteria and their metabolites can accelerate the ageing of blood vessels and trigger cardiovascular disease.
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Heart rhythm disorder traced to bacterium lurking in our gums
A new study finds that a gum disease bacterium can slip into the bloodstream and infiltrate the heart. There, it drives scar tissue buildup—known as fibrosis—distorting the heart’s architecture, interfering with electrical signals, and raising the risk of atrial fibrillation (AFib).
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Long COVID may cause long-term changes in the heart and lungs and may lead to cardiac and pulmonary diseases
Patients suffering from long COVID may exhibit persistent inflammation in the heart and lungs for up to a year following SARS-CoV-2 infection, potentially placing them at elevated risk for future cardiac and pulmonary conditions.
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A symbiotic gut fungus wards off liver disease in mice
Researchers have found a new ally in the fight against a serious liver disease: a symbiotic gut-dwelling fungus that produces a molecule shown to be capable of reversing disease progression in mice.
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COVID-19 vaccinations are metabolically safe, research finds
New research confirms that multiple doses of COVID-19 vaccines do not cause significant metabolic changes, offering reassurance for those concerned about potential long-term side effects of vaccination.