The replicase gene of pRN1, an archaeal cryotic plasmid, carries a DNA segment to be targeted by the host I‐A CRISPR system, and the CRISPR-based host-plasmid conflict is responsible for instability of pRN1‐derived vectors in the archaeon Saccharolobus islandicus REY15A.
Included as a benefit
Members of Applied Microbiology International have unlimited access to The Microbiologist as a benefit of membership. Just sign in with your usual membership credentials.
Find out more about how to join.
FREE
Want to read more before deciding on a subscription? It only takes a minute to sign up for a free account and you’ll get to enjoy more free content each month.
3.75 per month / £35 annually
Get unlimited access to The Microbiologist.