All Metabolomics articles
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NewsA new light on the microbiome and its metabolites
Two studies shed new light on how plant-based diets support the gut microbiome. One study reveals that plant fibers and proteins reprogram microbial metabolism to boost production of a healthful species of metabolites, while suppressing that of their harmful counterparts.
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NewsHuman activities compromise coral health and resilience
Researchers discovered that 25 contaminants from agricultural, industrial, and pharmaceutical sources accumulated in the soft tissues of coral around Maui, Hawai‘i.
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NewsReview unmasks hidden role of gut microbes in colorectal cancer
A new review systematically dissects how the gut microbiota and host cells talk to each other across four molecular layers – genome, transcriptome, epigenome, and metabolome – and highlights the computational innovations that make such multi‑omics integration possible.
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NewsMicrobes rewrite the rules of cancer immunotherapy by triggering immunogenic cell death
A new study reveals that microbiota and their metabolites can effectively reprogram immunogenic cell death (ICD), a unique form of cell death that activates the body‘s immune system against tumors, transforming immunologically “cold” therapy-resistant tumors into “hot” responsive ones.
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NewsTwo types of biochar help alfalfa survive salty soils
A new study shows that carefully designed biochar can guide plant metabolism and reshape beneficial microbial communities around the roots to help reduce stress from saline-alkali soil.
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NewsNew fluorescent nanosensor enables first-of-its-kind detection of key gut health biomarker
Researchers have developed a novel fluorescent nanosensor capable of rapidly detecting indole-3-propionic acid (IPA), an emerging biomarker linked to gut health and disease. The sensor produces a rapid optical readout within minutes, offering a significantly faster and more accessible alternative to conventional analytical techniques.
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NewsScientists clarify the interplay between host and gut microbiota in selenium metabolism
In a recent study, researchers used rats to investigate how gut microbiota and the host jointly manage selenium metabolism. They found that gut microbiota actively transform selenium into various metabolites that influence selenium utilization, detoxification, and excretion, and that the host’s selenium intake affects bacterial diversity.
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NewsResearchers link human molecular, microbial diversity with geography, ethnicity
Researchers at the Stanford School of Medicine have found that ethnicity and geography may influence human molecular makeup — from metabolism and immunity to gut microbiota and biological aging. The findings, which published in Cell on May 14, illuminate the complex interplay between genetics and the environment, ...
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NewsNew research reveals mechanisms behind coffee’s positive effects on the gut-brain axis
First of its kind research shows the potential role of coffee as a further intervention to promote positive gut health and its effects on the gut-brain axis. Coffee was found to positively affect perceived mood and stress levels in individuals taking part in this study.
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NewsHow gut bacteria and acute stress are linked
Researchers have demonstrated for the first time that, in healthy adults, the diversity of gut bacteria and their capacity to produce certain metabolites are associated with the acute stress response - particularly stress reactivity.
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NewsDecoding the chemical messengers: Gut microbes talk to the whole body through metabolites
A comprehensive review systematically maps how bacterial metabolites shape immune responses and diseases across organs.
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NewsHeart disease risk tied to certain molecules made by gut microbes
In a study involving data from thousands of people, the risk of a new coronary heart disease diagnosis was statistically associated with bloodstream levels of nine specific molecules that are produced by gut microbes.
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NewsFrom gut to lung: A microbial signal that strengthens early immune defense
Researchers report that a gut microbiota–derived metabolite can directly shape immune responses in bacterial pneumonia. Using a Klebsiella pneumoniae infection model, the team demonstrated that butyric acid restores the function of CX3CR1-positive natural killer cells.
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NewsHow periodontitis-linked bacteria accelerate osteoporosis-like bone loss through the gut
Researchers reveal that salivary bacteria from gum disease alter gut metabolism, driving osteoclast activity and systemic bone loss. They analyzed salivary microbiota from individuals with advanced periodontitis and compared them with samples from periodontally healthy donors.
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NewsInvasive death cap mushrooms are changing their chemistry
Scientists have just published new research about the chemistry of death cap mushrooms (Amanita phalloides) - the species is not only spreading rapidly as an invasive fungal species in the United States, but the move across continents has changed the chemistry of the species.
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NewsNew evidence reveals Streptococcus anginosus drives gastric cancer development
A recent study has revealed a novel cancer-promoting mechanism of Streptococcus anginosus. The research shows that methionine metabolites produced by this bacterium can significantly contribute to the development of gastric cancer.
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NewsInside the gut: What our poo could tell us about our diet, gut microbes and health
Researchers have found that molecules in stool samples can accurately reflect what people eat and how their gut microbiome responds, offering a potential new tool to study nutrition and its impact on health.
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NewsMetabolites produced in the intestine play a central role in controlling obesity and diabetes
A study has identified a group of metabolites that travel from the intestine to the liver and then to the heart, where they are pumped throughout the body. These metabolites play an important role in controlling metabolic pathways in the liver and insulin sensitivity.
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NewsCircadian rhythms as a modulator of gut microbiota-tumor microenvironment crosstalk
A new review examines how circadian disruption modifies the diversity and metabolic functions of gut microbiota, resulting in alterations of microbial metabolites, including short-chain fatty acids and secondary bile acids.
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NewsScientists reveal molecular cause behind “stuck” beer fermentation
Premature yeast flocculation (PYF) is a persistent issue in beer brewing, where yeast settles too early during fermentation. New research identifies multiple differential metabolites and confirmed galangin as a key factor that promotes early yeast aggregation.