All Viruses articles
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Cohort data from Denmark show real-world evidence of stable protection against HPV-related cervical cancer
Denmark has been offering free vaccination against human papillomavirus (HPV) to girls since 2008. New data show vaccination has effectively reduced infections with cancerogenic HPV 16/18 types covered by the vaccine, indicating population immunity.
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Scientists ID new drug target for treating cancer and viral infections
An international team of researchers has identified a molecular mechanism that regulates the activity of N-myristoyltransferases, enzymes that ensure the proteins’ function by chemically modifying them during their production.
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Chameleon plant polysccharide targets acute pneumonia with H1N1 and MRSA coinfection
A new study discusses how an anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA coinfection through rectifying Treg/Th17 imbalance in the gut–lung axis and NLRP3 inflammasome activation.
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Global trends and cross-country inequalities of acute hepatitis E in the elderly, 1990–2021
Acute hepatitis E (AHE) in the elderly can lead to severe complications including liver failure and mortality. A new study aimed to assess the trends and health inequalities of AHE among the elderly over the past three decades, and predict its changes by 2030.
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Structure of tick-borne virus revealed at atomic resolution for the first time
One emerging tick-borne virus in North America is the Powassan virus (POWV), which can cause encephalitis, seizures, paralysis and coma. Rates of POWV infections have increased in recent years and currently, there are no treatments available.
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Summer travel ‘will increase the spread of measles,’ expert says
The number of measles cases in the U.S. has reached its highest point in 33 years, and outbreaks are expected to continue, especially amid national and international travel.
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From COVID to cancer, new at-home ‘coffee-ring’ test spots disease with startling accuracy
A new, low-cost biosensing technology could make rapid at-home tests up to 100 times more sensitive to viruses like COVID-19. The diagnostic could expand rapid screening to other life-threatening conditions like prostate cancer and sepsis as well.
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Scientists investigate gut microbiota in elderly patients with acute hepatitis E infection
A new study of the impact of hepatitis E virus infection on the gut microbiota identifies a bacterial species as a potential biomarker for disease outcomes.
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Vanderbilt and Parse Biosciences collaborate on new measles treatment
Vanderbilt University Medical Center and Parse Biosciences, an innovator in single-cell sequencing, are collaborating on a new treatment to help unvaccinated measles victims, as the U.S. measles outbreak has now reached its highest case count in 30 years.
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Cancer-fighting herpes virus shown to be an effective treatment for some advanced melanoma
A genetically engineered herpes simplex virus, when combined with immunotherapy, reduces or eliminates tumors in one-third of clinical trial patients, according to a new study.
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Tiny antibody has big impact on deadly viruses
Researchers have discovered a strategy to neutralise two lethal viruses for which there is currently no approved vaccine or cure. The team identified the first ever nanobody to work against Nipah and Hendra, henipaviruses which have jumped from animals to people.
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Researchers find compound that inhibits cutaneous HPVs
Researchers have identified a promising new compound that inhibits cutaneous HPV. In lab studies, the compound inhibited viral replication genes in cutaneous HPVs without damaging host cells.
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Low dose of hydroxychloroquine is associated with reduced COVID-19 mortality: study
A new study provides observational evidence that low-dose hydroxychloroquine is associated with reduced COVID-19 mortality in hospitalized patients, particularly those with severe illness, when administered within the first week of symptoms.
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Epidemiology, achievements, and challenges in the elimination of hepatitis B in China
A new review outlines China’s progress towards meeting the World Health Organization (WHO) hepatitis B virus 2030 elimination targets, identifies persistent gaps, and highlights strategies for achieving HBV elimination.
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Scientists find flawed data in recent study relevant to coronavirus antiviral development
A new study shows why scientists still don’t know how the NiRAN domain works. The findings could have sweeping implications for drug developers already working to design antivirals based on flawed assumptions, and underscore the importance of rigorous validation.
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T cells take aim at Chikungunya virus
A new study offers the first-ever map of which parts of Chikungunya virus trigger the strongest response from the body’s T cells, bringing researchers closer to developing Chikungunya vaccines or therapies that harness T cells to strike specific targets to halt infection.
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Hep E virus can live out entire life cycle in kidney cells
Scientists have succeeded in proving in cell culture that hepatitis E viruses can infect kidney cells and can multiply with their help. The entire replication cycle of the virus takes place in kidney cells in the same way as in liver cells, their study shows.
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The gut’s secret weapon: viruses that heal
A comprehensive new review reveals how gut viruses interact with gut bacteria and host immunity, highlighting their roles in conditions like inflammatory bowel disease, colorectal cancer, and C. difficile infection. The findings offer a compelling case for harnessing the virome in novel therapies to reshape gut ecology and restore health.
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Engineers develop electrochemical sensors for cheap, disposable diagnostics
Electrodes coated with DNA could enable inexpensive tests with a long shelf-life, which could detect many diseases and be deployed in the doctor’s office or at home.
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Novel flu vaccine adjuvant improves protection against influenza viruses, study finds
Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus challenges when combined with a mucosal adjuvant that enhances the body’s immune response, according to a study.