All Viruses articles – Page 4
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NewsStudy reveals common mutation linked to autoimmune diseases may protect people from viral infections
New research shows a “risk gene” linked to higher odds of developing autoimmune diseases such as diabetes or lupus may also provide a survival advantage fighting viral infections like coronavirus. The gene PTPN22 carries a mutation, 1858C>T (R620W), found in roughly one in 10 people in North America.
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NewsCRISPR system inhibits hepatitis E virus
Researchers have developed a novel antiviral concept - using the CRISPR/Cas13 system, they were able to specifically suppress the replication of the hepatitis E virus in human cells.
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NewsAndes hantavirus outbreak: ECDC working on the frontline to support EU Member States
Genomic information also shows that the virus involved in the outbreak is similar to Andes viruses already known to circulate in South America, and is not a new variant. There is currently no evidence that this variant spreads more easily or causes more severe disease than other Andes viruses.
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NewsResearchers track the mutations that allow HIV-1 to escape broadly neutralizing antibodies
Scientists have established the most comprehensive view to date of how HIV-1 can escape broadly neutralizing antibodies. They have discovered viral mutations that make HIV-1 strains resistant to two bNAbs, 3BNC117 and 10-1074.
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NewsUKHSA update on the hantavirus cruise ship outbreak
The UK Government has announced it has worked with international partners to ensure the safe return of all remaining British nationals on board the MV Hondius, with passengers now safely transferred to Arrowe Park Hospital.
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NewsExpanded tuberculosis screening does not speed up treatment initiation or improve survival in hospitalized patients with HIV
According to the EXULTANT trial, adding molecular tests on sputum, urine and stool samples does not appear to outperform the standard WHO-recommended diagnostic approach.
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NewsAnti-CRISPR stops the protein assembly line in bacteria
Bacteria fend off invading viruses with molecular scissors that slice up viral DNA, but viruses can fight back with a molecular trick that stops the scissors from ever being made. A viral “anti-CRISPR” protein sits on the ribosome and jams it as a CRISPR protein named Cas12 begins to form.
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NewsScientists take crucial step in developing world’s first measles treatment
Scientists have characterized human antibodies capable of neutralizing measles virus. These antibodies bind to key sites on measles virus and prevent the virus from entering host cells.
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News‘Atomic snapshots’ of proofreading enzyme could lead to better COVID-19 drugs
A research team used images generated by a cryogenic electron microscope (cryo-EM) to observe the interplay between SARS-CoV-2 proofreading enzyme exoribonuclease (ExoN) and RNA incorporated with antivirals such as remdesivir, sofosbuvir and bemnifosbuvir.
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NewsNeedle-free flu vaccine aims to boost children’s immunity
A new study will explore the effects of a nasal spray flu vaccine on children’s immune systems, aiming to boost future protection and lower vaccine hesitancy rates.
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NewsSeasonal COVID-19 vaccination in 2025/26 reduced risk of illness by half in Canada
An interim analysis estimates that the COVID-19 vaccine for the 2025/26 season reduced the risk of illness in Canada by about half at about 9 weeks after vaccination, offering protection beyond the vaccine’s target strain.
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NewsLong-term dynamic virological response patterns and clinical outcomes in hepatitis B virus-related cirrhosis
The long-term clinical outcomes of patients with hepatitis B virus (HBV)-related cirrhosis receiving nucleos(t)ide analog (NA) therapy according to virological response patterns remain inadequately defined. A new study aimed to investigate the association between virological response patterns and clinical outcomes.
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NewsScientists use ultrasound to destroy influenza A and COVID-19 viruses without damaging human cells
Researchers have discovered that high-frequency ultrasound waves similar to those used in medical exams can eliminate viruses such as SARS-CoV-2 and H1N1 without damaging human cells. Acoustic resonance causes structural changes in viral particles until they rupture and become inactivated.
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NewsNew kind of CRISPR could treat viral infection and cancer by shredding sick cells’ DNA
A new technology uses a relative of the CRISPR-Cas9 gene editing system to kill target cells. When activated by a specific, programmable genetic target, the Cas12a2 protein rips a cell’s genome apart. Researchers programmed Cas12a2 to kill virus-infected cells or cancer cells while leaving healthy cells untouched.
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NewsScientists discover how HIV hijacks a cellular ‘gateway’ to infect resting immune cells
New research reveals that when HIV spreads directly between T-cells it triggers a molecular signalling chain that temporarily ‘unlocks’ the nuclear pore complex, allowing the HIV virus and capsid to enter and integrate into the host’s DNA.
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NewsResearchers flip the CRISPR script to develop world’s first DNA-guided gene editing tool for precise infectious disease diagnosis
A research team has successfully developed the world’s first DNA-guided CRISPR-Cas system capable of programmable RNA targeting and cleavage. This breakthrough overturns the conventional CRISPR paradigm, which uses RNA as a guide to target DNA.
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NewsResearchers uncover hidden health risks from urban airborne microbes
Researchers have discovered that seemingly insignificant microbial components in the air, including bacteria, fungi, viruses and cellular debris, pose a long-overlooked health hazard. Bacterial endotoxins can trigger inflammatory responses in the human respiratory system in nearly 20% of cases.
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NewsDairy farms in California may transmit H5N1 virus through multiple sources
A new study suggests that avian influenza (H5N1) is transmitted through multiple, previously unknown sources on dairy farms and that some H5N1 positive cows do not show clinical signs of infection.
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NewsClimate change increases spillover risk of rodent-borne arenaviruses
Climate change is likely to drive rodent-borne arenaviruses into parts of South America that have never faced these diseases, according to an early risk projection model that incorporated climate projections, shifting rodent populations and the risks of human infection.
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NewsResearchers advance phage therapy in fight against antimicrobial resistance
Scientists have uncovered how Mycobacterium abscessus can evade bacteriophage therapy, and demonstrated a combination strategy to overcome this resistance, offering a pathway towards more effective and durable treatments.