All Gut-Brain Axis articles
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NewsGLP-1s may alleviate depression in mice through the microbiome
Some people taking GLP-1 drugs for diabetes and obesity experience mental health benefits. In a mouse model study, researchers report that these improvements appear to result from gut microbiome changes that lead to an abundance of a microbe strain known to have a favorable effect on neurons related to stress.
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NewsThe brain, emotions, and the gut: How culture, stress, and social life shape gut health
A new study indicates that gastrointestinal health is influenced not only by genes, diet, and gut bacteria, but also by culture, social relationships, economic status, and the way individuals function within society.
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NewsNew urine test for microbial metabolites offers simple way to screen for autism in children
Scientists have developed a new screening tool to test urine for 17 microbial metabolites in children ages 2 to 11 years. By measuring these compounds in urine, they discovered that they could distinguish children with autism from typically developing children in their study groups with high accuracy.
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NewsHead impacts associated with altered gut microbiome in football players
Non-concussive head impacts—hits to the head that don’t cause clinically detectable symptoms—are correlated with subsequent changes to the gut microbiome in a small sample of US collegiate football players, according to a new study.
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NewsFrom gut to brain: scientists engineer bacteria to treat severe liver-related brain dysfunction
In vivo studies showed that programmable “living medicines” could reduce brain toxins and prevent neurological symptoms of hepatic encephalopathy, offering distinct advantages over a widely prescribed antibiotic.
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NewsThe brain–gut health initiative: A pioneering effort in psychiatric research
Researchers analyze brain imaging data, microbiome profiles, and clinical assessments to identify biomarkers for precision mental healthcare. The Brain–Gut Health Initiative is an ongoing long-term clinical study designed to investigate how interactions between the brain and gut microbiome contribute to psychiatric disorders.
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NewsNew research reveals mechanisms behind coffee’s positive effects on the gut-brain axis
First of its kind research shows the potential role of coffee as a further intervention to promote positive gut health and its effects on the gut-brain axis. Coffee was found to positively affect perceived mood and stress levels in individuals taking part in this study.
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NewsStudy shows links between Alzheimer’s and gut health can lead to prevention
Researchers analysed more than 120 everyday factors, including diet, medical history, gut bacteria, and lifestyle, to identify which of them are most strongly associated with Alzheimer’s risk. People who had their appendix removed showed substantially elevated Alzheimer’s risk.
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NewsGut microbiome changes may signal Parkinson’s disease risk
Scientists have found that people with Parkinson’s disease have a distinctive makeup of gut microbes, as do healthy individuals who are genetically at risk of Parkinson’s disease. This could help to develop tests to reveal a person’s risk of developing Parkinson’s disease.
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NewsScientists probe how neurons sense bacteria in the gut
Neural interaction with bacteria, e.g. in the gut microbiome, has important effects on brains of animals from worms to people. A new study investigates how neurons sense bacteria by revealing, in nematodes, the bacterial signals that a key neuron detects.
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NewsScientists explore the bidirectional skin-brain axis: Mental health, dermatology-related quality of life, and the role of probiotics
Researchers investigating associations between mental health, dermatology-related quality of life (DLQI), and probiotic intake in 305 Brazilian adults found that women had significantly higher scores for anxiety, depression, and stress compared to men.
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NewsHow gut bacteria and acute stress are linked
Researchers have demonstrated for the first time that, in healthy adults, the diversity of gut bacteria and their capacity to produce certain metabolites are associated with the acute stress response - particularly stress reactivity.
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NewsAutism and ADHD: Epigenetic changes at birth associated with an infant’s microbiome and neurodevelopment
Epigenetic changes present at birth can impact how an infant’s gut microbiome develops during their first year. Researchers also identified specific epigenetic changes and gut microbes that were associated with signs of autism spectrum disorder (ASD) and ADHD when the children were three years old.
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NewsInfluence of antibiotic use on mental health during pregnancy
New research points to an association between antibiotic exposure and maternal psychological distress in early-to mid-pregnancy.
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NewsSimple blood test for gut bacteria metabolites could spot dementia years earlier
Scientists have discovered that subtle changes in the blood may reveal the earliest signs of cognitive decline long before symptoms become obvious.These changes are caused by chemicals produced by gut bacteria - reinforcing the idea that the gut–brain connection plays an important role in early memory changes.
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NewsGut microbiota and the gut–brain axis: Mechanisms and therapeutic hopes for brain diseases
A new study looks at the gut–brain axis (GBA), a sophisticated bidirectional communication network that integrates neural, immune, endocrine, and metabolic pathways to govern brain function and systemic homeostasis.
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NewsHigh-fat diets cause gut bacteria to enter brain, study finds
A new study, performed using mouse models, establishes that live bacteria from an imbalanced gut microbiome can enter the brain via the vagus nerve. The vagus nerve connects the brainstem to the heart, lungs, and major abdominal organs, including the stomach, intestines, liver and more.
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NewsThe gut can drive age-associated memory loss
Scientists have discovered that the aging gastrointestinal tract produces specific molecules that blunt the activity of a key gut-brain neuronal pathway, leading to age-related cognitive decline in mice.
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NewsWhen rats run, their gut bacteria rewrite the chemical conversation with the brain
A new study suggests that exercise stimulates a molecular link between gut bacteria and the brain. The research examined what happens to the gut microbiota, circulating metabolites, and hippocampal gene expression when rats are given free access to a running wheel for eight weeks.
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NewsStudy highlights gut–brain axis in pituitary tumor–related cognitive decline
Researchers conducted a prospective cross-sectional study to evaluate cognitive function in patients with pituitary neuroendocrine tumors and examine associations among tumor lineage, hormonal abnormalities, and gut microbiota composition.