All Microbial Genetics articles
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NewsCaught in the act: A gene jumps into the void
Self-splicing introns are a special group of jumping genes. It is more difficult for a gene to jump into another cell or another species. Until now, it had been assumed that, for this to happen, the jumping genes travelled as ‘hitchhiker’ in the genomes of plasmids or viruses, but researchers have made a surprising observation.
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NewsPlant viruses open new routes for gene editing
A new study has developed potyvirus-derived vectors for delivering CRISPR RNA (crRNA) guides in Lachnospiraceae bacterium ND2006 Cas12a (LbCas12a)-expressing plants, expanding virus-induced gene editing from tobacco rattle virus (TRV) to tobacco etch virus (TEV), turnip mosaic virus (TuMV), and lettuce mosaic virus (LMV).
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NewsResearch forecasts global antimicrobial resistance threats for the next two decades
New research has analysed antimicrobial resistance (AMR) on a global scale to predict how resistance patterns could evolve by the year 2050, identifying around 210 resistance traits that could pose the greatest future risk.
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NewsHow exercise fights implant infections: Muscle hormone “musclin” unveiled as a key defender
A new study reveals how the exercise-induced myokine musclin reprograms macrophage metabolism to clear dead cells and treat periprosthetic joint infections.
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NewsBacteria organise themselves into diverse, coordinated communities in order to travel across large distances
A new study examined the migration of microbial communities over long distances, and found bacteria migrate not as solitary swimmers, but in diverse, coordinated communities that also contain viruses and “hitchhiking” microbes that cannot swim on their own.
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NewsDolichol biosynthesis conserved across eukaryotes, not limited just to humans
Researchers say a newly proposed three-step “detour” pathway for making dolichol may be more universal than scientists realized. Experiments in yeast suggest eukaryotes may rely on overlapping biochemical pathways, including the evolutionarily conserved “detour” and evidence of a possible “backup route,” to produce a molecule essential to life.
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NewsRedesigning an elusive bacterial enzyme into an efficient green catalyst
Scientists engineer the CYP107J1 enzyme from Bacillus subtilis into a more practical tool for selective oxidation chemistry.
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NewsStarvation triggers reversible epigenetic changes in fish pathogen
What happens to a bacterial pathogen when food runs out—for several months? A new study reveals that Flavobacterium columnare, a deadly aquatic pathogen responsible for columnaris disease in fish, does not change its DNA sequence during prolonged starvation. Instead, it remodels its epigenetic landscape.
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NewsYeast study uncovers how cells identify and silence unwanted jumping genes
Yeast cells sense abnormal RNA patterns produced by invading transposons and respond by activating pathways to silence them, a study shows. This process extends to any invasive DNA, provided it produces enough RNA disturbance for cells to detect.
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NewsStudy reveals “bet-hedging” strategy that helps gut bacteria survive and recover
Researchers have discovered that many gut bacteria use a flexible survival strategy to withstand disruptions such as antibiotics and diet changes. Microbes can switch between functional states, rather than relying solely on genetic mutations, to try to survive shifting conditions.
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NewsAs day turns to night, blue-green algae undergo a molecular rewiring
Traditionally, biotechnology researchers have modified genes when engineering microbes. But researchers are using predictive phenomics to uncover additional layers of biological control, tracking how environmental changes reshape molecular activity inside a cell and how those shifts translate to function.
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NewsHidden small RNA determines if cholera bacterium can infect humans
Scientists have uncovered what gives Vibrio cholerae, the bacterium that causes cholera, the ability to colonize the human gut. They found that a small RNA embedded within another gene controls where cholera thrives, a discovery that could improve prediction and prevention strategies.
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NewsAndelyn Biosciences launches LVV Curator® Platform
Andelyn Biosciences has announced the launch of its LVV Curator® Platform, a standardized lentiviral vector (LVV) manufacturing solution built on the same proven modular approach that supports clinical and commercial adeno-associated virus (AAV) programs.
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NewsAnti-CRISPR stops the protein assembly line in bacteria
Bacteria fend off invading viruses with molecular scissors that slice up viral DNA, but viruses can fight back with a molecular trick that stops the scissors from ever being made. A viral “anti-CRISPR” protein sits on the ribosome and jams it as a CRISPR protein named Cas12 begins to form.
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NewsResearchers flip the CRISPR script to develop world’s first DNA-guided gene editing tool for precise infectious disease diagnosis
A research team has successfully developed the world’s first DNA-guided CRISPR-Cas system capable of programmable RNA targeting and cleavage. This breakthrough overturns the conventional CRISPR paradigm, which uses RNA as a guide to target DNA.
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NewsMalaria’s mRNA: Messages that mess with the immune system
A new study uncovers the malaria parasite’s RNA strategies – mechanisms that could inspire unexpected applications for RNA-based tools in multiple areas of medicine.
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NewsGene-sharing myth challenged as bacteria shown to police DNA exchange
A new study reveals that bacteria can actively limit the spread of antibiotic resistance genes, using a newly characterized mechanism that blocks DNA transfer between cells. It focuses on how bacteria exchange genetic material through tiny intercellular bridges known as nanotubes.
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NewsTiny switch controls rare rotary machine in bacteria - and can even reverse direction of spin
Researchers have discovered a tiny molecular switch that can control and reverse the direction of a rare rotary machine linked to motility, surface colonization and protein secretion in bacteria.
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NewsNew insights into how bacteria manage DNA
New analytical methods have enabled researchers to uncover how the sequence, physical shape and flexibility of bacterial DNA guide the activity of an enzyme called DNA gyrase, which previously got all the credit for managing DNA.
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NewsAntibiotic resistance genes found in newborns within hours of birth, study shows
Antibiotic resistance genes can be present in newborns within the first hours of life. The study analysed meconium samples from 105 infants admitted to a neonatal intensive care unit (NICU) within the first 72 hours of life between July 2024 and July 2025.