All hepatitis B articles
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News
Scientists unveil hepatitis B virus core protein as a Rab-GAP suppressor driving liver disease progression
In liver cells under oxidative stress, HBV core protein (HBc) perturbs mitochondrial dynamics and prevents cellular recycling of damaged mitochondria, thereby driving liver disease progression, a new study finds.
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Tenofovir alafenamide treatment achieves positive results in Chinese chronic hepatitis B patients
A five-year treatment regime with tenofovir alafenamide achieves high rates of viral suppression, alanine aminotransferase normalization, and favorable bone and renal safety in Chinese chronic hepatitis B patients.
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Paclitaxel-induced immune dysfunction and activation of transcription factor AP-1 facilitate Hepatitis B virus replication
A study finds that Paclitaxel treatment directly promotes HBV replication and transcription, leading to HBV reactivation in HBV stable expression cell models, HBV natural infection cell models, and HBV transgenic mouse models.
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Changing relationship between viral replication and the severity of hepatic necroinflammatory damage in patients with chronic hepatitis B virus infection
This study aimed to clarify the relationship between HBV replication and hepatic inflammation during disease progression of chronic hepatitis B virus (HBV) infection.
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Mechanism of action of the hepatitis B and D virus cell entry inhibitor bulevirtide deciphered
An international research team has succeeded in deciphering the molecular structure of bulevirtide in complex with the HBV/HDV receptor NTCP at the molecular level.
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Viruses can cause multiple myeloma cancer, case study finds, offering hope for treatment
An unusual clinical case has led to the discovery that hepatitis B and C viruses are one of the causes of multiple myeloma, and that eliminating infection with antivirals is often the way to fight this type of cancer.
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Study reveals how the immune system fights to keep herpes at bay
A recent study, conducted using lab-engineered cells, unveils the precise maneuvers used by host and herpes simplex virus (HSV) in the fight for dominance of the cell.
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Monoclonal antibody shows promise for treating chronic hepatitis B and D infections
In a preclinical study, the potential of an engineered investigational human monoclonal antibody for the treatment of chronic hepatitis B and hepatitis D has been demonstrated.
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War in Ukraine pushes highly contagious infectious diseases to alarming levels
New research being presented at this year’s ECCMID reveals an extremely worrying picture of rising infectious disease cases and falling levels of childhood vaccination and case detection in Kharkiv, the scene of some of the most intense combat in 2022.