All efflux pumps articles
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NewsEvolving antibiotic resistance under pressure may lead to personalized treatment
A new study demonstrates the use of an experimental evolution approach to map genetic mutations in Acinetobacter baumannii treated with one of two uncommon antibiotics.
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NewsBiochemists search for cellular vulnerabilities in killer ‘superbugs’
Helen Zgurskaya and Valentin Rybenkov are leading a five-year, $5.3 million project funded by the National Institute of Allergy and Infectious Diseases to find new ways to deliver lifesaving drugs directly into resistant pathogens.
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NewsResearchers capture new antibiotic resistance mechanisms with trace amounts of DNA
Scientists have developed a method to isolate genes from amounts of microbial DNA so tiny that it would take 20,000 samples to weigh as much as a single grain of sugar.
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NewsGlobal action urgently needed to tackle antimicrobial resistance, experts warn
Scientists have called for urgent changes to the way new antibiotics are developed to address the growing problem of antimicrobial resistance (AMR). They outline the scientific, economic, and regulatory barriers that are slowing progress.
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NewsNew study reveals global warming accelerates antibiotic resistance in soils
A new international study has revealed that climate change is accelerating the rate of development and global abundances of antibiotic resistance bacteria in soils.
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NewsStudies probe how novel inhibitors can switch efflux pumps off in TB bacteria
Two new studies aim to both identify and understand how novel inhibitors can switch efflux pumps off in the bacteria Mycobacterium tuberculosis.
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NewsEfflux pumps conferring antibiotic resistance found in archaea for the first time
Scientists have discovered antibiotic resistance mechanisms called efflux pumps in archaea for the first time.
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NewsResearchers discover how to sabotage antibiotic-resistant ‘superbugs’
Scientists say they have learned how to sabotage a key piece of machinery that pathogens use to infect their host cells, and have developed a test to identify the next-generation drugs to target this vulnerable cellular machinery.
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NewsScientists discover rules for breaking into Pseudomonas
Researchers have found a way to get antibacterial drugs through the nearly impenetrable outer membrane of Pseudomonas aeruginosa, a bacterium that – once it infects a person – is notoriously difficult to treat.
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NewsElectrochemical energies yield insights into how bacteria may develop antibiotic tolerance
Researchers investigated variations in the electrochemical energies that power bacterial growth to understand how bacteria develop antibiotic tolerance without acquiring new genes or mutating existing ones.