All USA & Canada articles – Page 8
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NewsUrban rats spread deadly bacteria as they migrate, study finds
Urban rats spread deadly bacteria as they migrate within cities that can be the source of a potentially life-threatening disease in humans, according to a six-year study that also discovered a novel technique for testing rat kidneys.
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NewsScientists introduce new engineered drug candidate for Mycobacterium abscessus to save lives
Scientists have introduced a promising drug candidate engineered to target a deadly and emerging infection. They took a hyper-detailed look into the problem of Mycobacterium abscessus, and chemically re-engineered a widely-used rifamycin antibiotic.
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NewsUltimate self-sacrifice: Bacteria activate unusual defense to evade viral attack
Scientists discover that the restriction modification system in some bacteria can kill the cell as a last resort if viruses try to thwart it. They trigger their own death using components of the very same systems that the phages were trying to inhibit.
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NewsAI plays detective to help scientists find hidden microbes
A team of researchers has created a novel machine learning tool that’s cracking open one of biology’s trickiest puzzles: finding the rarest microbes on Earth. Ulrb not only identifies rare microorganisms but also works with non-microbial data.
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NewsTopical gel relieved ear infections in animals after just one dose
Researchers report a topical antibiotic gel that, applied once, cured middle ear infection within 24 hours in chinchillas. a single dose of treatment for middle ear infections could improve patient compliance and potentially reduce pediatric antibiotic usage.
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NewsNew molecular label could lead to simpler, faster tuberculosis tests
Chemists have demonstrated that they can label a glycan called ManLAM using an organic molecule that reacts with specific sulfur-containing sugars. These sugars are found in only three bacterial species, including the microbe that causes TB.
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NewsPlacebo-testing vaccines is unethical, ‘a waste of time and money,’ expert says
The proposal to require that all new vaccines undergo safety testing in placebo-controlled trials is ethically problematic and will slow testing down for no good reason, warn scientists.
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NewsAntibodies that recognize lipids: A new path for HIV vaccines and autoimmune disease treatments
Scientists have used computer modeling to illustrate how a specific class of antibodies actually use lipids to recognize the HIV virus. The work highlights antibody features that could help people design better vaccines for HIV and autoimmune diseases.
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NewsScientists uncover the link between ‘good’ gut bacteria and rheumatoid arthritis
After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown how activity of “good” microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.
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News$2.7 million NIH grant to fund first comprehensive syphilis test
With a four-year, $2.7 million grant from NIAID, researchers aim to develop a one-step confirmatory laboratory test that can definitively diagnose active syphilis infection within 10 minutes.
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NewsMonoclonal antibody nirsevimab provides strong protection against severe RSV in infants
Nirsevimab, a monoclonal antibody, is highly effective in real-world conditions at preventing severe respiratory syncytial virus (RSV) infections in infants, suggests a meta-analysis.
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NewsA digestive ‘treasure chest’ shows promise for targeted drug treatment in the gut
A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments.
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NewsDesigner microbe shows promise for reducing mercury absorption from seafood
Scientists who inserted DNA-encoding methylmercury detoxification enzymes into the genome of an abundant human gut bacterium found it detoxified methylmercury in the gut of mice and dramatically reduced the amount that reached other tissues.
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NewsStudy of facial bacteria could lead to probiotics that promote healthy skin
Researchers have revealed the dynamics of interactions between two dominant skin bacterial species in more detail than previously possible, shedding light on when and how new bacterial strains emerge on the skin of the face.
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NewsBacterial villain behind Lake Erie’s ‘potent toxin’ unveiled by study
In Lake Erie, cyanobacteria can proliferate out of control, creating algal blooms that produce toxins that can harm wildlife and human health. Researchers have IDed the organism responsible for the toxins: a cyanobacteria called Dolichospermum.
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NewsProtein sources change the gut microbiome – some drastically
A new study shows that protein sources in an animal’s diet can have major effects on both the population and function of the gut microbiome. The two largest effects of dietary protein were on amino acid metabolism and complex sugar degradation.
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NewsBacteria deployed as living test tubes to study human gene mutations
Bioengineers have developed a new simple approach to rapidly check on human gene changes and also screen chemicals as potential drugs by turning everyday bacteria into living test tubes.
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NewsNew AI technique can uncover antiviral compounds using limited data
Artificial intelligence algorithms have been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus 71 (EV71), the pathogen behind most cases of hand, foot and mouth disease.
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NewsNew study reveals emerging cases of babesiosis in Mid-Atlantic region
A newly published study provides critical insights into the emergence of babesiosis in the Mid-Atlantic region, documenting human cases and the presence of Babesia microti in local tick populations.
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NewsPediatric investigation review discusses the challenges, innovations, and future directions in dengue vaccine development
A new review discusses the current status and implications of dengue vaccines like CYD-TDV, TAK-003, and Butantan-DV while exploring the challenges in Dengue vaccine development like ADE, and proposes future directions in this field.