All USA & Canada articles
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NewsUnique bond identified as key to viral infection speed
Viruses are typically described as tiny, perfectly geometric shells that pack genetic material with mathematical precision, but new research reveals a deliberate imbalance in their shape that helps them infect their hosts.
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NewsResearchers discover how Ebola and Marburg disrupt the gastrointestinal tract
A new study sheds light on the mechanisms behind the damage caused by Ebola (EBOV) and Marburg virus (MARV) to the gastrointenstinal tract. TIt found that both viruses are capable of infecting and replicating within human gut epithelial cells and that the viruses interfere with the cells’ ability to regulate fluid secretion, mirroring the severe symptoms observed in patients.
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NewsStudy shows why mRNA-based COVID-19 vaccines can cause myocarditis
Investigators have unearthed the biological process by which mRNA-based vaccines for COVID-19 can cause heart damage in some young men and adolescents — and they’ve shown a possible route to reducing its likelihood.
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NewsIn pneumonia’s tug-of-war, lung microbiome could tip the balance
Scientists have found the lungs’ own microbial community, or microbiome, appears to influence how pneumonia evolves, who responds well to treatment and whether a patient will recover successfully or continue to deteriorate.
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NewsOlder age, chronic kidney disease and cerebrovascular disease linked with increased risk for paralysis and death after West Nile virus infection
Older people with a history of chronic kidney disease or conditions affecting blood flow to the brain such as stroke face about double the risk for developing neuroinvasive disease that can lead to paralysis and death following infection with West Nile virus, new research finds.
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NewsNew 15-minute hepatitis C test paves the way for same-day treatment
Scientists have developed the fastest test yet for diagnosing hepatitis C virus (HCV). The highly accurate diagnostic delivers results to patients in just 15 minutes - crucial for kickstarting patients’ treatment before they leave their appointment.
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NewsOpioid use linked to higher risk of C. difficile infection
New research from the University of Georgia suggests that opioid use could make patients more vulnerable to infections. The meta-analysis examined four studies of almost 120,000 patients. The researchers found that about 31% of patients who were prescribed and taking opioids caught C. diff, compared to 17% of patients who weren’t using them.
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NewsStudy reveals promising gut-targeted therapy for C. difficile infections
Researchers have uncovered how the body’s bile acids bind to block C. diff’s most dangerous toxin. The research has informed the development of a new compound that can protect against C. diff in preclinical models, offering hope for safer, more effective treatments.
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NewsHuman ‘mini-noses’ help understand why RSV infections are more severe in children than in adults
Why does RSV affect babies more severely? To better understand the cellular reasons behind this age-related difference, researchers compared infant and adult human nose organoids, also called mini-noses, regarding their susceptibility and response to infection.
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NewsReceptors in mammary glands make livestock and humans inviting hosts for avian flu
A new study shows that the mammary glands of several other production animals besides cows – including pigs, sheep, goats, beef cattle and alpacas – are biologically suitable to harbor avian influenza, due to high levels of sialic acids.
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NewsInstitutions team up to advance first AI-designed mRNA vaccine against deadly tick-borne disease
Scientists are developing what could become the world’s first mRNA vaccine against severe fever with thrombocytopenia syndrome (SFTS)—a tick-borne viral disease associated with this condition.
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NewsCARB-X to support investigation of Exhalon’s breath-based lower respiratory tract infection testing platform
CARB-X has awarded Exhalon US$1M in seed funding to evaluate whether exhaled breath can be used as a non-invasive sample type to aid in the rapid and accurate diagnosis of lower-respiratory tract infections (LRTIs).
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NewsStudy suggests that chlorine treatment may impact the risk of legionnaires’ disease
Preliminary results of a nationwide study suggest that the disinfectant used to treat water before it is distributed through pipes may impact the incidence of Legionnaire’s disease in certain parts of the country.
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NewsHow did Bronze Age plague spread? Ancient sheep might solve the mystery
Researchers have found the first evidence of a Bronze Age plague infection in a non-human host. The scientists discovered Y. pestis DNA in a 4,000-year-old domesticated sheep from Arkaim, a fortified settlement located in the Southern Ural Mountains of present-day Russia.
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NewsTuberculosis: Scientists develop novel drug candidate for combating resistant pathogens
Researchers have developed a promising new substance for targeting bacteria that cause tuberculosis. The team have produced a compound that inhibits the pathogens’ ability to produce energy and causes them to die.
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NewsOld molecules show promise for fighting resistant strains of COVID-19 virus
SARS‑CoV‑2 continues to mutate, with some newer strains becoming less responsive to current antiviral treatments like Paxlovid. Now, researchers have identified several promising molecules that could lead to new medications capable of combating these resistant variants.
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NewsNew study reveals how natural humic substances reshape soil carbon cycling and boost antibiotic resistance
Researchers have uncovered surprising links between natural humification processes in soil, carbon metabolism, and the spread of antibiotic resistance. Subtle shifts in the composition of humic substances can reshape microbial metabolism and alter the abundance of antibiotic resistance genes.
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NewsHow can nursing homes protect more patients from infections?
New US national guidance calls for full-time infection prevention staff; more training, support and vaccination for all staff; and partnerships with hospitals and public health agencies.
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NewsWhat are the new guidelines for infant hepatitis B vaccination?
Public health expert and infectious disease physician Janet A. Jokela comments after the Advisory Committee on Immunization Practices of the CDC voted to discontinue its decades-long recommendation for universal vaccination against hepatitis B beginning at birth.
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NewsMajor breakthrough against diabetes thanks to a microbial molecule that disarms inflammation
Researchers have uncovered a surprising ally in the fight against insulin resistance and type 2 diabetes: a microbial metabolite called trimethylamine. TMA, produced by gut bacteria from dietary choline can block a key immune pathway and improve blood sugar control.