All Cardiometabolic disease articles
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NewsDietary fiber supplement shows promise for fatty liver, with effects linked to gut microbiota
A study investigating the effects of prebiotic xylo-oligosaccharides (XOS) on fatty liver in humans suggest that the fiber supplement may reduce harmful metabolic byproducts in the gut and improve liver health. The composition of the gut microbiota prior to supplementation influences the benefits observed.
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NewsCohabitating people share about a quarter of their gut and oral microbiota
People who live together share more oral and gut microbes with each other than with other people in their communities, according to a study. Researchers also found a link between more transmissible microbes and health, particularly type 2 diabetes.
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NewsMetformin given during acute COVID-19 infection reduced risk of clinician-diagnosed long Covid by 50%
New findings from the ACTIV-6 randomized clinical trial provide important confirmation of prior clinical trial results that metformin, a widely available and inexpensive medication with an established safety record, reduced the risk of clinician-diagnosed long COVID when started during acute COVID-19 infection.
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NewsSugar-free diets may disrupt gut microbiome
Eliminating sugar from your diet may be more detrimental than previously thought, according to an animal study. Mice fed a sucrose-free diet developed impaired glucose control, insulin resistance, gut microbial imbalance, intestinal inflammation and fatty liver changes, despite having no significant differences in body weight compared with control mice.
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NewsGLP-1s may alleviate depression in mice through the microbiome
Some people taking GLP-1 drugs for diabetes and obesity experience mental health benefits. In a mouse model study, researchers report that these improvements appear to result from gut microbiome changes that lead to an abundance of a microbe strain known to have a favorable effect on neurons related to stress.
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NewsInfections are major ‘health hazard’ for people with diabetes
Infections should be considered a “health hazard” in people living with diabetes, with experts warning that current clinical guidelines fail to reflect a substantial but under-recognised burden of illness, hospitalisation and death. People living with type 1 diabetes, type 2 diabetes and prediabetes face higher risks of infection compared to those without diabetes.
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NewsMaternal infection: A critical driver of offspring cardiac dysfunction
A new study reveals that maternal infection causes severe metabolic disturbances within the offspring’s heart, most notably enriching differentially expressed genes in lipid, energy, and amino acid metabolism. The infection also heavily suppressed cardiac cell proliferation.
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NewsHeart health may have impacted the risk of severe COVID-19 infection during the pandemic
Adults with highest heart health scores at the beginning of the pandemic were nearly half as likely to be hospitalized or die from COVID-19 when compared to those with the lowest scores, according to new research.
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NewsNew clinical study shows pasteurized Akkermansia muciniphila MucT supports weight loss maintenance
A clinical trial demonstrates that supplementation with pasteurized Akkermansia muciniphila MucT® significantly improved weight loss maintenance in adults with overweight or obesity following an initial weight loss intervention.
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NewsResearchers link human molecular, microbial diversity with geography, ethnicity
Researchers at the Stanford School of Medicine have found that ethnicity and geography may influence human molecular makeup — from metabolism and immunity to gut microbiota and biological aging. The findings, which published in Cell on May 14, illuminate the complex interplay between genetics and the environment, ...
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NewsProbiotic Lactobacillus rhamnosus CMU-pb-7 shows promise in alleviating diabetic nephropathy via antioxidative pathway
Rats with diabetic nephropathy treated with the probiotic strain Lactobacillus rhamnosus CMU-pb-7 showed marked improvements in general condition and serum biochemical profiles, including significant reductions in cholesterol, triglycerides, blood urea nitrogen, and serum creatinine.
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NewsBody weight affects your gut microbiota
A new study demonstrates that there is a correlation between gut microbiota and body weight. Researchers also observed that having a high BMI is detrimental to gut microbiota.
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NewsGut microbiota plays a role in metabolic health after bariatric surgery
Changes in gut microbiota after bariatric surgery are strongly linked to altered metabolic health and sustained improvement in type 2 diabetes. A study shows changes in gut bacterial composition and function are associated with metabolic improvements, including insulin release and blood sugar control.
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NewsAssociation of changes in portal insulin with immunometabolism during and after hepatitis C virus infection
A new study aims to investigate the relationship between insulin, the gut-liver axis, and immunometabolic changes in patients with hepatitis C virus. Lower portal insulin during HCVi is associated with changes consistent with altered pancreatic insulin secretion and decreased hepatic insulin extraction.
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NewsCOVID-19 and severe heart attack increase mortality by 25% after one year, more than double pre-pandemic rates
Findings from the North American COVID-19 Myocardial Infarction (NACMI) registry demonstrate significantly higher one-year mortality rates in patients with COVID-19 and ST-elevation myocardial infarction (STEMI) compared to patients with STEMI alone.
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NewsIntestinal Candida albicans is associated with subclinical coronary atherosclerosis in metabolic dysfunction-associated steatotic liver disease with cirrhosis
Researchers have published the first report of gut fungal dysbiosis associated with the severity of metabolic dysfunction-associated steatotic liver disease and subclinical coronary atherosclerosis. An increased abundance of fecal C. albicans was observed in patients with cirrhosis and high SCA burden.
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NewsAs syphilis cases rise, study links infection with higher risk of stroke, heart attack and other serious cardiovascular problems
Adults with later-stage syphilis are more likely to develop major cardiovascular problems – including stroke, heart attack or aortic aneurysm – than similar patients without the infection. The increased risk is primarily found in those whose infection progressed longer than a year.
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NewsGut microbiome serves as key driver for bacterial infection outcomes for fatty liver disease
Researchers found that metabolic dysfunction–associated steatotic liver disease dramatically worsens outcomes following infection with Vibrio vulnificus, a potentially life-threatening foodborne bacterium commonly associated with seafood consumption.
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NewsLong COVID associated with increased risk of cardiovascular disease
People with long COVID are at increased risk of developing cardiovascular disease, according to a new study. Women with long COVID had just over twice the risk of receiving a cardiovascular diagnosis compared with women without long COVID. Men had approximately a third higher risk.
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NewsKorean live microbes survey finds less inflammation from consuming fermented foods
A new study that analyzed South Korean health data to determine whether live microbe intake from fermented foods like kimchi is associated with certain health indicators, found a link between increased consumption of live microbe-rich foods and lower systemic inflammation.