All USA & Canada articles
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Scientists hack microbes to identify environmental sources of methane
A new paper reveals how the activity of one of the main microbial enzymes involved in producing methane affects the isotope composition used as a fingerprint of various environmental sources.
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Maternal antibodies in breast milk regulate early immune responses in mouse gut
In mice, maternal antibodies ingested in breast milk in the first week after birth help to regulate immune responses in the newborn gut, according to a new study.
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Researchers use generative AI to design compounds that can kill drug-resistant bacteria
With help from artificial intelligence, researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA).
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1 in 3 US adults unaware of connection between HPV and cancers
The human papillomavirus (HPV) can cause six types of cancer, yet new analysis shows that most people are unaware of the connection between HPV and all of these cancers.
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A microbial DNA signature differentiates two types of cancer in the liver
Researchers have identified a microbial DNA signature in blood plasma that reliably differentiates primary liver cancer from colorectal cancer that has spread to the liver (metastatic colorectal cancer).
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Study finds tiny microbes shape brain development
New research finds that microbes play an important role in shaping early brain development, specifically in a key brain region that controls stress, social behavior, and vital body functions.
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One universal antiviral to rule them all?
Taking inspiration from a rare mutation that makes people impervious to viral diseases, a researcher is developing a therapy that could bestow this superpower on the rest of us. The mutation causes a deficiency in an immune regulator called ISG15.
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Mount Sinai creates first manual for treating infection-associated chronic illness for clinicians
Mount Sinai has launched the country’s first clinical manual for treating infection-associated chronic illnesses (IACIs). This comprehensive guide, prepared by the Cohen Center for Recovery From Complex Chronic Illnesses, part of the Department of Rehabilitation and Human Performance, will help clinicians better diagnose and care for patients with conditions such ...
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‘Controlled evolution’ dramatically boosts pDNA production for biomedical manufacturing
Researchers have controlled the evolution of E. coli bacteria in the lab in order to dramatically increase the amount of plasmid DNA (pDNA) these modified bacteria produce. pDNA is an essential – and expensive – ingredient in many gene therapies.
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Flu fighters: researchers take a closer look at immune response to influenza
Researchers sought to identify which immune cells in pigs have receptors that are most reactive to influenza. They accomplished this by customizing a technology called single-cell RNA sequencing for pigs to learn more about how a body’s cells operate at a highly detailed level.
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Two-dose therapy for S. aureus bloodstream infections on par with standard treatment
A clinical trial has found that the outcome of treating complicated Staphylococcus aureus bloodstream infections with two intravenous (IV) doses of the antibiotic dalbavancin seven days apart is just as good as daily IV doses of conventional antibiotics over four to six weeks.
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Bacterial protein therapy shows promise as first-ever antidote for carbon monoxide poisoning
Researchers have engineered a new molecule that appears promising as an effective antidote for carbon monoxide poisoning with fewer side effects than other molecules currently being tested.
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Scientists find a microbial molecule that restores liver and gut health
Researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure. The treatment may offer a new, non-toxic way to prevent and treat non-alcoholic fatty liver disease (NAFLD).
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Study looks for markers that predict risk of severe chlamydia infection
A new study has identified markers that may predict whether a chlamydia infection is likely to ascend into the uterus and endometrium. The work could lead to new diagnostics that can predict a woman’s risk of severe infection.
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As school returns, so do infections & asthma emergencies. Where kids live can make it worse
A new study highlights how neighborhood conditions shape the seasonal surge of virus-triggered asthma emergencies. It found that children in under-resourced communities face sharply higher rates of asthma flare-ups tied to viral infections during the first weeks of school.
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Portable spectroscopy enables detection of vaginal microbes
Surface-enhanced Raman spectroscopy can rapidly and noninvasively detect specific bacterial species in vaginal fluid, enabling early identification of microbiome imbalances.
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Fast, accurate, low-cost diagnostics - and no lab required
Researchers have developed a breakthrough diagnostic tool that could transform how quickly and reliably we detect illnesses like COVID-19, Ebola, AIDS or Lyme disease. The test uses just a single drop of blood, costs a couple of dollars and delivers results in only 15 minutes.
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Seventy-year-old Parkinson’s drug shows promise against tuberculosis
A medication developed in the 1950s to treat Parkinson’s disease may offer a powerful new tool in the fight against tuberculosis. The study found that benztropine can dramatically reduce levels of TB-causing bacteria by boosting the body’s natural immune response.
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Common food thickeners – long thought to pass right through us – are actually digested
It turns out cellulose-based thickening agents can be digested. Researchers have shown that our gut bacteria can feed on these large molecules – thought to not be possible – thanks to enzymes that normally help us break down dietary fibre.
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Study: Long COVID remains a substantial financial and medical burden
Individuals with long COVID-19 experienced worse financial and employment outcomes – lasting up to three years after their initial infection. Notably, vaccination against COVID-19 was associated with strikingly improved work and financial outcomes.