All Microbial Genetics articles
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NewsNabsys announces first publication showcasing CRISPR/Cas9 mediated approach to expand the capabilities of electronic genome mapping
This study is the first to demonstrate the potential of combining Electronic Genome Mapping (EGM) with CRISPR/Cas9 to both characterize CRISPR/Cas9 activity and enhance the capabilities of genome mapping.
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NewsNew study uncovers how the malaria parasite boosts its transmission potential under stress conditions
Researchers reveal the molecular mechanism by which Plasmodium falciparum responds to stress by increasing the production of the sexual forms required for transmission.
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NewsDeleting yeast DNA to save lives
People with weakened immune systems and some other conditions can experience an overgrowth of Candida yeasts, leading to a type of infection known as candidiasis. It might be possible to save these patients by using CRISPR to delete the very genes that let infectious Candida resist treatment - but which genes are responsible?
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NewsKey regulator helps seafood-associated bacterium balance iron and oxidative stress
Bacteria need iron, but bioavailable iron is often scarce, and too much can fuel chemical reactions that damage cells. Many Gram-negative bacteria balance iron through ferric uptake regulator (Fur), a metal-responsive protein that controls iron-related genes. Fur’s role in V. parahaemolyticus, however, had not been clearly defined.
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NewsDogs and cats carry antibiotic-resistant bacteria also found in people, study finds
Pets may carry strains of Klebsiella pneumoniae — a potentially serious bacterium that can cause infections that are also found in humans. The study is the first to map the global genetic makeup of K.pneumoniae carried by domestic dogs and cats, and to compare it on a large scale with the same bacteria in people.
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NewsThese bacteria can change their diet to survive inside the body
The team have found that Staphylococcus aureus can adjust its diet depending on what sources remain available. The bacterium can adjust its inner workings in response to any one of a number of different sulfur-containing compounds — like cysteine, glutathione or thiosulfate.
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NewsA pan-sRNome analysis identifies novel regulatory small RNAs involved in Pseudomonas aeruginosa virulence
A characterization of nine newly discovered sRNAs reveals their regulatory networks in quorum sensing, biofilm formation, and interbacterial competition in Pseudomonas aeruginosa.
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NewsResearch explores why strep throat can linger, even after treatment with antibiotics
Streptococcal sore throat can linger even after treatment, turning otherwise healthy children into carriers. Using whole genome sequencing, researchers hope to discover why.
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NewsA fourth T6SS in clinical Pseudomonas aeruginosa deploys the pore-forming effector TseMt
The hospital-associated pathogen Pseudomonas aeruginosa has type VI secretion systems (T6SSs). Most reference strains encode three T6SSs, but comparative genomics has identified an additional H4-T6SS in a subset of clinical isolates.
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NewsHidden DNA in medieval gospels reveal history of deadly livestock virus
New research shows that some of Europe’s most well-known historic manuscripts, including the York Gospels, have proven to be biological time capsules for uncovering the 3,500-year history of the sheeppox virus (SPPV).
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NewsFirst results published from major algal gene sequencing project
A new study reveals that different species of microscopic algae can behave in strikingly different ways because of their genetics.
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NewsPediatric investigation review emphasizes the evolving landscape of pediatric enterovirus infections
A review article highlights how rapid viral evolution of enteroviruses combined with shifting dominant strains and antigenic variation present a major obstacle to EV prevention and control in children.
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NewsNew artificial intelligence method to support real-time management of infectious diseases
Scientists used a deep learning artificial intelligence method known as neural posterior estimation (NPE) to study how pathogens evolve, the first time this method has been used with genetic data in a phylodynamic application.
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NewsSharpening an essential tool for biotechnology
Scientists develop a database of validated guide RNAs to improve engineering of microbes for manufacturing applications.
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NewsResearchers zap microbe DNA in the name of food safety
A new study investigates eBeam (electron beam) technology, demonstrating its ability to control food pathogens without jeopardising meat quality.
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NewsMouth and gut microbes could help detect gastrointestinal cancers
Researchers report that by analyzing the make-up of oral microbes it may be possible to detect signals associated with stomach and colorectal cancer. These findings could lead to the development of new, less-invasive screening tests for gastrointestinal cancers.
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NewsMapping plant-fungus symbiosis, cell by cell.
Scientists have produced the first high-resolution, cell-by-cell map of how tomato roots respond to colonization by arbuscular mycorrhizal fungi, a partnership which help plants absorb nutrients from the soil.
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NewsResearchers identify rapidly spreading genetic variants that make parasites resistant to malaria treatment
New genetics study helps explain declining malaria drug susceptibility and highlights the urgent need to track mutations and improve current therapies.
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NewsStable RNA elements open new possibilities for mRNA therapeutics
New research has discovered compact viral RNA elements that can make mRNA more stable, and could provide a simple way to develop longer-lasting and more efficient mRNA technologies for vaccines and other RNA-based therapeutics.
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NewsDolphin blow may reveal the health status of these marine mammals
An international team of researchers has developed a new methodology to identify potential pathogens in dolphin blow.