All Metabolomics articles – Page 2
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NewsGut microbiota: implications in pathogenesis and potential therapeutic target in primary biliary cholangitis
A new review synthesizes current evidence on gut microbiota dysbiosis in PBC, elucidates its pathogenic mechanisms, and explores its potential as both a diagnostic biomarker and a novel therapeutic target.
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NewsThe ‘MDME Axis’: A new view on how microbial metabolites epigenetically shape host health
A review introduces the ’MDME Axis’, a new framework explaining how metabolites from the gut microbiome epigenetically reprogram our genes, influencing host health and disease.
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NewsNew study links gut microbes to common heart disease - suggesting ‘Jekyll and Hyde’ action
Researchers studying gut microbes recently identified 15 bacterial species associated with coronary artery disease. The analysis reveals multiple pathways linked to disease severity, including increased inflammation and metabolic imbalance.
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NewsNew insights on gut microbes that prevent formation of cancer-causing compounds
Gut microbes metabolize dietary nitrates and nitrites and prevent the formation of cancer-causing compounds called nitrosamines. New research sheds light on these processes and pinpoints which types of bacteria are most important.
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NewsMissing nutrient in breast milk may explain health challenges in children of women with HIV
A new study reveals that breast milk from women living with HIV contains significantly lower levels of tryptophan, an essential amino acid likely important for infant immune function, growth, and brain development.
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NewsFertilizer boosts soil’s ability to lock away carbon
The 180-year experiment at Rothamsted — the world’s longest-running agricultural trial — has revealed that long-term application of nitrogen and phosphorus fertilisers can significantly increase the amount of carbon stored in farmland soils, helping to mitigate climate change.
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NewsA triad of metabolites, targeted microbial delivery, and AI-assisted profiling for precision medicine-food intervention
A new perspective delineates a novel paradigm for precision medicine-food intervention, built upon three interconnected directions: (1) targeting key microbial metabolites, (2) advancing targeted delivery technologies for beneficial microbes, and (3) implementing AI-assisted personalized microbiome functional profiling.
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NewsMagnetic fields improve Monascus pigments and inhibit citrinin yield via interfering with the iron metabolism
A research team has reported magnetic fields intensities that could improve the yield of Monascus purpureus fermented products while inhibiting citrinin production without adversely affecting M. purpureus growth.
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NewsBacterial protein therapy shows promise as first-ever antidote for carbon monoxide poisoning
Researchers have engineered a new molecule that appears promising as an effective antidote for carbon monoxide poisoning with fewer side effects than other molecules currently being tested.
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NewsStudy finds fungus metabolites may help ghost shrimp survive
Researchers have found that chemical byproducts produced by the amphibian-killing fungus Batrachochytrium dendrobatidis—commonly known as Bd—may actually help ghost shrimp survive.
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NewsStudy unearths rich rhizodeposits data for better bioenergy crops
Scientists conducted a meticulous analysis of the compounds released by plant roots into their surrounding environment. The analysis yielded an abundance of data that can guide research aiming to improve the way we grow energy and food crops.
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NewsGut microbes: How many molecules influence our body?
Researchers have precisely quantified how many molecules are produced by gut bacteria and arrive in the body every day, enabling them to calculate how many gut bacteria are used up and regenerated each day.
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NewsReviving 80-year-old fungi offers new clues for sustainable agriculture
Researchers who revived 80-year-old fungal pathogens from a museum collection found that these pre-Green Revolution strains differ significantly from modern ones, revealing how decades of pesticide use and intensive farming have reshaped plant pathogens.
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NewsNew research uncovers gut microbe-derived metabolites as potential therapy for obesity-related metabolic disorders
New research reveals that certain gut microbial byproducts may hold promise as a novel therapy for obesity-associated metabolic complications by restoring critical hormone-producing cells in the intestine.
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NewsNew study reveals how corals teach their offspring to beat the heat
A new study shows that rice coral, an important reef-building species, passes on thermal resistance to their offspring and avoids coral bleaching. Understanding this is important to building healthier coral reefs and protecting their future.
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NewsNew immunotherapy strategy targets difficult-to-treat brain tumors with gut microbiota
Researchers have demonstrated a new therapeutic strategy that can enhance the efficacy of immunotherapy for brain tumors by utilizing gut microbes and their metabolites. This also opens up possibilities for developing microbiome-based immunotherapy supplements in the future.
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NewsGut bacteria may hold key to unlocking better cancer treatment
Scientists have discovered a range of microbial ‘biomarkers’ that could help to improve detection and treatment of gastrointestinal diseases (GIDs) such as gastric cancer (GC), colorectal cancer (CRC), and inflammatory bowel disease (IBD).
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NewsTuberculous meningitis: study shows that metabolism drives mortality
A new study suggests that dysregulated β-oxidation may be an important and potentially modifiable contributor to mortality in tuberculous meningitis.
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NewsEffects of electroacupuncture combined with Chinese herbal medicine on gut microbiota and metabolomics in amyotrophic lateral sclerosis
Studies have highlighted a link between amyotrophic lateral sclerosis (ALS) and gut microbiota. A prospective study aimed to evaluate the effects of electroacupuncture combined with Chinese herbal medicine on gut microbiota and metabolomics in ALS patients.
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NewsResearchers uncover blood metabolites that may influence early childhood development
Researchers have identified small molecules in the blood that may impact early childhood development, showing how dietary exposures, early life experiences, and gut health can influence a child’s growth and cognitive milestones.
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