All Viruses articles – Page 3
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Scientists uncover critical role of membrane protein topology in beta-coronaviruses assembly
Beta-coronaviruses, including SARS-CoV-2, have caused global health problems. How the virus infects host cells and triggers immunological responses has been investigated extensively. However, how the virus replicates and assembles in the cell is largely unknown. Researchers at the Institute of Biophysics, Chinese Academy of Sciences, have uncovered a conserved mechanism ...
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Therapeutic vaccine for chronic hepatitis B enters first clinical trial in patients
TherVacB, a novel therapeutic vaccine for chronic hepatitis B, has entered its first clinical trial in patients. A successful phase 1a trial in healthy volunteers saw the vaccine demonstrate a favorable safety profile and trigger the desired immune responses.
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High-efficacy adjuvanted subunit vaccine against variant infectious bursal disease virus in chicks
Infectious bursal disease (IBD) is an acute, highly contagious disease caused by the infectious bursal disease virus (IBDV), primarily affecting chicks. Notably, the emergence of new mutant strains that exacerbate the disease can cause serious economic losses to the global poultry industry. To date, there is no commercial vaccine against ...
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Study of water bodies frequented by wild birds reveals presence of antimicrobial resistance genes in nine in 10 samples
The first UK study to monitor antimicrobial resistance and influenza viruses in water bodies has revealed that 92% of samples contained genes for resistance to colistin, an antibiotic of last resort.
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New study in Ukraine indicates significant lifetime exposure and ongoing transmission of hepatitis B and C viruses among the general population
A nationwide study in Ukraine has found evidence of significant exposure to hepatitis B and C viruses and substantial ongoing circulation among the population, highlighting need for immunisation and regular screening.
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Immunity to seasonal flu protects against severe illness from bird flu in ferrets
A study in ferrets — which have remarkably similar respiratory systems to humans — suggests that widespread immunity to H1N1 seasonal influenza virus may explain why exposure to H5N1 bird flu causes only mild symptoms in humans.
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New study brings vaccine hopes for deadly Nipah virus
Researchers have tested experimental Nipah vaccines in pigs, aiming to cut off the virus at one of its key transmission routes. The study describes the development of three vaccine candidates using different viral surface proteins.
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Scientists uncover how ticks defend themselves against a deadly virus
Researchers studying ticks’ cellular responses to Severe Fever with Thrombocytopenia syndrome virus pinpointed how two RNA helicases, essential proteins found in all forms of life, were critical in reducing SFTSV’s replication within the ticks.
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How does infection with respiratory syncytial virus affect the health of older adults?
Adults aged 65 and older hospitalized for RSV in Ontario experienced significantly higher rates of adverse outcomes such as longer length of hospital stay, transfer to intensive care, and 30-day mortality, compared with patients hospitalized with influenza, urinary tract infection, or fracture.
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Vitamin D deficiency increases risk of COVID-19 hospitalization
Experts say it’s not just booster shots that could offer protection against Covid-19 – healthy levels of vitamin D may also play a role. Researchers found a clear link between low vitamin D levels and an increased risk of being hospitalised by the virus.
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Co-infections in young bats could underpin coronavirus emergence
A new study finds that young bats are infected more frequently by coronaviruses and could be a key source of viral spillover into other species. It also reveals the dynamics of coronaviruses circulating in Australian bats, which pose no known risk to humans.
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How AI can enhance early detection of emerging viruses: study
Coupling wastewater surveillance and a newly developed AI algorithm can help public health organizations more quickly predict potential outbreaks, a new study suggests.
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Study identifies world-first treatments to prevent a life-threatening virus infection
A study found two HIV antivirals already on the market can suppress transmission of HTLV-1 in humanised mice and prevent disease. When used in combination with a compound that induces cell death, infected cells were killed – flagging a potential future curative strategy.
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New jab protects babies from serious lung infection, study shows
Vaccination of pregnant women has been linked to a drop in newborns being admitted to hospital with a serious lung infection, research suggests.
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Epidemiology: Key predictors of avian flu outbreaks in Europe identified
Several local factors — including the minimum temperature reached in autumn, the water level in lakes and ponds in winter, and the presence of mute swans — could be key for predicting the potential of an outbreak of highly pathogenic avian flu (HPAI) occurring in Europe.
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Virologists issue warning on rapidly escalating measles crisis in the U.S. and worldwide
The Global Virus Network (GVN) is sounding the alarm over a sharp resurgence of measles cases in the United States and globally. This resurgence, fueled by falling vaccination rates, threatens to erode decades of public health progress.
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Study suggests some maternal HIV infections may be missed during pregnancy
Newborns exposed to HIV during pregnancy or birth should receive antiretroviral medication immediately after delivery - but a study finds more than half of infants diagnosed with HIV in their first year of life had not received this essential postnatal treatment.
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Omicron strain BA.2.86 emergence ‘defies natural explanation’
A researcher investigating the origin of the BA.2.86 lineage found that sporadic cases were identified in multiple, geographically distant locations around the world during its initial appearance in the summer of 2023.
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Avian flu has major economic costs for dairy industry
A new paper shows that the highly pathogenic avian influenza H5N1 virus causes severe mastitis and decreased milk production in dairy cows, a drop-off that may extend beyond the clinical outbreak period.
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RNA viruses may differentially shape carbon recycling in the ocean
A new study has uncovered that certain ocean viruses—specifically RNA viruses—may disrupt how carbon and nutrients are recycled in the ocean, potentially altering the global carbon cycle.