All oncolytic viruses articles
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NewsResearchers combine bacteria and viruses to demonstrate a new way to fight cancer
Researchers have designed non-toxic Salmonella bacteria to deliver viruses that are safe to humans but potent against liver and pancreatic cancer tumors. Animal models treated with this combination of bacteria and viruses saw almost all their tumors eliminated and lived significantly longer.
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NewsTrial tests virus-immunotherapy combination for neuroendocrine tumors
A phase I clinical trial is testing whether a tumor-targeting virus can help immunotherapy work more effectively against aggressive neuroendocrine tumors that often resist treatment. The ongoing study has completed its first three dose levels with no severe treatment-related side effects reported to date.
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NewsVirus-based therapy boosts anti-cancer immune responses to brain cancer
A study has shown that a single injection of an oncolytic virus—a genetically modified virus that selectively infects and destroys cancer cells—can recruit immune cells to penetrate and persist deep within brain tumors.
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NewsRoute of entry for Semliki Forest virus into the brain revealed, yielding brain cancer treatment hope
Researchers have shown that the Semliki Forest virus enters the central nervous system by first entering the cerebrospinal fluid and binding to a specific cell type before penetrating deeper into the brain, potentially tagging the virus as an agent for treating brain cancer.
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NewsOncolytic virus inhibits liver cancer growth by inducing cell cycle arrest and apoptosis
Researchers have found that administration of an oncolytic virus, Senecavirus A, effectively suppressed hepatocellular carcinoma proliferation and growth in a mouse model placed beneath the skin by triggering apoptosis.
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NewsCombining virus therapy with radiation to fight brain cancer works better than either treatment alone
Combining a cancer-targeting virus with radiation to treat brain cancer in mice was more effective than either therapy on its own, according to new research, providing hope for new treatments that combine immunotherapy with traditional surgery, chemotherapy or radiation.
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NewsViruses that kill cancer cells show promise for triple-negative breast cancer when combined with chemo
Researchers have shared positive results from a phase 2 clinical trial of an oncolytic virus combined with standard chemotherapy in patients with early stage triple-negative breast cancer.