All Microbial Genomics articles – Page 6
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NewsCRISPR-like system in eukaryotes can edit the human genome
The first RNA-guided DNA-cutting enzyme found in eukaryotes, Fanzor could one day be harnessed to edit DNA more precisely than CRISPR/Cas systems.
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NewsMapping evolution of E. coli virulence factor offers refined drug target
Researchers have presented evidence that targeting the K1 capsule can be used as the basis of treatment, paving the way to prevent serious E. coli infections.
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NewsSecond gene implicated in malaria chloroquine resistance evolution
How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene. Now, scientists have shown a second key gene is also involved in malaria’s resistance to the drug chloroquine.
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NewsFitness landscape explains Covid variant origins
Researchers have uncovered the mechanisms behind the emergence of new and dangerous coronavirus variants, such as Alpha, Delta, Omicron, and others.
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NewsHIV targeted with novel dual gene-editing approach
Gene-editing therapy aimed at two targets – HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells – can effectively eliminate HIV infection, new research shows.
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NewsCRISPR pioneers invent cutting-edge genome edit tool
The team that first discovered the CRISPR loci has now developed a new genome engineering tool that tackles some of the limitations of the most popular CRISPR-based tools.
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NewsMachine learning helps to ID microbe preferences
Researchers have figured out a way to predict bacteria’s environmental pH preferences from a quick look at their genomes, using machine learning.
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NewsNew method may harness radiation-resistant bacterium
Researchers find a novel way to expand applications of the hardy bacterium Deinococcus radiodurans, using gene deletion techniques.
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NewsGenomic surveillance may track evolution of emerging wheat disease fungus
Genomic surveillance may be an effective disease management tool against the wheat blast pandemic, with the ability to trace lineages of emerging crop diseases, and to identify genetic traits for breeding disease-resistant lines, a study suggests.
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NewsMicrobes that “eat together” may benefit from a shared immunological memory
A new study examines viruses that infect microbes in the deep sea and finds evidence that viruses interact with a far more diverse set of hosts than was previously thought.
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NewsScientists reveal how getting physical can tackle a key hurdle in synthetic biology
A team of scientists may have solved one of the biggest hurdles standing in the way of synthetic biology - the difficulty of transferring the resulting large DNA molecules into bacterial host cells.
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NewsMethanogen genomes reveal how life thrives in extreme conditions
A comparison of the genomes of methane-producing microorganisms reveals that temperature adaptation might not be genomically encoded, but rather enforced through protein regulation and finer scale adaptations in amino acids.
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NewsmNGS outperforms microbiological tests to diagnose bloodstream infections
Next-generation sequencing (mNGS) leverages genetic testing advantage to save more lives and is found to be twice as effective at identifying infection cases.
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Long ReadsA relationship with benefits: microfungi’s important role in plant health
Explore the work being done at Royal Botanic Gardens, Kew on the fungi associated with soil, seeds and plants and the future of fungal research.
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NewsUbiquitin protein may be Achilles heel of the flu virus
Researchers have found a trove of potential active ingredients that could help to provide treatment for the influenza virus in the future.
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NewsRIPE researchers add plant protein mechanism into bacteria
A team from the Australian National University (ANU) has modified the protein folding properties of bacteria by adding multiple components from the chloroplast of plants.
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NewsNew bacterial product found to inhibit flu virus replication
Researchers have identified a derivative of a bacterial natural product that inhibits the body’s own methyltransferase MTr1, thereby limiting the replication of influenza viruses.
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NewsNovel strain of Shigella in gut of bottom-dwelling fish beats off competition with help of T2SS
A novel strain of Shigella isolated from the gut of a bottom-dwelling fish exposed to high loads of heavy metals and antibiotics has been found to have the first Type 2 secretion system fully documented in the bacterium.
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NewsResearchers scour more than 600 genome sequences in quest for origins of Black Death
Researchers seeking to better understand the origins and movement of bubonic plague have completed a painstaking granular examination of hundreds of modern and ancient genome sequences, the largest analysis of its kind.
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NewsMadagascar mouse lemur retroviruses surprisingly similar to ones found in polar bears or sheep
Researchers studying the mouse lemur genome have identified two endogenous retroviruses (ERVs) that are closely related to viruses found in other, very different mammals such as polar bears or domestic sheep.