All Escherichia coli articles
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Researcher developing electronic nose to detect foodborne illness
A researcher is working on developing an electronic nose (e-nose) to detect abnormalities from their version of the sniff test. The method would revolutionize food safety by relying on what the e-nose can detect rather than only the appearance of the food.
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Heme-based sulfide sensing in bacteria: a new target for antibiotics
Heme binding to a bacterial transcription factor is critical for hydrogen sulfide (H₂S) signaling, a new study reveals. Heme binding promotes the reaction of H₂S with the transcription factor, leading to structural changes that can regulate stress tolerance in bacteria.
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Biodegradable PET alternative bioproduced at unprecedented levels
The PET-alternative PDCA is biodegradable and has superior physical properties. A team of bioengineers has engineered E. coli bacteria to produce the compound from glucose at unprecedented levels and without byproducts — and opened up a realm of possibilities for the future of bioengineering.
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Unlocking how bacteria bounce back after antibiotics
A groundbreaking study has uncovered how Escherichia coli (E. coli) persister bacteria survive antibiotics by protecting their genetic instructions. The work offers new hope for tackling chronic, recurring infections.
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New sepsis diagnostic could reduce critical time to save patients
A new diagnostic method would confirm sepsis infections earlier, cutting critical hours in the “race against time” to save patients’ lives. The process uses a centrifuge to separate bacteria from blood cells, and automatic microscopy for detection.
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‘Controlled evolution’ dramatically boosts pDNA production for biomedical manufacturing
Researchers have controlled the evolution of E. coli bacteria in the lab in order to dramatically increase the amount of plasmid DNA (pDNA) these modified bacteria produce. pDNA is an essential – and expensive – ingredient in many gene therapies.
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New hydrogel-based treatment accelerates infected wound healing and balances skin microbiota
A novel ε-poly-L-lysine-loaded sodium-alginate/gelatin hydrogel (PSG15) has shown exceptional promise in accelerating the healing of infected wounds. The injectable hydrogel delivers antibacterial properties while regulating macrophage polarization and stabilizing the skin microbiota.
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Environmental antibiotic resistance unevenly addressed despite growing global risk, study finds
Antibiotic resistance in the environment is a growing and largely overlooked crisis receiving inconsistent attention, according to a new study. Worryingly few studies have explored how antibiotic resistance spreads in the air, oceans or green spaces.
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Small protein, big impact: Insights into how bacteria stabilize a key outer membrane complex
Researchers reveal that a remarkably small protein is essential for the maturation of a component of the lipopolysaccharide transport system.
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Lavender steps up as a natural preservative in skin-care emulsions
A new study shows that blends of lavender essential oil and hydrosol can replace synthetic preservatives in oil-in-water creams, cutting microbial counts by >99 % without irritating skin.
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Hospital superbugs that cause sepsis and meningitis could be hitching a ride on mobile phones
Hospital superbugs that cause sepsis and meningitis could be hitching a ride on mobile phones, allowing them to escape out of healthcare settings and into the community, according to research presented at MLS Future Forum earlier this year.
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Smart bandage with ‘plant power’ heals chronic wounds faster than market leaders
A multidisciplinary team has unveiled a next-generation wound dressing that behaves like a living leaf yet fights like a miniature pharmacy. It combines neomycin-grafted cellulose nonwovens with a polyvinyl alcohol/cellulose-nanofiber aerogel dyed with blueberry anthocyanins.
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Microbially synthesized bioplastic may solve marine plastic pollution problem
Researchers have demonstrated a new eco-friendly plastic that decomposes in deep ocean conditions. In a deep-sea experiment, the microbially synthesized poly(d-lactate-co-3-hydroxybutyrate) (LAHB) biodegraded, while conventional plastics persisted.
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Bacteriostatic activity and mechanism of minerals containing rubidium
A new paper on traditional Chinese medicine outlines the bacteriostatic activity and mechanism of minerals containing rubidium (MCR).
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Disease-causing bacteria can deal with stink as long as they get a meal
Bacteria that cause intestinal infections typically avoid a stinky chemical — one that can kill them at high enough concentrations — inside human intestines, but they may actually swim toward it when a hearty meal is the reward.
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AI finds hundreds of potential antibiotics in snake and spider venom
Researchers used a deep-learning system to sift through a database of more than 40 million venom encrypted peptides (VEPs). In a matter of hours, the algorithm flagged 386 compounds with the molecular hallmarks of next-generation antibiotics.
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Flightpath Biosciences licenses microbiome-sparing antibiotic developed at Illinois
Flightpath Biosciences, Inc., has licensed a class of antibiotics developed at the University of Illinois Urbana-Champaign. The original antibiotic agent, lolamicin, effectively treated bacterial infections in animal models of disease without wiping out beneficial gut microbes.
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Multiresistant intestinal bacteria: Displacement through food competition
Researchers made use of food competition to figure out how potentially dangerous multi-resistant bacteria could be effectively removed from the gut before reaching the bloodstream and causing serious problems.
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Green light activates this antibiotic only where it’s needed
To make a more efficient antibiotic treatment, researchers have modified penicillin so that it’s activated only by green light. In early tests, the approach precisely controlled bacterial growth and improved survival outcomes for infected insects.
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New study reveals global warming accelerates antibiotic resistance in soils
A new international study has revealed that climate change is accelerating the rate of development and global abundances of antibiotic resistance bacteria in soils.