All SARS-CoV-2 articles
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Peptide acts as molecular shield to prevent SARS-CoV-2 from infecting cells
The synthetic peptide was inspired by ACE2, the protein to which the virus that causes COVID-19 binds to invade human cells. The results point to a route for the development of novel antivirals.
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New mouse models offer valuable window into COVID-19 infection
Scientists have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19 because their cells were engineered to include two important human molecules that are involved in infection of human cells.
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High-throughput modular click chemistry synthesis of catechol derivatives to target Covid protease
Researchers performed high-throughput synthesis of catechol derivatives from the bioactive catechol-terminal alkyne scaffold A4, by using modular click chemistry, in a bid to target the Covid virus’s 3C-like protease (3CLpro).
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$12 million grant to research how vaccines induce lasting immunity
Researchers have received a $12 million grant to study how vaccines trigger long-lasting immune responses. The work may inform the design of new, more protective vaccines for respiratory viruses, including SARS-CoV-2 and influenza.
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Study IDs novel small-molecule inhibitors of SARS-CoV-2 with chemical genetics
A new article discusses the identification of novel small-molecule inhibitors of SARS-CoV-2 by chemical genetics.
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Covid’s ORF10 hijacking ubiquitination machinery reveals potential unique drug targeting sites
A new study discusses how SARS-CoV-2 ORF10 hijacking ubiquitination machinery reveals potential unique drug targeting sites.
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Study charts spectrum of febrile rash illness in China from 2009 to 2021
A new study monitors the spectrum of viral pathogens involved in febrile rash illness (FRI) and their epidemiology.
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Analysis sheds light on COVID-19-associated fungal disease in Japan
Researchers in Japan pored through data to understand the incidence in Japan of COVID-19-associated pulmonary aspergillosis (CAPA), a severe invasive fungal infection of the lungs.
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New testing system using Janus particles rapidly and accurately detects COVID-19
Researchers have developed a new quantitative testing system called the ’Express Biochecker’, which provides a simple, rapid, and low-cost method for detecting the coronavirus N protein.
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Origami paper sensors could help early detection of infectious diseases in low-cost test
Researchers have developed an innovative new method for identifying biomarkers in wastewater using origami-paper sensors, enabling the tracking of infectious diseases using the camera in a mobile phone.
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Genetic tracing at the Huanan Seafood market supports COVID animal origins
A study provides a list of the wildlife species present at the market from which SARS-CoV-2 most likely arose in late 2019, based on a new analysis of metatranscriptomic data released by the Chinese Center for Disease Control and Prevention (CDC).
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Low-power laser can selectively detect coronavirus spike proteins in just five minutes
Researchers have demonstrated a method to detect the presence of viruses quickly, using only a small sample. The light-induced immunoassay coated with novel coronavirus spike proteins was highly sensitive even with weak light like a laser pointer.
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Antiviral-resistant variants of SARS-CoV-2 can emerge in immunocompromised people
Individuals with compromised immunity and persistent COVID-19 infections can harbor drug-resistant variants of the SARS-CoV-2 virus, which have the potential to spread to the general population.
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Study sheds light on how virus-fighting cells develop during long Covid
A new long-term study into long COVID has investigated how a certain population of white blood cells, called memory T cells, are established and develop as part of the body’s defense to fight off the disease.
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US COVID-19 rates show oscillating waves every six months
COVID-19 cases in the U.S. have shown unexpected oscillating waves every six months between the southern states and the northern states and, to a lesser degree, from east to west, according to new research.
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Scientists discover dual roles of antibodies in COVID-19 infections
A new study has discovered an antibody that can both assist and block a virus. This particular antibody helps pre-Omicron variants of the virus infect cells while preventing the Omicron variant from doing the same.
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It’s the unchanging parts of the Covid virus we also need to pay attention to, study suggests
A new study demonstrates the value of surveillance for public health initiatives, while identifying stable parts of the virus as potential candidates for small molecule drugs and other drug development.
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Scientists deploy sound waves as acoustic tweezers to separate viruses from saliva
Researchers have described a platform that uses sound waves as acoustic tweezers to sort viruses from other compounds in a liquid. In demonstrations, the method quickly and accurately separates viruses from large and small particles in human saliva samples.
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Study uncovers the specialized immune cells that fight COVID-19
A team of researchers from Osaka University has pinpointed the B cells responsible for boosting COVID-19 immunity after vaccination.
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New study provides insight to why Covid vaccines hit some harder than others
Scientists have highlighted factors that may explain why some people perceived more side effects from the SARS-CoV2 vaccine than others, including stress, exercise, and use of hormonal birth control.