All Immunology articles – Page 34
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NewsScientists track pneumonia-causing bacteria as they infect the blood stream
A new study has shown various dissemination patterns can be adopted by Klebsiella pneumoniae that causes systemic infection, i.e. bacteremia.
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NewsCold sore discovery IDs unknown trigger for those annoying flare-ups
Scientists have a new target to prevent cold sores after researchers discovered an unexpected way that the herpes virus re-activates in the body. The finding could also have important implications for genital herpes caused by the same virus.
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NewsExperts recommend mAb protection against RSV as standard care for all infants
While RSV poses a serious threat to the health of infants and young children, prophylactic mAbs offer safe and effective protection for an entire season, according to international health organizations.
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NewsImmunity against seasonal H1N1 flu reduces bird flu severity in ferrets, study suggests
Pre-existing immunity against seasonal H1N1 flu might help explain why most reported human cases of H5N1 bird flu in the U.S. have not resulted in lethal outcomes, suggests a new study.
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NewsNew insights into how specific gut cells respond to bacterial toxins
Researchers have characterized a specific gut cell type, BEST4/CA7+ cells, with the ability to interact with immune cytokine interferon-γ (IFNγ), and its regulation in cellular electrolyte and water balance, in response to bacterial toxins.
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NewsBacteria consumed by immune cells become part of the cell
Immune cells that eat bacteria in the body don’t stash them in specialized compartments as once thought, but turn them into critical nutrients that build proteins, create energy and keep the cells alive, according to a new study.
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NewsStudy reveals how bacteria in microbiome medicine trigger tumor-killing cells
Microbiotica has presented new data on the mechanism of action of MB097, a clinical-stage drug candidate being developed as a co-therapy in combination with KEYTRUDA® (pembrolizumab) in patients with advanced melanoma.
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NewsNeutrophil-to-lymphocyte ratio and its correlation with tuberculosis infection
A new study reveals a significant negative correlation between neutrophil-to-lymphocyte ratio (NLR) and the risk of tuberculosis infection (TBI), particularly in males and individuals with hypertension.
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NewsHerpesviruses may contribute to Alzheimer’s disease via transposable elements
Researchers have outlined the pathway human herpes simplex virus-1 (HSV1) can use to contribute to Alzheimer’s disease in aging brains, and also share two FDA-approved, commercially available drugs that reverse this pathway in a laboratory setting.
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NewsAs dengue spreads, researchers discover a clue to fighting the virus
Children who experience multiple cases of dengue virus develop an army of dengue-fighting T cells, according to a new study. Most children who experienced two or more dengue infections showed very minor symptoms—or no symptoms at all—when they caught the virus again.
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NewsStudy uncovers porcine reproductive and respiratory syndrome virus’s impact on swine immunity
Scientists used single-cell RNA analysis to reveal key immune mechanisms in lungs of swine infected with PRRSV. They found higher numbers of protective anti-inflammatory M2-like macrophages (SPP1-CXCL14high) were observed in less virulent infections, suggesting a potential role in promoting lung healing.
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NewsStealth virus: Zika virus builds tunnels to covertly infect cells of the placenta
Researchers have discovered that Zika virus in the placenta builds underground tunnels, a series of tiny tubes called tunneling nanotubes, that facilitate the transfer of viral particles to neighboring uninfected cells.
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NewsPromising antibody may prove useful against deadly Ebola virus outbreaks
New research reveals the workings of a human antibody called mAb 3A6, which may prove to be an important component for Ebola virus therapeutics.
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NewsGroundbreaking study shows potential of new mRNA vaccine to help fight tuberculosis
A new vaccine that boosts immunity against tuberculosis (TB) has been shown to be effective in pioneering pre-clinical trials. The mRNA vaccine was successful in triggering an immune defence response that helped to reduce TB numbers in infected mice.
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NewsMachine learning framework can decipher immune system’s record of past infections
A novel machine learning framework can decipher an individual’s immune system’s record of past infections and diseases, providing a powerful tool with the potential for diagnosing autoimmune disorders, viral infections, and vaccine responses with precision.
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NewsResearchers ID key immune differences that make one West African ethnic group less susceptible to malaria
Researchers have uncovered how genetic and lifestyle factors influence immune responses to malaria in children from two large West African ethnic groups. Children showed key differences in immune cell activity offering greater protection.
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NewsFungal compound could help protect against influenza
A preclinical trial uncovers how beta-glucan, a compound found in all fungal cell wall, can ‘reprogram’ immune cells to prevent lung inflammation from influenza and lower the risk of death by the host immune responses.
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NewsMass polio vaccination campaign to continue in the Gaza Strip
The emergency polio outbreak response in the Gaza Strip is continuing, with a mass vaccination campaign scheduled from 22 to 26 February 2025. The novel oral polio vaccine type 2 (nOPV2) will be administered to over 591,000 children under 10 years of age.
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NewsScientists develop new natural killer cell strategy to target HIV
Scientists have successfully identified a new approach using natural killer (NK) cells to target and kill the HIV-positive cells that allow the virus to persist. They genetically modified NK cells to express CD64, a protein not normally expressed by NK cells.
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NewsEvolutionary tradeoffs: Research explores the role of iron levels in COVID-19 infections
Iron has been found to be essential to both human physiology and pathogen replication. The richer the iron availability, the more likely to be susceptible to infections, such as COVID-19. A balance of iron levels is thus critical for homeostasis and preventing pathogenic infections.