All Infectious Disease articles – Page 20
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Genomic data shows widespread mpox transmission in West Africa prior to 2022 global outbreak
Mpox was transmitted among humans in Nigeria for eight years before sparking the international outbreak in 2022. Using genomic tracing, the researchers estimate that the virus’s ancestor first emerged in southern Nigeria in August 2014.
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Novel molecular maneuver helps malaria parasite dodge the immune system
Researchers have discovered how a parasite that causes malaria when transmitted through a mosquito bite can hide from the body’s immune system. Plasmodium falciparum can shut down a key set of genes, rendering itself “immunologically invisible.”
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Family of parasite proteins presents new potential malaria treatment target
Researchers from the Francis Crick Institute and the Gulbenkian Institute for Molecular Medicine (GIMM) have shown that the evolution of a family of exported proteins in the malaria-causing parasite Plasmodium falciparum enabled it to infect humans. Source: Ernst Hempelmann Ring stage of Plasmodium falciparum in human red blood ...
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Americans say benefits of MMR vaccine for children outweigh risks by nearly 5-1
While many Americans know how measles can spread, most cannot accurately estimate the prevalence of complications associated with measles such as hospitalization or the risks it presents during pregnancy, according to a new survey.
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New treatment targets link between viral infection and Alzheimer’s disease
A unique mechanism triggering Alzheimer’s disease draws attention: viral infection—while ALT001 is confirmed to alleviate neuroinflammation and suppress viral replication.
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The Global Fund to fight AIDS, Tuberculosis and Malaria ‘should step up efforts’
The international community must protect global responses to HIV, tuberculosis (TB), and malaria to serve humanity’s collective interests, according to a new opinion article.
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Proof of concept for HIV vaccination that deploys germline-targeting
For a preventative HIV-vaccine to work it should induce broadly neutralising antibodies against all the diverse strains of the virus. The first in-human assessment of germline-targeting strategy with a trimer displays positive results.
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Yellow fever vaccination: how strong immune responses are triggered
Researchers have shown how specific immune cells are activated by the vaccine – an important starting point for the development of new vaccines.
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New hope against superbugs: Promising antibiotic candidate discovered
An international team of researchers has discovered saarvienin A, a new type of glycopeptide antibiotic. Their findings introduce a compound with strong activity against highly resistant bacterial strains.
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Scientists evaluate in-vitro activity of ceftazidime-avibactam against carbapenem-resistant gram-negative bacteria
Scientists explored the in-vitro activity of ceftazidime-avibactam (CAZ-AVI) in clinical isolates of carbapenem-resistant gram-negative bacteria collected at the outpatient, emergency, and inpatient departments of the Indus Hospital, Karachi.
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New study offers insights into designing safe, effective nasal vaccines
Researchers found that nasal vaccine boosters can trigger strong immune defenses in the respiratory tract, even without the help of immune-boosting ingredients known as adjuvants. The findings, researchers suggest, may offer critical insights into developing safer, more effective nasal vaccines in the future.
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New discovery explains why men are more affected by severe COVID-19
Researchers have found another piece of the puzzle that explains why there are differences in immune responses in women and men when they get sick with COVID-19. This discovery has implications for treatment strategies for severe COVID-19.
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Measles virus detected in Houston wastewater before cases were reported
An innovative outbreak detection program that tracks disease-causing viruses in wastewater identified the measles virus in Houston samples collected in early January 2025, before cases were reported.
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New vaccine protects against swine, human and bird flu
Annual flu shots could become a thing of the past under a new vaccine strategy. A new study describes a vaccine that protects against H1N1 swine flu and can also protect against influenza in humans and birds.
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Targeted nanoparticles show promise for more effective antifungal treatments
Researchers have developed a new nanotechnology-based approach that could improve treatment of fungal infections, particularly those caused by the increasingly drug-resistant Candida species.
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COVID-19 caused by the Omicron variant in lung transplant recipients: a single center case series
A new study investigates the risk factors for developing severe disease in lung transplant patients as a result of the Omicron variant of Covid-19.
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New film series ‘The Deadly Five’ highlights global animal infectious diseases
The EU-funded WiLiMan-ID project is excited to announce the launch of a brand-new short film series, The Deadly Five. This series is aimed at raising awareness of five critical animal infectious diseases, classified as high priority.
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Scientists uncover secrets of cryo-EM structures of Nipah virus polymerase complex
A new investigation into the cryo-EM structures of Nipah virus polymerase complex reveals highly varied interactions between L and P proteins among paramyxoviruses.
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Discovery opens up for new ways to treat chlamydia
Researchers have discovered a type of molecule that can kill chlamydia bacteria but spare bacteria that are important for health.
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Global review of bird flu in cats points to risk of another pandemic
Bird flu (H5N1) is rapidly evolving into the possibility of a human pandemic, say researchers who have been documenting research on bird flu in cats and calling for urgent surveillance of cats to help avoid human-to-human transmission.