All Microbial Genetics articles
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News
Biophysicist F. William Studier awarded Merkin prize in biomedical technology
F. William Studier, a senior biophysicist emeritus at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory, has won the 2024 Richard N. Merkin Prize in Biomedical Technology for his development in the 1980s of an efficient, scalable method of producing RNA and proteins in the laboratory. Source: ...
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Herpes cure with gene editing makes progress in laboratory studies
Researchers have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an infected individual.
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A new acquired defense strategy different from CRISPR activates anti-mycobacteriophage immunity
A new study suggests endogenous insertion sequences (ISs) in mycobacteria can activate the defensive gene islands, thereby helping bacteria quickly acquire a broad-spectrum anti-phage ability.
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Researchers develop an efficient host-vector system for a model archaeon by solving CRISPR-based host-plasmid conflict
The replicase gene of pRN1, an archaeal cryotic plasmid, carries a DNA segment to be targeted by the host I‐A CRISPR system, and the CRISPR-based host-plasmid conflict is responsible for instability of pRN1‐derived vectors in the archaeon Saccharolobus islandicus REY15A.
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Decoding the complex genetic network of antimicrobial resistance in Campylobacter jejuni
A study focused on tetracycline resistance genes tetO and tetM - using phylogenetic tree analysis, it provided valuable insights into the genetic landscape and variants associated with C. jejuni.
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Scientists ID transcripts involved in antibiotic resistance mechanism of two critical superbugs
A new study uncovers a drug resistance gene’s divergent evolution, which could open new vistas for MDR prognosis and can be informative in antimicrobial therapeutics research.
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Researchers track the virus behind India’s lumpy skin cattle crisis
A study provides critical insights into the evolution and origins of the virus strains fueling a devastating outbreak of lumpy skin disease, which has severely affected India’s agricultural sector, leading to staggering economic losses.
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HIV in cell culture can be completely eliminated using CRISPR-Cas gene editing technology
New research demonstrates transport of new-gene editing technology to ‘cut out’ HIV DNA from infected cells; preliminary findings are “very encouraging”, but much work is needed to transform the technology into a cure for HIV.
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Virus that infected the first animals now essential for development of the human embryo
All animals have evolved thanks to the fact that certain viruses infected primitive organisms hundreds of millions of years ago. Researchers now describe the role played by these viruses in a process that is absolutely vital for our development.
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New tool reveals gene behavior in bacteria
Researchers showed that the way in which genes are turned on and off as bacteria grow provide clues to their regulation.
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Making probiotics more widely applicable through ‘CRISPR’ engineering
Scientists review the recent progress and challenges in the production and use of genetically modified probiotics.
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Genetic fingerprint suggests cutaneous leishmaniasis may be gaining foothold in US
Analysis reveals DNA evidence of a US-acquired strain of cutaneous leishmaniasis - the prospect of a growing threat comes amidst concerns that domestic sand flies could acquire a deadly form of the disease via dog imports.
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NICER than CRISPR: new gene editor reduces unintended mutations
Researchers led by Osaka University develop a new gene modification technique known as NICER that significantly reduces off-target mutations in DNA.
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Researchers discover genes behind AMR in deadly superbug infections
Australian researchers have uncovered new genetic insights into Staphylococcus aureus, revealing what makes the bacterium so dangerous when it enters the blood.
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Careers
New research IDs 28 genetic regions linked to susceptibility and severity of COVID-19
A study identifies 51 significant genome-wide loci associated with both COVID-19 severity and SARS-CoV-2 susceptibility, providing valuable information about the disease.
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Genetic tools probe minuscule bacteria that live on surface of larger bacteria
Scientists have elucidated genes needed for the unusual lifestyle of miniscule bacteria that live on the surface of larger bacteria.
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One gene cluster switches fungus from beneficial to harmful
Scientists studying a pathogenic strain of a root fungus have found that activation of a single fungal secondary metabolism gene cluster determined the negative impact of the fungus on the host plant.
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First defence against devastating ToCSV tomato virus explored
How tomato plants defend themselves against a devastating ‘young’ Southern African virus has now been investigated at a molecular genetics level for the first time.
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Team find promising bacterial suicide gene against citrus Huanglongbing and canker
Researchers have found that an endolysin encoded by the CaLas prophage has dual resistance to Huanglongbing and citrus canker.
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Researchers find chink in the armour of tuberculosis pathogen
Discovery of drug resistance network could clear way for developing a drug to prevent pathogen from resisting and tolerating tuberculosis treatment.