All USA & Canada articles – Page 6
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Bat virus evolution suggests wildlife trade sparked COVID-19 virus emergence in humans
The ancestor of the virus that causes COVID-19 left its point of origin in Western China or Northern Laos just several years before the disease first emerged in humans up to 2,700 kilometers away in Central China, suggesting the wildlife trade played a role.
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Breakthrough discovery uses gut bacteria and AI to diagnose a chronic pain syndrome
Scientists have developed AI technology that can detect patterns in gut bacteria to identify complex regional pain syndrome (CRPS) with remarkable accuracy, potentially transforming how CRPS is diagnosed and treated.
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High-density screening technique reveals key genes for biotechnology improvements
Scientists used a gene-silencing tool and molecular guides to probe how photosynthetic bacteria adapt to light and temperature changes, finding even partial suppression of certain genes yielded big benefits in modifying the stress response of wild microbes.
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Long COVID may cause long-term changes in the heart and lungs and may lead to cardiac and pulmonary diseases
Patients suffering from long COVID may exhibit persistent inflammation in the heart and lungs for up to a year following SARS-CoV-2 infection, potentially placing them at elevated risk for future cardiac and pulmonary conditions.
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Biological patterns: Stability through protein reservoirs
Biophysicists have figured out how bacteria form robust patterns despite changing environmental conditions and fluctuating protein concentrations.
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New CDC nPEP Guidelines should become ‘part of general medical practice’
Health experts say the updated CDC HIV Non-Occupational Post Exposure Prophylaxis (nPEP) Guidelines should be part of general medical practice, as incorporating them will reduce new HIV infections and improve public health.
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Electricity-generating bacteria may power future innovations
Scientists have discovered how certain bacteria breathe by generating electricity, using a natural process that pushes electrons into their surroundings instead of breathing on oxygen.
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Clinical trial underway for potential Long COVID treatment
A clinical trial is underway to assess the effectiveness and safety of sipavibart, AstraZeneca’s long-acting monoclonal antibody designed to provide protection against Covid-19, as a potential treatment for Long Covid.
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Urban rats spread deadly bacteria as they migrate, study finds
Urban rats spread deadly bacteria as they migrate within cities that can be the source of a potentially life-threatening disease in humans, according to a six-year study that also discovered a novel technique for testing rat kidneys.
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Scientists introduce new engineered drug candidate for Mycobacterium abscessus to save lives
Scientists have introduced a promising drug candidate engineered to target a deadly and emerging infection. They took a hyper-detailed look into the problem of Mycobacterium abscessus, and chemically re-engineered a widely-used rifamycin antibiotic.
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Ultimate self-sacrifice: Bacteria activate unusual defense to evade viral attack
Scientists discover that the restriction modification system in some bacteria can kill the cell as a last resort if viruses try to thwart it. They trigger their own death using components of the very same systems that the phages were trying to inhibit.
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AI plays detective to help scientists find hidden microbes
A team of researchers has created a novel machine learning tool that’s cracking open one of biology’s trickiest puzzles: finding the rarest microbes on Earth. Ulrb not only identifies rare microorganisms but also works with non-microbial data.
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Topical gel relieved ear infections in animals after just one dose
Researchers report a topical antibiotic gel that, applied once, cured middle ear infection within 24 hours in chinchillas. a single dose of treatment for middle ear infections could improve patient compliance and potentially reduce pediatric antibiotic usage.
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New molecular label could lead to simpler, faster tuberculosis tests
Chemists have demonstrated that they can label a glycan called ManLAM using an organic molecule that reacts with specific sulfur-containing sugars. These sugars are found in only three bacterial species, including the microbe that causes TB.
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Placebo-testing vaccines is unethical, ‘a waste of time and money,’ expert says
The proposal to require that all new vaccines undergo safety testing in placebo-controlled trials is ethically problematic and will slow testing down for no good reason, warn scientists.
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Antibodies that recognize lipids: A new path for HIV vaccines and autoimmune disease treatments
Scientists have used computer modeling to illustrate how a specific class of antibodies actually use lipids to recognize the HIV virus. The work highlights antibody features that could help people design better vaccines for HIV and autoimmune diseases.
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Scientists uncover the link between ‘good’ gut bacteria and rheumatoid arthritis
After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown how activity of “good” microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.
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$2.7 million NIH grant to fund first comprehensive syphilis test
With a four-year, $2.7 million grant from NIAID, researchers aim to develop a one-step confirmatory laboratory test that can definitively diagnose active syphilis infection within 10 minutes.
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Monoclonal antibody nirsevimab provides strong protection against severe RSV in infants
Nirsevimab, a monoclonal antibody, is highly effective in real-world conditions at preventing severe respiratory syncytial virus (RSV) infections in infants, suggests a meta-analysis.
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A digestive ‘treasure chest’ shows promise for targeted drug treatment in the gut
A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments.