All USA & Canada articles – Page 6
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NewsTrial tests virus-immunotherapy combination for neuroendocrine tumors
A phase I clinical trial is testing whether a tumor-targeting virus can help immunotherapy work more effectively against aggressive neuroendocrine tumors that often resist treatment. The ongoing study has completed its first three dose levels with no severe treatment-related side effects reported to date.
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NewsMicrobiome insights may help predict immunotherapy benefit in kidney cancer
City of Hope researchers report that gut microbiome composition may influence how patients respond to immunotherapy combinations in metastatic renal cell carcinoma, pointing to a potential biomarker that could help guide treatment selection in the future. The microbiome is a rising focus at City of Hope, highlighted ...
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NewsModern medicine makes gut microbial diversity plummet
Even minimal exposure to modern medicine can rapidly change the human microbiome. Researchers reveal that the gut microbes of remote Amazonian Indigenous communities began shifting toward patterns more commonly seen in urban, industrialized populations after only a few medical visits.
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NewsScientists make groundbreaking discovery – and find a possible new ally – in the opioid crisis
Scientists analyzed used hypodermic needles from a needle exchange program to better understand what narcotics actually were in the needles and determine if any non-viral pathogens were present.
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NewsChemists use sea sponge bacteria to create new molecules for drug discovery
Chemists have synthesized new molecules derived from bacteria found in a Pacific Ocean sea sponge. They are the first to successfully synthesize two new marine natural products: tetradehydrohalicyclamine B and epi-tetradehydrohalicyclamine B.
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NewsHPV self-collection boosts cervical cancer screening rates
The first major U.S. rollout of HPV self-collection shows benefits for patients and providers, including fewer pelvic exams and better follow-up for HPV-positive results.
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NewsHospital wastewater reveals drug-resistant fungus strains months before patients show symptoms
A study reveals that sampling raw wastewater closer to the source — sewer lines that directly serve hospitals, retirement homes, and long-term care facilities — allows scientists to detect drug-resistant strains of Candida auris as many as five months before patients begin showing symptoms.
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NewsNew clinical study shows pasteurized Akkermansia muciniphila MucT supports weight loss maintenance
A clinical trial demonstrates that supplementation with pasteurized Akkermansia muciniphila MucT® significantly improved weight loss maintenance in adults with overweight or obesity following an initial weight loss intervention.
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NewsScientists harness T cells to help the body fight entire viral families
Scientists have discovered that combining key vaccine ingredients could give the body the tools it needs to fight the entire family of arenaviruses with a single vaccine, protecting against life-threatening infections from Lassa virus, Junin virus, and other arenaviruses with pandemic potential.
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NewsPatent targets viruses with a breakthrough from linseed oil
A common vegetable oil may hold the key to fighting some of the world’s most dangerous viruses. Scientists have patented a linseed oil polyol-derived compound shown to inhibit viral infections including HIV and SARS-CoV-2 as well as bacterial infections causing strep and staph.
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NewsTicks are ‘spreading like wildfire’ - and more of them are carrying Lyme
Not only are tick numbers growing in the US, but today’s ticks are more likely to carry Lyme disease bacteria and other dangerous pathogens. Researchers have noticed a greater diversity of ticks, suggesting a complex pattern of movement and perhaps the introduction or reintroduction of animals, including birds.
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NewsHealthcare utilization disruptions continue in post-COVID China
Although China’s stringent public health policy, Dynamic Zero-Covid, was lifted in late 2022, researchers have discovered substantial, long-term declines in outpatient clinic visits and hospitalizations compared to expected levels from 2020 to 2024 in China.
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NewsLargest-ever Canadian clinical trial tests ‘poop pills’ to improve immunotherapy for lung cancer
For nearly half of people diagnosed with lung cancer, immunotherapy can slow the disease but not stop it. A clinical trial will pair immunotherapy with fecal microbiota transplantation (FMT) with the goal of safely increasing treatment effectiveness. If successful, it could provide new treatment options for people with lung cancer.
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Careers The First Microbiome Symposium of Puerto Rico and the Caribbean – new success for the COBRE Center for Microbiome Sciences
The inaugural Microbiome Symposium of Puerto Rico and the Caribbean marked a major milestone for microbiome science in the region and reinforced Puerto Rico’s growing leadership in interdisciplinary biomedical research, says chair Filipa Godoy-Vitorino of the University of Puerto Rico.
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NewsResearchers discover the secret behind gray mold’s unstoppable spread
For years, scientists have unsuccessfully tried to breed crops that could resist Botrytis cinerea. New research suggests decades of crop breeding strategies may have overlooked a crucial piece of the puzzle: the pathogen itself. The problem may lie in a fundamental misunderstanding of how plants and the pathogen interact.
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NewsProtected areas that help wildlife often do little for the soil fungi that plants depend on
Scientists built the most comprehensive models ever of the ranges of 2,858 important fungal species and compared them with the world’s protected landscapes. More than half of these critical underground organisms are less protected than if conservation areas had been drawn at random.
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NewsRevealing the invisible: a new baseline for Salish sea diatoms answers a global call
Diatoms are powerful in driving roughly 20% of global photosynthesis and forming the very base of marine food webs. Scientists have published a new checklist of 924 diatom taxa alongside a curated dataset of 11,469 records, providing a long-needed foundation for environmental monitoring across the Salish Sea bioregion.
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NewsNew research offers practical biosecurity tools to limit poultry disease spread
New research could help producers better protect poultry flocks from disease outbreaks while reducing costs. By identifying where contamination occurs and how to interrupt those pathways, the research helps move biosecurity from theory to action, offering tools that can protect animal health and support a more stable food supply.
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NewsA common disinfectant could affect how well your liver works
Common household cleaners and pharmaceutical products contain benzalkonium chlorides (BACs), a type of disinfectant. A new study shows that exposure to these compounds caused changes in gut microbiome composition in mice, as well as the genes that encode for liver enzymes that metabolize drugs.
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NewsStudy reveals “bet-hedging” strategy that helps gut bacteria survive and recover
Researchers have discovered that many gut bacteria use a flexible survival strategy to withstand disruptions such as antibiotics and diet changes. Microbes can switch between functional states, rather than relying solely on genetic mutations, to try to survive shifting conditions.