All Viruses articles – Page 10
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Tunnel-building virus: How Zika transmits from mother to fetus
For the first time, researchers demonstrated the component involved in the tunneling nanotubes built by Zika virus to infect placental cells, an infection mechanism which is unique to the Zika virus alone.
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Current antivirals likely less effective against severe infection caused by bird flu virus in cows’ milk
Scientists found that in a preclinical model, two FDA–approved flu antivirals generally did not successfully treat severe H5N1 infections. Meanwhile, the route of infection, whether through the eye, the nose or the mouth, significantly impacts effectiveness.
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Metagenomic analysis of tick-borne viruses in Inner Mongolia
A new study maps the landscape of TBVs in Inner Mongolia, but also highlights the potential spillover risk of TBVs. These findings underscore the urgent need for One Health strategies for monitoring emerging TBVs at the tick-human-livestock interface in northern China.
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NIH-sponsored trial of Lassa vaccine opens
A National Institutes of Health (NIH)-sponsored clinical trial of a candidate vaccine to prevent Lassa fever has begun enrolling participants at the University of Maryland School of Medicine, Baltimore.
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Epstein-Barr virus worsens ulcerative colitis by triggering macrophage pyroptosis through glycolysis
The study shows that EBV infection activates pyroptosis in intestinal macrophages by upregulating glycolysis. This process leads to the release of pro-inflammatory cytokines, which further damage the intestinal barrier and worsen colitis symptoms.
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COVID-19 pandemic worsened mother and infant birth outcomes
Mothers who became pregnant after the start of the pandemic, those who experienced moderate-to-severe infections during pregnancy, and those who had infections during the third trimester were more likely to have adverse outcomes.
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Study finds new targets needed for vaccine to prevent herpesvirus transmission to babies
Despite the lack of research on vaccines against congenital cytomegalovirus (CMV), a research has recently discovered that the virus is able to cause cross-placental transmission even with the absence of multple essential proteins, providing insights for future vaccine development.
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Older adults might be more resistant to bird flu infections than children
Previous exposures to seasonal flu strains could prime the immune system to produce antibodies against the current version of H5N1 avian influenza virus in older adults, whilst children would benefit more from H5N1 vaccinations.
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First coronavirus similar to MERS is found in bats in South America
A novel coronavirus, which shares high genetic similarities with MERS-CoV, was identified in bats in the state of Ceará, Brazil. Experiments to find out whether it can infect humans are set to take place in collaboration with Hong Kong University.
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COVID-19 discovery opens door to new treatments for chronic lung problems
A discovery was made to understand how severe viral infections, like COVID-19 and flu could destroy the ability of immune cells to repair the tissue damage in lungs, causing long COVID and other chronic lung diseases.
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Researchers develop method to identify dormant cells that carry HIV
A new method is developed that utilizes a fluorescent genetic switch to tag and trace the lineages of the HIV-infected cells, including the dormant ones. This system might help to develop target therapies for the infected immune cells.
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Careers
My autistic academic maze - and my advice to neurodiverse PhD students
In Neurodiversity Celebration Week, PhD student Joshua Yates reveals the challenges of pursuing a career in microbiology with autism and dyslexia - and his advice to others.
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Symptoms of long-COVID can last up to two years after infection with COVID-19
According to a study of the COVICAT cohort, almost one in four people infected with SARS-CoV-2 suffered from long-COVID. In more than half of them the symptoms persisted for two years.
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Tecovirimat is safe but ineffective as treatment for clade II mpox
The antiviral drug tecovrimat used without other antivirals did not reduce the time to clinical resolution of clade II mpox lesions or improve pain control among adults in an international clinical trial.
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Drug may prevent COVID-19 in exposed people within households, major trial finds
An international clinical trial of the oral antiviral drug, ensitrelvir, which has been proved to prevent COVID-19 cases, was conducted and found to be very effective. The drug will be awaiting for approval before becoming widely available.
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Cause of post-COVID inflammatory shock in children identified
MIS-C is a serious inflammatory shock that affects children and can occur several weeks after a COVID infection. Researchers have found that reactivation of a pre-existing, dormant infection with the Epstein-Barr virus triggers an excessive inflammatory response.
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Measles on the rise again in Europe: Time to check your vaccination status
Eight out of ten people who were diagnosed with measles in the EU/EEA in the last year were not vaccinated, according to a new measles and rubella update.
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Researchers announce breakthrough in next-generation polio vaccines
Researchers have taken a major step towards producing a more affordable and lower-risk polio vaccine using virus-like particles (VLPs). These particles mimic the outer protein shell of poliovirus, but are empty inside.
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New study highlights gaps in HPV-related cancer prevention for people living with HIV
A new study reveals gaps in knowledge surrounding the prevention of HPV-related cancers in people living with HIV and outlines future research priorities. It highlights existing disparities in healthcare for this vulnerable population.
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Intranasal herpes infection may produce neurobehavioral symptoms, study finds
A new study finds that herpes infection through the nose can lead to anxiety, motor impairment and cognitive issues. The research is the first to show that, by exploiting a cellular enzyme, the virus can produce behavioral symptoms.