All Viruses articles – Page 3
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NewsEnhanced inner ear tropism of Adeno-Associated Virus (AAV) vectors via peptide display on AAV1 capsid
Researchers improving efficiacy of AAV)-mediated gene therapy for the inner ear screened and inserted short peptide motifs onto the surface of the AAV1 capsid. These engineered vectors achieved markedly higher transduction rates in inner ear hair cells and supporting cells.
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NewsBiomarkers indicating higher liver cancer risk in chronic hepatitis B patients identified
Researchers have identified Hepatitis B RNA serum levels as a biomarker that more accurately stratifies risk of liver cancer in individuals who have been functionally cured of chronic hepatitis B.
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NewsImaging technique is step towards needed treatments for hantaviruses in new molecular ma
Researchers have produced a detailed blueprint, the highest resolution yet, for a protein complex the Andes virus uses to infect host cells. The new detailed structural information enabled the researchers to produce a vaccine candidate that caused mice to produce neutralizing antibodies against the Andes virus.
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NewsProtein interplay offers insights into how the immune system recognizes viral RNA
A new study reveals how two proteins cooperate in a key early step of antiviral detection. Using cryo-electron microscopy and high-speed atomic force microscopy, researchers found that LGP2 binds to viral RNA and recruits MDA5 molecules, as if threading beads on a string.
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NewsScientists uncover mechanism used by three bacteria-killing viruses to target transporter
Biochemists have homed in on an underexplored small transporter called MurJ that is a vital part of the pathway bacteria use to build their chain-mail-like cell wall. Using advanced tools, the scientists have determined the common mechanism used by three different bacteria-killing viruses to block MurJ from doing its job.
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NewsDiffering immune responses in infants may explain increased severity of RSV over SARS-CoV-2
Reseachers report that the two respiratory viruses trigger different immune responses. Those differences might explain why these two diseases have different clinical outcomes and require different treatment strategies.
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NewsCOVID-19 infection predicts higher risk of kidney disease, study finds
Researchers have found that previous COVID-19 infection is a significant risk factor for kidney disease. Compared to influenza, those with a history of COVID-19 infection have a 2.3-times higher risk of acute kidney injury and a 1.4-times higher risk of chronic kidney disease, according to an analysis of over three million patients.
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NewsHPV vaccination provides “sustained protection” against cervical cancer
Human papillomavirus (HPV) vaccination is associated with a significantly reduced risk of invasive cervical cancer, with no indication of waning protection up to 18 years after vaccination, finds a study.
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NewsSingle daily pill shows promise as replacement for complex, multi-tablet HIV treatment regimens
A phase 3 clinical trial has shown that a new, daily oral tablet that combines two current HIV treatment medications – bictegravir and lenacapavir (BIC/LEN) – may simplify treatment significantly for people with HIV who currently take very complex treatments.
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NewsStudy reveals key differences in long-term brain effects of COVID-19 and flu
While both Covid and flu can leave lasting lung damage, only SARS-CoV-2 infection caused persistent brain inflammation and small blood vessel injury, even after the virus was no longer detectable, a new study has found.
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NewsNew strategies aim at HIV’s last strongholds
A new study has overcome a long-standing challenge—how to isolate and study elusive HIV-infected cells called authentic reservoir clones (ARCs) that evade the immune system, making the disease difficult to cure.
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NewsA parasitic origin for the ribosome?
Scientists propose that the ribosome first emerged from a proto-ribosome, likely a viral parasite, which began by taking advantage of proto-cells, and ended up being incorporated into cells, at some time before the last universal common ancestor.
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News Huayunuo approval positions China at forefront of viral hepatitis innovation, says GlobalData
Huahui Health has recently secured conditional approval from China for Huayunuo (Libevitug Injection), marking it as the first domestically developed monoclonal antibody (mAb) drug for chronic hepatitis D virus (HDV) infection in adults with or without compensated cirrhosis.
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NewsHoly Grail: One vaccine may provide broad protection against many respiratory infections and allergens
In a new study in mice, researchers have developed a universal vaccine formula that protects against a wide range of respiratory viruses, bacteria and even allergens.
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NewsNew findings on infection with the Epstein-Barr virus
Researchers have identified genetic and non-genetic factors that help the body fight the Epstein-Barr virus. Using a new technique, they were able to estimate the amount of EBV in the blood and find correlations in large health data sets – for example, an increased viral load in people with HIV infections, but also in smokers.
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NewsMissed opportunity: Study shows low vaccination rates among expectant mothers in Norway against COVID-19 and influenza
A study of over 50,000 pregnant women in Norway during the 2023/24 influenza season found that only 29.9% were vaccinated against influenza and 12.1% against COVID-19 during pregnancy, remaining far below recommended targets.
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NewsNewly discovered virus linked to colorectal cancer
Researchers have discovered a previously undescribed virus in a common gut bacterium, Bacteroides fragilis. The virus appears more frequently in patients with colorectal cancer.
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NewsNew review points to faster, safer vaccine development
A new review examines viral mimic systems that reproduce key features of dangerous pathogens such as SARS-CoV-2, the virus that causes Covid-19, without the ability to replicate or cause disease. These systems allow researchers to study infection safely, quickly, and in a wider range of laboratories.
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NewsA ring to transcribe them: The unique path of poxviruses
A study shows for the first time the mechanical elegance with which the viral protein VITF-3 controls the transcription process. Vaccinia viruses, the most widely studied model viruses from the poxvirus family, were examined at the molecular level.
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NewsExposing a hidden anchor for HIV replication
Scientists investigating HIV have revealed a previously unknown role for the viral protein integrase, which helps HIV insert itself into human DNA. A new study provides the first direct evidence that integrase plays a critical structural role earlier on in HIV’s life cycle — when the virus matures into an infectious force.