All Microbial Genomics articles
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NewsSecond gene implicated in malaria chloroquine resistance evolution
How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene. Now, scientists have shown a second key gene is also involved in malaria’s resistance to the drug chloroquine.
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Fitness landscape explains Covid variant origins
Researchers have uncovered the mechanisms behind the emergence of new and dangerous coronavirus variants, such as Alpha, Delta, Omicron, and others.
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HIV targeted with novel dual gene-editing approach
Gene-editing therapy aimed at two targets – HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells – can effectively eliminate HIV infection, new research shows.
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CRISPR pioneers invent cutting-edge genome edit tool
The team that first discovered the CRISPR loci has now developed a new genome engineering tool that tackles some of the limitations of the most popular CRISPR-based tools.
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Machine learning helps to ID microbe preferences
Researchers have figured out a way to predict bacteria’s environmental pH preferences from a quick look at their genomes, using machine learning.
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New method may harness radiation-resistant bacterium
Researchers find a novel way to expand applications of the hardy bacterium Deinococcus radiodurans, using gene deletion techniques.
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Genomic surveillance may track evolution of emerging wheat disease fungus
Genomic surveillance may be an effective disease management tool against the wheat blast pandemic, with the ability to trace lineages of emerging crop diseases, and to identify genetic traits for breeding disease-resistant lines, a study suggests.
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Microbes that “eat together” may benefit from a shared immunological memory
A new study examines viruses that infect microbes in the deep sea and finds evidence that viruses interact with a far more diverse set of hosts than was previously thought.
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Scientists reveal how getting physical can tackle a key hurdle in synthetic biology
A team of scientists may have solved one of the biggest hurdles standing in the way of synthetic biology - the difficulty of transferring the resulting large DNA molecules into bacterial host cells.
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Methanogen genomes reveal how life thrives in extreme conditions
A comparison of the genomes of methane-producing microorganisms reveals that temperature adaptation might not be genomically encoded, but rather enforced through protein regulation and finer scale adaptations in amino acids.
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mNGS outperforms microbiological tests to diagnose bloodstream infections
Next-generation sequencing (mNGS) leverages genetic testing advantage to save more lives and is found to be twice as effective at identifying infection cases.
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Long Reads
A relationship with benefits: microfungi’s important role in plant health
Explore the work being done at Royal Botanic Gardens, Kew on the fungi associated with soil, seeds and plants and the future of fungal research.
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Ubiquitin protein may be Achilles heel of the flu virus
Researchers have found a trove of potential active ingredients that could help to provide treatment for the influenza virus in the future.
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RIPE researchers add plant protein mechanism into bacteria
A team from the Australian National University (ANU) has modified the protein folding properties of bacteria by adding multiple components from the chloroplast of plants.
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New bacterial product found to inhibit flu virus replication
Researchers have identified a derivative of a bacterial natural product that inhibits the body’s own methyltransferase MTr1, thereby limiting the replication of influenza viruses.
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Novel strain of Shigella in gut of bottom-dwelling fish beats off competition with help of T2SS
A novel strain of Shigella isolated from the gut of a bottom-dwelling fish exposed to high loads of heavy metals and antibiotics has been found to have the first Type 2 secretion system fully documented in the bacterium.
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Researchers scour more than 600 genome sequences in quest for origins of Black Death
Researchers seeking to better understand the origins and movement of bubonic plague have completed a painstaking granular examination of hundreds of modern and ancient genome sequences, the largest analysis of its kind.
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Madagascar mouse lemur retroviruses surprisingly similar to ones found in polar bears or sheep
Researchers studying the mouse lemur genome have identified two endogenous retroviruses (ERVs) that are closely related to viruses found in other, very different mammals such as polar bears or domestic sheep.
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General Biomics and The Jackson Laboratory announce intellectual property licensing agreement
General Biomics, Inc. and The Jackson Laboratory (JAX) have announced an expansive and exclusive intellectual property licensing agreement across six areas of human health.
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Scientists synthesize precursors of powerful anti-cancer drug in yeast cells
Researchers have identified a novel method for the biological synthesis of catharanthine and vindoline - the two pharmacologic precursors of anti-cancer drug vinblastine - using yeast cells.
