All Infectious Disease articles – Page 22
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NewsTB and HIV treatments are not enough for a full recovery
Existing treatments control TB and HIV, but the immune system does not revert to normal, helping explain why people living with HIV remain susceptible to infections and underscoring the need for immunotherapies.
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NewsWhy don’t antibiotic-making bacteria self-destruct?
Scientists discovered a promising new antibiotic in a soil sample. The molecule, lariocidin, is produced by the microbe Paenibacillus and shows broad activity against pathogenic bacteria. Now, the researchers report how Paenibacillus avoids harm by its own antibiotic.
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NewsWhen a virus releases the immune brake: New evidence on the onset of multiple sclerosis
A study investigating the links between Epstein-Barr virus and multiple sclerosis shows that EBV can interfere with the control of B cells. One viral protein mimics a crucial “approval” signal that B cells usually require from other immune cells. Self-reactive B cells can then survive even when they should be shut down.
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NewsResearch reveals hidden diversity of E. coli driving diabetic foot infections
New research has shed light on the diversity and characteristics of E. coli strains that drive diabetic foot infections, providing the first comprehensive genomic characterisation of E. coli strains isolated directly from diabetic foot ulcers across multiple continents.
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NewsNew mechanism links Epstein-Barr virus to MS
Scientists investigating the links between the Epstein-Barr virus and multiple sclerosis show that when the immune system fights EBV, certain T cells – which normally attack the virus – can also react to a protein in the brain called Anoctamin-2 (ANO2), a phenomenon called molecular mimicry.
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NewsBirding enthusiasts can help songbirds avoid salmonella epidemics
Biologists are developing a tool to predict when deadly salmonella outbreaks are likely to happen in wild songbird populations so that people can protect their feathered friends by taking down bird feeders at the right time.
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NewsGenetic risk factor and viral infection jointly contribute to MS
One of the leading triggers for multiple sclerosis (MS) is an infection with the Epstein-Barr virus. However, certain gene variants also play an important role. Researchers have shown that it is the molecular interaction between environmental and genetic risk factors that ultimately triggers the disease.
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NewsNew hypothesis links HPV E6 and SARS‑CoV‑2 spike proteins to reduced p53 activity
Scientists have proposed a hypothesis suggesting that virally encoded proteins such as HPV-E6 or SARS-COV-2 Spike may cooperate in suppressing host defenses including tumor suppressor mechanisms involving p53.
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NewsA gentler way to model deadly lung infections in old age
Researchers report a refined mouse model that successfully mimics chronic Pseudomonas aeruginosa lung infection in old age. The study introduces an agar bead-based delivery strategy that allows bacteria to persist in the lungs of aged mice without causing rapid death.
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NewsVaccine against foot-and-mouth disease could deliver $1.3 billion a year in global livestock benefits
A new foot-and-mouth disease vaccine is projected to deliver over $1.3 billion in annual benefits and transform global livestock resilience.
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NewsGut bacteria protect mice with influenza A from bacterial pneumonia, study finds
Select gut bacteria protect mice against post-influenza virus secondary bacterial pneumonia, according to a study which sought to define whether intestinal bacteria influenced some individuals’ vulnerability to secondary bacterial infections following primary respiratory viral infection.
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NewsCat disease challenges what scientists thought about coronaviruses
Researchers have uncovered new details about how a once-deadly coronavirus disease in cats spreads through the immune system. For years, the prevailing belief was that the virus behind feline infectious peritonitis infected just one type of immune cell.
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NewsResearcher reveals secrets of bacteria that can swim upstream
Rather than washing pathogens away, strong fluid currents act as “guide rails” that align bacteria and accelerate their upstream migration. They discovered that this creates a “two-way invasion” where pioneer cells reach the source within minutes, seeding colonies that spread threefold faster than in still water.
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NewsResearchers uncover the secret route of prostate infections
A research team has developed a “mini prostate” organoid model using adult stem cells. Using this model, the scientists could follow a bacterial prostatitis infection step by step under controlled conditions and identify exactly how the bacteria attack.
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NewsUK: COVID-19 vaccine hesitancy decreased over time, though mistrust persists among certain groups
Most COVID-19 vaccine hesitancy is rooted in concerns that can be addressed and effectively reduced over time, according to a new study following more than 1.1 million people in England between January 2021 and March 2022 during the COVID-19 pandemic.
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NewsClinical trial in Ethiopia targets the trachoma scourge
A new study documents the outcomes of an evaluation of fluorometholone as adjunctive medical therapy for trachomatous trichiasis surgery, part of an initiative to better prevent blindness and improve quality of life for those affected.
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NewsNew study finds higher hantavirus risk in drier, underdeveloped areas
In a recent study of the contiguous USA, researchers found that the risk of disease from hantavirus is higher in drier, underdeveloped geographic areas with more socioeconomic vulnerability and increased numbers of unique rodent species.
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NewsResearchers revive failing antibiotics with two-faced Janus nanoparticles
Researchers have restored the power of failing antibiotics by combining them with two-sided nanoparticles, ultra-small building blocks of materials less than 100 nanometers across. The nanoparticles showed a remarkable ability to compromise bacterial cell walls, leaving them vulnerable to attack.
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NewsHow Mtb safeguards itself from foreign DNA
Researchers have discovered how a key protein in the tuberculosis bacterium helps protect it from the influence of foreign DNA inserted into its genome. Understanding how this protein – called Lsr2 – functions could help develop drugs that target it, thereby aiding in the fight against TB.
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NewsNew test shows which antibiotics actually work
Drugs that act against bacteria are mainly assessed based on how well they inhibit bacterial growth under laboratory conditions. A critical factor is whether the active substances actually kill the pathogens in the body. Researchers have presented a new method for measuring how effectively antibiotics kill bacteria.