All USA & Canada articles – Page 4
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Scientists discover how cells use a secret weapon to fight off some pathogens
New research shows that mitochondria detect invading pathogen Toxoplasma gondii and ramp up competition for vitamin B9, depriving it of the nourishment it needs to grow. A researcher noticed that the amount of mitochondrial DNA in a mitochondrion increased during infection.
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Common cold may protect against COVID-19 according to researchers
A new study has found that recent infection with the common cold — often caused by rhinoviruses — may offer temporary protection against infection with SARS-CoV-2, the virus that causes COVID-19.
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Bacteria strains infecting cattle and humans in US are highly similar
Salmonella Dublin, a type of bacteria that primarily infects cattle but some strains also can adapt to infect humans, is increasingly becoming resistant to antibiotics, making it a growing public health threat.
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New African swine fever vaccine candidate shows promise against some virus strains
An international team of scientists has found that a promising African swine fever (ASF) vaccine can protect pigs against some strains of the virus but offers little or no protection against others.
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Kidney fibrosis linked to molecule made by gut bacteria
A molecule made by bacteria in the gut can hitch a ride to the kidneys, where it sets off a chain reaction of inflammation, scarring and fibrosis — a serious complication of diabetes and a leading cause of kidney failure.
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New AI tool reveals how drugs kill tuberculosis
A new study offers a powerful AI-assisted method for uncovering exactly how TB drugs kill the bacteria, opening the door to smarter treatment combinations that could work faster.
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Scientists hack microbes to identify environmental sources of methane
A new paper reveals how the activity of one of the main microbial enzymes involved in producing methane affects the isotope composition used as a fingerprint of various environmental sources.
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Maternal antibodies in breast milk regulate early immune responses in mouse gut
In mice, maternal antibodies ingested in breast milk in the first week after birth help to regulate immune responses in the newborn gut, according to a new study.
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Researchers use generative AI to design compounds that can kill drug-resistant bacteria
With help from artificial intelligence, researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA).
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1 in 3 US adults unaware of connection between HPV and cancers
The human papillomavirus (HPV) can cause six types of cancer, yet new analysis shows that most people are unaware of the connection between HPV and all of these cancers.
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A microbial DNA signature differentiates two types of cancer in the liver
Researchers have identified a microbial DNA signature in blood plasma that reliably differentiates primary liver cancer from colorectal cancer that has spread to the liver (metastatic colorectal cancer).
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Study finds tiny microbes shape brain development
New research finds that microbes play an important role in shaping early brain development, specifically in a key brain region that controls stress, social behavior, and vital body functions.
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One universal antiviral to rule them all?
Taking inspiration from a rare mutation that makes people impervious to viral diseases, a researcher is developing a therapy that could bestow this superpower on the rest of us. The mutation causes a deficiency in an immune regulator called ISG15.
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Mount Sinai creates first manual for treating infection-associated chronic illness for clinicians
Mount Sinai has launched the country’s first clinical manual for treating infection-associated chronic illnesses (IACIs). This comprehensive guide, prepared by the Cohen Center for Recovery From Complex Chronic Illnesses, part of the Department of Rehabilitation and Human Performance, will help clinicians better diagnose and care for patients with conditions such ...
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‘Controlled evolution’ dramatically boosts pDNA production for biomedical manufacturing
Researchers have controlled the evolution of E. coli bacteria in the lab in order to dramatically increase the amount of plasmid DNA (pDNA) these modified bacteria produce. pDNA is an essential – and expensive – ingredient in many gene therapies.
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Flu fighters: researchers take a closer look at immune response to influenza
Researchers sought to identify which immune cells in pigs have receptors that are most reactive to influenza. They accomplished this by customizing a technology called single-cell RNA sequencing for pigs to learn more about how a body’s cells operate at a highly detailed level.
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Two-dose therapy for S. aureus bloodstream infections on par with standard treatment
A clinical trial has found that the outcome of treating complicated Staphylococcus aureus bloodstream infections with two intravenous (IV) doses of the antibiotic dalbavancin seven days apart is just as good as daily IV doses of conventional antibiotics over four to six weeks.
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Bacterial protein therapy shows promise as first-ever antidote for carbon monoxide poisoning
Researchers have engineered a new molecule that appears promising as an effective antidote for carbon monoxide poisoning with fewer side effects than other molecules currently being tested.
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Scientists find a microbial molecule that restores liver and gut health
Researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure. The treatment may offer a new, non-toxic way to prevent and treat non-alcoholic fatty liver disease (NAFLD).
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Study looks for markers that predict risk of severe chlamydia infection
A new study has identified markers that may predict whether a chlamydia infection is likely to ascend into the uterus and endometrium. The work could lead to new diagnostics that can predict a woman’s risk of severe infection.