Latest News in WAAW – Page 21
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AI reveals critical gaps in global Antimicrobial Resistance research
Researchers developed global maps showcasing regional, methodological, and sectoral AMR research activities, confirming a lack of interdisciplinary collaboration, particularly in low-income countries, where the burden of increasing AMR is most acute.
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Researchers may have come up with second chance for antibiotic agent
A new study focuses on the protein peptide deformylase (PDF), which is involved in protein maturation processes in bacterial cells. While the original drug candidate had to be discarded, modification of the molecule could offer a second chance.
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Study provides new insights into phage therapy design
Results from a new study are providing new insights into the therapeutic potential of bacteriophage (phage) therapy for treating diseases like cystic fibrosis (CF).
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Study paves the way for an active agent against hepatitis E
Tests in cell culture with human liver cells showed that the compound K11777 prevents infection with hepatitis E viruses.
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Biophysicist F. William Studier awarded Merkin prize in biomedical technology
F. William Studier, a senior biophysicist emeritus at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory, has won the 2024 Richard N. Merkin Prize in Biomedical Technology for his development in the 1980s of an efficient, scalable method of producing RNA and proteins in the laboratory. Source: ...
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Your Pseudomonas aeruginosa biofilm may vary - depending on where it turns up
The bacterium Pseudomonas aeruginosa adapts its biofilm form depending on the infectious site where it is found, potentially affecting antibiotic sensitivity, according to new research being presented at the Letters in Applied Microbiology ECS Research Symposium today.
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Herpes cure with gene editing makes progress in laboratory studies
Researchers have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an infected individual.
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Plant virus treatment shows promise in fighting metastatic cancers in mice
An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study.
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Scientists uncover mechanism that could weaken virulence of Pseudomonas aeruginosa
Researchers have found a mechanism that makes it possible to weaken the virulence of opportunistic bacterial pathogen Pseudomonas aeruginosa - based on this knowledge, a new approach for antibiotics can be developed.
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A new acquired defense strategy different from CRISPR activates anti-mycobacteriophage immunity
A new study suggests endogenous insertion sequences (ISs) in mycobacteria can activate the defensive gene islands, thereby helping bacteria quickly acquire a broad-spectrum anti-phage ability.
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Commonly used antibiotic brings more complications, death in the sickest patients
Treatment with the commonly used antibiotic piperacillin/tazobactam was associated with a 5 percent increase in 90-day mortality, more days on a ventilator, and more time with organ failure for patients with sepsis, a new study finds.
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Ancient remedy is reworked to create medicinal cocktail targeting drug-resistant bacteria
A mediaeval remedy used to cure a “lump in the eye” - interpreted as a sign of bacterial infection - more than 1,000 years ago has been reworked into a pharmaceutical product with potent antibiofilm activity, delegates will hear at the Letters in Applied Microbiology ECS Research Symposium.
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Experts ID highly drug-resistant infections in patients who traveled to Mexico for stem cell treatments
Experts in mycobacterial diseases are investigating a potential outbreak of a highly drug-resistant mycobacterium after U.S. patients who traveled to Mexico for stem cell injections became sick.
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Antibiotic resistance genes found deep in sediment of mangroves
Antibiotic resistance genes have been found deep in sediment within mangrove areas in Mexico, a new study has found.
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Scientists probe spermidine production to combat emerging drug resistance in Salmonella
Scientists have pinpointed how Salmonella Typhimurium uses a key molecule called spermidine to shield itself from the onslaught of the host’s defence machinery - and an existing FDA-approved drug can reduce spermidine production.
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Astragalus polysaccharide enhances voriconazole metabolism under inflammatory conditions through the gut microbiota
Astragalus polysaccharide alleviates the reduction of VRC metabolism induced by LPS by inhibiting lipid accumulation and inflammatory cytokine levels in the serum and liver and improving the metabolic function of the liver, a new study shows.
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Decoding the complex genetic network of antimicrobial resistance in Campylobacter jejuni
A study focused on tetracycline resistance genes tetO and tetM - using phylogenetic tree analysis, it provided valuable insights into the genetic landscape and variants associated with C. jejuni.
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AMI welcomes new 5-year UK plan to combat antimicrobial resistance
Applied Microbiology International has welcomed the UK government’s new national action plan on antimicrobial resistance to protect people and animals from the risk of drug-resistant infections.
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Scientists warn of overuse of antibiotics in newborns with suspected sepsis
Newborns in Sweden are given antibiotics for suspected sepsis to an unjustified extent, reveals a study of more than one million newborns. Despite a significant reduction in sepsis rate in the group, the use of antibiotics has not decreased.
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Scientists reveal search for faster way to diagnose MRSA and its relatives
New research being presented at the Letters in Applied Microbiology ECS Symposium reveals the drive to come up with a better way of diagnosing staph infections that would be more cost-effective and less time-consuming.