The National Institutes of Health recently awarded the University of Kansas $5.8 million for Phase 3 of KU’s Chemical Biology of Infectious Disease center, an NIH Center of Biomedical Research Excellence (COBRE) that was established in 2016. The center recruits, mentors and supports investigators across KU, KU Medical Center, Kansas State, Wichita State and other regional partners as they address urgent challenges in infectious disease and antibiotic resistance using chemical-biology approaches. A Phase 3 award is intended to help a research center along a sustainable path beyond COBRE support at the federal level.
Until now, no one has observed a human gene that is both mobile and required for bodily functions. Scientists have found a human genetic element in a poxvirus and discovered it was both an important gene for brain function and a jumping gene capable of moving and inserting itself in genomes.
A polyphenol-rich extract from Cistus salviifolius demonstrated fungicidal activity against several dermatophytes and decreased fungal infection in a laboratory model of human epidermis.
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A new tool to mutate bacteriophages – viruses that infect bacteria – provides a big leap forward in both our understanding of how they function, and our ability to harness their full potential. The new method allows for genome-wide mutagenesis of bacteriophages using CRISPR-Cas technology.
Before the parasite Toxoplasma gondii can invade a cell, it has to know it has reached the right place. New research from the Whitehead Institute reveals that the parasite doesn’t simply recognize a ready-made doorway into the cell. Instead, it helps create the conditions for its own entry.
Researchers have created an inexpensive, quick and accurate handheld device that can detect seven mosquito-borne illnesses. Their design could help clinicians in low-resource or remote settings — from clinics in rural Haiti to farm animal veterinarians — diagnose patients without the need for a power supply, bulky equipment or extensive training.
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