All Microbial Genetics articles – Page 2
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NewsHow soil microbes adapt to life in lakes
Researchers have analyzed the genome of bacteria living in Lake Zurich to conclude that microbes employ two different strategies to colonize new habitats. Some acquire new traits – but others reduce the size of their genome and lose some functions in order to successfully move to a new home.
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NewsGene sheds light on how parasites exit host cells
Researchers have elucidated the parasite exit process - known as egress - after identifying an essential gene, MIC11. To clearly explain egress, the behaviors of Toxoplasma gondii were assessed.
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NewsNew bite-sized CRISPR molecule may open doors for therapeutic genome editing
The safest, most accurate gene-editing tools don’t fit inside viral delivery mechanisms that could target them to specific cell types or tissues inside the human body. Researchers have developed a smaller pair of “molecular scissors” for gene editing that could make site-specific delivery within the body possible.
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NewsUnexpected potential bacterial symbiosis found in fungus that causes angular leaf spot
Scientists have uncovered an unexpected microbial relationship that could help explain differences in the severity of a major disease affecting common beans. The discovery sheds light on how the pathogen evolves and may point to new strategies.
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NewsA single gene, a dramatic change: CRISPR unlocks white strawberries
Researchers used CRISPR/Cas9 to selectively edit a single dominant gene copy controlling fruit color in the commercial octoploid strawberry cultivar ‘Florida Brilliance’. By targeting the MYB10-1B gene, they successfully converted red strawberries into stable white-fruited plants.
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NewsMicroplastics in soil may reshape microbial genes and threaten ecosystem stability
A new review highlights how microscopic plastic particles accumulating in soils can alter microbial genes that control essential ecosystem functions, potentially affecting food production, climate processes, and environmental health.
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NewsA yeast enzyme helps human cells overcome mitochondrial defects
An international team has experimentally uncoupled nucleotide synthesis from mitochondrial activity using ScURA, a yeast-derived genetic tool now available to the research community that will enable new explorations of cellular metabolism.
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NewsScientists’ chemical breakthrough sheds light on origins of life
Researchers have discovered a tiny RNA molecule that could explain how life on Earth began. The findings reveal the team has identified a remarkably small ribonucleic acid (RNA) molecule, named QT45, that can copy itself and its complementary strand.
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NewsGenetic system makes worker cells more resilient producers of nanostructures
Researchers report the development of a new genetic regulatory system to improve cell viability during the production of gas vesicles.
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NewsNew tool shows how to enter and change pneumocystis fungi
Researchers have reported success in genetically modifying the fungal pathogen Pneumocystis murina. Their approach uses extracellular vesicles from mouse lungs to deliver gene-modifying molecules inside the fungal cells. The modified fungus expressed the introduced genomic modifications.
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NewsHow genes influence the microbes in our mouths
A new study has found human genetic factors that influence the oral microbiome and may increase risk of cavities and tooth loss in some people. Analysis of the now largest collection of oral microbiome profiles reveals interactions between human and bacterial DNA.
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News3′UTR-derived small RNA couples acid resistance to metabolic reprogramming in Salmonella within macrophages
Salmonella expresses the arginine decarboxylase AdiA, which confers acid resistance by catalyzing an H+-consuming reaction. Researchers have discovered that the 3′-untranslated region (UTR) of adiA mRNA is processed by RNase E into a regulatory small RNA, AdiZ.
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NewsAncient DNA pushes back record of treponemal disease-causing bacteria by 3,000 years
Scientists have recovered a genome of Treponema pallidum from 5,500-year-old human remains in Sabana de Bogotá, Colombia. The research expands knowledge about the history of this infectious disease and its occurrence in human populations.
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NewsEndogenous retroviruses promote early human zygotic development
New findings offer insight into why some embryos fail to develop past zygotic genome activation (ZGA), pointing to an unexpected root of human infertility.
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NewsPlant discovery could lead to new ways of producing medicines
Scientists studying a plant called Flueggea suffruticosa, which produces a particularly powerful alkaloid known as securinine, investigated how this chemical is made - and discovered that the process is driven by a gene that looks more like it comes from bacteria than from a plant.
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NewsChanges in genetic structure of yeast lead to disease-causing genomic instabilities
Researchers studying a yeast model have discovered that the loss of heterochromatin can kickstart genetic changes, potentially resulting in the development of diseases like cancer.
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NewsCRISPR discovery could lead to single diagnostic test for COVID, flu, RSV
Researchers report newly discovered details about the Cas12a3 immune system that precisely targets transfer RNA in invading pathogens, without destroying host cells.
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NewsStudy identifies a molecular switch that controls transitions between single-celled and multicellular forms
How did multicellular life evolve from single cells? Researchers have identified genes in marine yeast that may help answer this fundamental question.
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NewsCandida auris: genetic process revealed which could be treatment target for deadly fungal disease
Scientists have discovered a genetic process which could unlock new ways to treat a mysterious and deadly fungal infection which has shut down multiple hospital intensive care units.
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NewsResearch reveals how ancient viral DNA shapes early embryonic development
New research focuses on a viral transposable element called MERVL. This element becomes highly active for a short window of time when a mouse embryo reaches the 2-cell stage – the point at which a fertilised egg has divided into two cells and switches on its own genome for the first time.