All Escherichia coli articles
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WHO warns of widespread resistance to common antibiotics worldwide
One in six laboratory-confirmed bacterial infections causing common infections in people worldwide in 2023 were resistant to antibiotic treatments, according to a new World Health Organization (WHO) report.
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Revolutionizing bioplastics: a microbial platform for fully bio-based long-chain polyesters
Researchers have developed a scalable, end-to-end microbial process transforming plant oils into sustainable polyesters comparable to petroleum-based plastics.
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From glucose to gourmet: engineered bacteria churn out key food additive
Researchers used E. coli as the chassis to produce inosinic acid (IMP), a popular umami enhancer. By reprogramming the metabolic flux network of E. coli and introducing amino acid mutations in the key enzymes in the synthesis pathway, the yield was significantly increased.
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Chemobiological platform enables renewable conversion of sugars into core aromatic hydrocarbons of petroleum
Researchers have developed a chemobiological platform that converts renewable carbon sources such as glucose and glycerol into oxygenated precursors, which are deoxygenated in the same solvent system to yield benzene, toluene, ethylbenzene, and p-xylene (BTEX).
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Scientists uncover molecular mechanisms for bacterial lipid transport
Researchers have successfully applied cryo-electron microscopy (cryo-EM) to unveil the molecular structures of critical protein machines that transport lipids and maintain the outer membrane (OM) barrier of Gram-negative bacteria.
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‘Alarming’ rise in newborn babies with antibiotic-resistant infections, researchers find
Researchers are calling for an urgent overhaul of diagnostic and treatment guidelines for infections in newborn babies, after a study revealed frontline treatments for sepsis are no longer effective to treat the majority of bacterial infections.
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Deadly pathogens found in commercial raw cat foods
An analysis of commercial raw cat foods detected disease-causing microbes, including some that are resistant to antibiotics, creating risks for both pets and their owners, according to a new study.
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Super-resistant bacteria found in wild birds at a rehabilitation center in Brazil
Researchers have found antibiotic-resistant bacterial clones in wild birds at a rehabilitation center. The identified Escherichia coli clones have been found in community- and hospital-acquired human infections worldwide, and were present in the intestinal tracts of a vulture and an owl.
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Nanoparticles supercharge vinegar’s old-fashioned wound healing power
New research has resulted in the ability to boost the natural bacterial killing qualities of vinegar by adding antimicrobial nanoparticles made from carbon and cobalt.
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Researcher developing electronic nose to detect foodborne illness
A researcher is working on developing an electronic nose (e-nose) to detect abnormalities from their version of the sniff test. The method would revolutionize food safety by relying on what the e-nose can detect rather than only the appearance of the food.
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Heme-based sulfide sensing in bacteria: a new target for antibiotics
Heme binding to a bacterial transcription factor is critical for hydrogen sulfide (H₂S) signaling, a new study reveals. Heme binding promotes the reaction of H₂S with the transcription factor, leading to structural changes that can regulate stress tolerance in bacteria.
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Biodegradable PET alternative bioproduced at unprecedented levels
The PET-alternative PDCA is biodegradable and has superior physical properties. A team of bioengineers has engineered E. coli bacteria to produce the compound from glucose at unprecedented levels and without byproducts — and opened up a realm of possibilities for the future of bioengineering.
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Unlocking how bacteria bounce back after antibiotics
A groundbreaking study has uncovered how Escherichia coli (E. coli) persister bacteria survive antibiotics by protecting their genetic instructions. The work offers new hope for tackling chronic, recurring infections.
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New sepsis diagnostic could reduce critical time to save patients
A new diagnostic method would confirm sepsis infections earlier, cutting critical hours in the “race against time” to save patients’ lives. The process uses a centrifuge to separate bacteria from blood cells, and automatic microscopy for detection.
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‘Controlled evolution’ dramatically boosts pDNA production for biomedical manufacturing
Researchers have controlled the evolution of E. coli bacteria in the lab in order to dramatically increase the amount of plasmid DNA (pDNA) these modified bacteria produce. pDNA is an essential – and expensive – ingredient in many gene therapies.
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New hydrogel-based treatment accelerates infected wound healing and balances skin microbiota
A novel ε-poly-L-lysine-loaded sodium-alginate/gelatin hydrogel (PSG15) has shown exceptional promise in accelerating the healing of infected wounds. The injectable hydrogel delivers antibacterial properties while regulating macrophage polarization and stabilizing the skin microbiota.
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Environmental antibiotic resistance unevenly addressed despite growing global risk, study finds
Antibiotic resistance in the environment is a growing and largely overlooked crisis receiving inconsistent attention, according to a new study. Worryingly few studies have explored how antibiotic resistance spreads in the air, oceans or green spaces.
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Small protein, big impact: Insights into how bacteria stabilize a key outer membrane complex
Researchers reveal that a remarkably small protein is essential for the maturation of a component of the lipopolysaccharide transport system.
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Lavender steps up as a natural preservative in skin-care emulsions
A new study shows that blends of lavender essential oil and hydrosol can replace synthetic preservatives in oil-in-water creams, cutting microbial counts by >99 % without irritating skin.
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Hospital superbugs that cause sepsis and meningitis could be hitching a ride on mobile phones
Hospital superbugs that cause sepsis and meningitis could be hitching a ride on mobile phones, allowing them to escape out of healthcare settings and into the community, according to research presented at MLS Future Forum earlier this year.