All Microbial Genomics articles – Page 5
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News
Scientists reveal how getting physical can tackle a key hurdle in synthetic biology
A team of scientists may have solved one of the biggest hurdles standing in the way of synthetic biology - the difficulty of transferring the resulting large DNA molecules into bacterial host cells.
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Methanogen genomes reveal how life thrives in extreme conditions
A comparison of the genomes of methane-producing microorganisms reveals that temperature adaptation might not be genomically encoded, but rather enforced through protein regulation and finer scale adaptations in amino acids.
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mNGS outperforms microbiological tests to diagnose bloodstream infections
Next-generation sequencing (mNGS) leverages genetic testing advantage to save more lives and is found to be twice as effective at identifying infection cases.
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Long Reads
A relationship with benefits: microfungi’s important role in plant health
Explore the work being done at Royal Botanic Gardens, Kew on the fungi associated with soil, seeds and plants and the future of fungal research.
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Ubiquitin protein may be Achilles heel of the flu virus
Researchers have found a trove of potential active ingredients that could help to provide treatment for the influenza virus in the future.
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RIPE researchers add plant protein mechanism into bacteria
A team from the Australian National University (ANU) has modified the protein folding properties of bacteria by adding multiple components from the chloroplast of plants.
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New bacterial product found to inhibit flu virus replication
Researchers have identified a derivative of a bacterial natural product that inhibits the body’s own methyltransferase MTr1, thereby limiting the replication of influenza viruses.
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Novel strain of Shigella in gut of bottom-dwelling fish beats off competition with help of T2SS
A novel strain of Shigella isolated from the gut of a bottom-dwelling fish exposed to high loads of heavy metals and antibiotics has been found to have the first Type 2 secretion system fully documented in the bacterium.
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Researchers scour more than 600 genome sequences in quest for origins of Black Death
Researchers seeking to better understand the origins and movement of bubonic plague have completed a painstaking granular examination of hundreds of modern and ancient genome sequences, the largest analysis of its kind.
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Madagascar mouse lemur retroviruses surprisingly similar to ones found in polar bears or sheep
Researchers studying the mouse lemur genome have identified two endogenous retroviruses (ERVs) that are closely related to viruses found in other, very different mammals such as polar bears or domestic sheep.
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General Biomics and The Jackson Laboratory announce intellectual property licensing agreement
General Biomics, Inc. and The Jackson Laboratory (JAX) have announced an expansive and exclusive intellectual property licensing agreement across six areas of human health.
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Scientists synthesize precursors of powerful anti-cancer drug in yeast cells
Researchers have identified a novel method for the biological synthesis of catharanthine and vindoline - the two pharmacologic precursors of anti-cancer drug vinblastine - using yeast cells.
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Researchers modify hydrogen-producing enzyme to protect it from oxygen destruction
Researchers have genetically modified a hydrogen-producing enzyme so that it is protected from oxygen, countering a key barrier to producing molecular hydrogen with enzymes from bacteria and algae.
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Scientists discover a new way of sharing genetic information in a common ocean microbe
<i>Prochlorococcus</i>, the world’s most abundant photosynthetic organism, reveals a gene-transfer mechanism that may be key to its abundance and diversity.
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High-efficiency gene-editing tool coaxes fungi into yielding their secrets
Using an approach that simultaneously modifies multiple sites in fungal genomes, Rice University chemical and biomolecular engineer Xue Sherry Gao and collaborators coax fungi into revealing their best-kept secrets, ramping up the pace of new drug discovery.
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CRISPR self-destruct protein may yield new tests for many viruses
A recently discovered protein has been found to act as a kind of multipurpose self-destruct system for bacteria, capable of degrading single-stranded RNA, single-stranded DNA and double-stranded DNA and holding potential for the development of at-home diagnostic tests for a wide range of infectious diseases.
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New mapping tool delivers first accurate tuberculosis genome
Researchers have developed a novel genome assembly tool that could spur the development of new treatments for tuberculosis and other bacterial infections.
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Lasso peptide points the way to new antibiotics for untreatable infections
Princeton Engineering researchers have isolated a compound that kills bacteria that can cause incurable infections.
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International team tracks the global spread of antimicrobial resistance
An international research team has provided valuable new information about what drives the global spread of genes responsible for antimicrobial resistance (AMR) in bacteria.
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Discovery of world’s oldest DNA breaks record by one million years
Microscopic fragments of environmental DNA dating back two million years has been found in Ice Age sediment in northern Greenland, opening a game-changing new chapter in the history of evolution.