All Metabolomics articles
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Bacterial protein therapy shows promise as first-ever antidote for carbon monoxide poisoning
Researchers have engineered a new molecule that appears promising as an effective antidote for carbon monoxide poisoning with fewer side effects than other molecules currently being tested.
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Study finds fungus metabolites may help ghost shrimp survive
Researchers have found that chemical byproducts produced by the amphibian-killing fungus Batrachochytrium dendrobatidis—commonly known as Bd—may actually help ghost shrimp survive.
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Study unearths rich rhizodeposits data for better bioenergy crops
Scientists conducted a meticulous analysis of the compounds released by plant roots into their surrounding environment. The analysis yielded an abundance of data that can guide research aiming to improve the way we grow energy and food crops.
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Gut microbes: How many molecules influence our body?
Researchers have precisely quantified how many molecules are produced by gut bacteria and arrive in the body every day, enabling them to calculate how many gut bacteria are used up and regenerated each day.
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Reviving 80-year-old fungi offers new clues for sustainable agriculture
Researchers who revived 80-year-old fungal pathogens from a museum collection found that these pre-Green Revolution strains differ significantly from modern ones, revealing how decades of pesticide use and intensive farming have reshaped plant pathogens.
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New research uncovers gut microbe-derived metabolites as potential therapy for obesity-related metabolic disorders
New research reveals that certain gut microbial byproducts may hold promise as a novel therapy for obesity-associated metabolic complications by restoring critical hormone-producing cells in the intestine.
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New study reveals how corals teach their offspring to beat the heat
A new study shows that rice coral, an important reef-building species, passes on thermal resistance to their offspring and avoids coral bleaching. Understanding this is important to building healthier coral reefs and protecting their future.
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New immunotherapy strategy targets difficult-to-treat brain tumors with gut microbiota
Researchers have demonstrated a new therapeutic strategy that can enhance the efficacy of immunotherapy for brain tumors by utilizing gut microbes and their metabolites. This also opens up possibilities for developing microbiome-based immunotherapy supplements in the future.
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Gut bacteria may hold key to unlocking better cancer treatment
Scientists have discovered a range of microbial ‘biomarkers’ that could help to improve detection and treatment of gastrointestinal diseases (GIDs) such as gastric cancer (GC), colorectal cancer (CRC), and inflammatory bowel disease (IBD).
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Tuberculous meningitis: study shows that metabolism drives mortality
A new study suggests that dysregulated β-oxidation may be an important and potentially modifiable contributor to mortality in tuberculous meningitis.
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Effects of electroacupuncture combined with Chinese herbal medicine on gut microbiota and metabolomics in amyotrophic lateral sclerosis
Studies have highlighted a link between amyotrophic lateral sclerosis (ALS) and gut microbiota. A prospective study aimed to evaluate the effects of electroacupuncture combined with Chinese herbal medicine on gut microbiota and metabolomics in ALS patients.
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Researchers uncover blood metabolites that may influence early childhood development
Researchers have identified small molecules in the blood that may impact early childhood development, showing how dietary exposures, early life experiences, and gut health can influence a child’s growth and cognitive milestones.
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We know what you ate: Detailed protein maps assess intestinal health
A new method has been designed to map the near-exact molecular details of the human and bacterial protein regulations within the host-gut microbiome interactions. These proteins could be used for medical and dietary intervention to maintain intestinal health.
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Precision medicine and inflammatory disease: Power of metabolic modelling to generate personalized probiotics
A research study has recently highlighted the application of large-scale computational modelling of metabolomics in the human gut microbiome to design personalised probiotics for treating gut inflammatory diseases.
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Bacterial small noncoding RNA promotes gut colonization by regulating sialic acid metabolism
A novel 3′ UTR-derived small noncoding RNA was discovered to regulate metabolism of N-acetylneuraminic acid in Salmonella enterica pathogenesis.
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Study uncovers new pathway controlling levels of body fat and cholesterol
Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study.
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Mapping the gut microbiome to create personal nutrition plans
Researchers are developing methods of mapping the microbiome to help create personalized nutrition plans for individuals. They designed metabolomic analyses that are accessible and reusable for dietary research targets such as corn, wheat and citrus.
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Researchers find that intestinal infections change bile composition
Intestinal infections can change the composition of liver bile, leading to changes in immune function and gut bacteria, potentially helping fight off harmful bacteria.
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Study reveals how our gut cells detect harmful invaders
Researchers hve found that the GPR31 path in ‘gut surveillance’ cells detects bacterial metabolites and triggers immune responses, opening new possibilities for drug development, vaccines, and probiotics to fight infections.
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Persistent proteins may influence metabolomics results
Scientists have identified more than 1,000 previously undetected proteins in common metabolite samples, which persist despite extraction methods designed to weed them out.