All Microbial Genetics articles – Page 4
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NewsBacteria encode hidden genes outside their genome - so do we?
A new study shows that bacteria can create free-floating and ephemeral genes, raising the possibility that similar genes exist outside of our own genome.
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NewsNovel nanosensing technique offers quality control of viral vectors in gene therapy
Researchers report a novel nanosensing technique to measure viral vector characteristics, measuring the ionic current that flows through a nanopore opening when a voltage differential is applied to a solution containing adeno-associated virus.
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NewsWhen it comes to DNA replication, humans and baker’s yeast are more alike than different
Humans and baker’s yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies.
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FeaturesMicrobiology’s role in sustainable gastronomy
Designated on 21 December 2016 by the UN General Assembly, Sustainable Gastronomy Day is about the celebration of the food that sustains our lives regardless of culture and geology.
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NewsMystery CRISPR unlocked: A new ally against antibiotic resistance?
CRISPR-Cas systems are bacterial adaptive immune systems that target and cut the nucleic acids (DNA/RNA) of invading genetic parasites like bacteriophages (phages); viruses that infect - and eventually kill - bacterial cells. They consist of two main components; the CRISPR array, which stores immune memory of past ...
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NewsBiophysicist F. William Studier awarded Merkin prize in biomedical technology
F. William Studier, a senior biophysicist emeritus at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory, has won the 2024 Richard N. Merkin Prize in Biomedical Technology for his development in the 1980s of an efficient, scalable method of producing RNA and proteins in the laboratory. Source: ...
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NewsHerpes cure with gene editing makes progress in laboratory studies
Researchers have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an infected individual.
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NewsA new acquired defense strategy different from CRISPR activates anti-mycobacteriophage immunity
A new study suggests endogenous insertion sequences (ISs) in mycobacteria can activate the defensive gene islands, thereby helping bacteria quickly acquire a broad-spectrum anti-phage ability.
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NewsResearchers develop an efficient host-vector system for a model archaeon by solving CRISPR-based host-plasmid conflict
The replicase gene of pRN1, an archaeal cryotic plasmid, carries a DNA segment to be targeted by the host I‐A CRISPR system, and the CRISPR-based host-plasmid conflict is responsible for instability of pRN1‐derived vectors in the archaeon Saccharolobus islandicus REY15A.
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NewsDecoding the complex genetic network of antimicrobial resistance in Campylobacter jejuni
A study focused on tetracycline resistance genes tetO and tetM - using phylogenetic tree analysis, it provided valuable insights into the genetic landscape and variants associated with C. jejuni.
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NewsScientists ID transcripts involved in antibiotic resistance mechanism of two critical superbugs
A new study uncovers a drug resistance gene’s divergent evolution, which could open new vistas for MDR prognosis and can be informative in antimicrobial therapeutics research.
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NewsResearchers track the virus behind India’s lumpy skin cattle crisis
A study provides critical insights into the evolution and origins of the virus strains fueling a devastating outbreak of lumpy skin disease, which has severely affected India’s agricultural sector, leading to staggering economic losses.
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NewsHIV in cell culture can be completely eliminated using CRISPR-Cas gene editing technology
New research demonstrates transport of new-gene editing technology to ‘cut out’ HIV DNA from infected cells; preliminary findings are “very encouraging”, but much work is needed to transform the technology into a cure for HIV.
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NewsVirus that infected the first animals now essential for development of the human embryo
All animals have evolved thanks to the fact that certain viruses infected primitive organisms hundreds of millions of years ago. Researchers now describe the role played by these viruses in a process that is absolutely vital for our development.
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NewsNew tool reveals gene behavior in bacteria
Researchers showed that the way in which genes are turned on and off as bacteria grow provide clues to their regulation.
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NewsMaking probiotics more widely applicable through ‘CRISPR’ engineering
Scientists review the recent progress and challenges in the production and use of genetically modified probiotics.
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NewsGenetic fingerprint suggests cutaneous leishmaniasis may be gaining foothold in US
Analysis reveals DNA evidence of a US-acquired strain of cutaneous leishmaniasis - the prospect of a growing threat comes amidst concerns that domestic sand flies could acquire a deadly form of the disease via dog imports.
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NewsNICER than CRISPR: new gene editor reduces unintended mutations
Researchers led by Osaka University develop a new gene modification technique known as NICER that significantly reduces off-target mutations in DNA.
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NewsResearchers discover genes behind AMR in deadly superbug infections
Australian researchers have uncovered new genetic insights into Staphylococcus aureus, revealing what makes the bacterium so dangerous when it enters the blood.
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CareersNew research IDs 28 genetic regions linked to susceptibility and severity of COVID-19
A study identifies 51 significant genome-wide loci associated with both COVID-19 severity and SARS-CoV-2 susceptibility, providing valuable information about the disease.