All USA & Canada articles – Page 10
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NewsResearchers develop new vaccine adjuvant that could make it easier to eradicate polio
Researchers have now come up with a way to modify the injectable polio vaccine so that it can also promote a mucosal immune response. This vaccine could help to achieve polio eradication while avoiding the risks of the oral polio vaccine.
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NewsResearchers discover a new antibiotic — and a new way to kill drug-resistant bacteria
Researchers have discovered a new antibiotic that kills some of the world’s most dangerous and drug-resistant bacteria by targeting a previously unknown vulnerability. Manikomycin has shown early effectiveness against priority pathogens including Salmonella, E. coli, and Klebsiella.
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NewsResearcher studying probiotics to fight acid reflux and esophageal cancer
Patients with acid reflux, which occurs when stomach acid pushes up into the esophagus, know the symptoms all too well: heartburn, belching, chest pain and trouble swallowing. Acid reflux also increases the risk of esophageal cancer, but researchers are investigating how a simple probiotic could treat and prevent both conditions.
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NewsNew climate-based tool predicts coral bleaching months in advance
Researchers found that coral bleaching on a Caribbean island occurs when three major climate patterns in the Pacific and Atlantic Oceans align in specific ways that intensify ocean warming. They created a new, early-warning tool called the Bleaching Event Early Predictor (BEEP).
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NewsStudy reveals core values that drive Black and Hispanic parents’ decisions on vaccinating their kids against COVID-19
Persistently low rates of COVID-19 vaccination in Black and Hispanic children suggest that parents in these communities tend to be hesitant about the vaccine for their kids, even when they have received it themselves. A new study sheds light on the factors influencing decisions about vaccination.
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NewsResearchers discover how to turn one germ’s drug resistance into an Achilles’ heel
As Mycobacterium tuberculosis mutates to protect itself from rifampicin, it also creates new weak points that other therapies could exploit. A new study shows that the most common rifampicin-resistance mutation slows bacterial RNA polymerase, creating vulnerabilities that future combination therapies may be able to target.
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NewsGladstone launches Center for PhAIge Therapy to harness AI in the fight against drug-resistant infections
Gladstone Institutes has received funding to establish the Center for PhAIge Therapy, a research center that will develop new phage-based treatments for antibiotic-resistant bacterial infections. The five-year grant makes Gladstone one of three institutions across the country selected to lead this coordinated effort.
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NewsT cells may be key to stopping measles virus—and its deadly relatives
Scientists have discovered how T cells target paramyxoviruses, a viral family that includes measles virus and Nipah virus. Instead of vaccinating against one virus at a time, the researchers found that activating “cross-reactive” T cells may protect against the wider paramyxovirus family.
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NewsPopular GLP-1 drug may slow down biological aging in people with HIV
A new study provides the first randomized, placebo-controlled clinical evidence that semaglutide, a widely used GLP-1 drug, slows down the accumulation of biological aging markers in the DNA of adults with HIV.
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NewsStudy identifies serious infection risks linked to targeted cancer therapies
A major real-world study has found serious blood-related side effects associated with antibody-drug conjugates, an increasingly important class of targeted cancer therapies. Some ADCs were associated with substantial rates of severe neutropenia – dangerously low levels of infection-fighting white blood cells – and related complications.
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NewsPhase 1 clinical trial set to begin on first leishmaniasis vaccine
A phase 1 clinical trial testing the safety of a leishmaniasis vaccine is set to begin in the coming months. The live vaccine, found to be safe in animals, is expected to be tested in humans later this year.
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NewsResearchers evaluate NASA medication storage protocols
Researchers evaluated NASA’s medication handling practices, which currently call for removing medications from their original packaging and storing them in resealable plastic bags. The investigation found that active pharmaceutical ingredients degrade at a higher rate when stored in bags.
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NewsNew study uncovers why the Arctic’s rivers are rusting
Scientists have identified the two biggest reasons that once-pristine rivers across the Arctic are growing cloudy with toxic orange iron particles that smother insects and suffocate fish. As the climate warms, a layer of Arctic soil that had been frozen for millennia has begun to thaw.
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News‘Accidental’ discovery lays foundation for novel flu treatment strategies
Scientists investigating how influenza viruses replicate within cells “accidentally” discovered that different flu viruses use distinct strategies to infiltrate cells in the first place. They also found that it is possible to target specific molecules to prevent the viruses from entering new cells, thereby stopping their replication.
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NewsEngineered gut bacteria therapy emerges as scalable potential alternative to fecal microbiota transplants following clinical trial
Researchers have developed a new manufacturing platform for producing targeted mixtures of beneficial gut bacteria, an approach that could help expand access to microbiome-based therapies for patients with recurrent Clostridioides difficile (C. difficile) infection.
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NewsReal-time brain monitor detects infections earlier
A research team has created a new monitoring system to save lives and significantly reduce health-care costs in brain-injury cases through the early detection of infections in intensive care units. NeuroSense connects to drainage lines to detect biomarkers of infection.
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NewsScientists map the ocean’s invisible workforce
A new study identifies a small set of “metabolic niches” — or functional roles — that help explain how marine microbes grow, compete for resources and recycle carbon around the globe. The microbes are incredibly diverse, but their behavior can be grouped into a manageable number of strategies.
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NewsWhat is the link between HIV and chronic pain?
A mouse study reveals a mechanism linking HIV to chronic pain. Targeting each of the molecular players in this mechanism alleviates pain and may hold treatment promise for HIV-associated pain, though more work is needed.
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NewsOne simple trick makes zebrafish a better model for microbiome research
A new advance in animal husbandry involving a popular aquarium fish should speed the pace of discovery in laboratory studies of host-microbe interactions, researchers report.
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NewsBehind the diagnosis: How laboratory testing guided a complex histoplasmosis case
A diagnosis of histoplasmosis forced a teenager with juvenile arthritis onto an uncertain path, one defined by months of treatment, recovery, and a long-term course of antifungal therapy expected to last up to three years. Histoplasma capsulatum, a dimorphic fungus that causes histoplasmosis, found its way into her lungs.