All smallpox articles
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NewsResearchers develop machine learning model to predict virus reservoirs
A new artificial intelligence tool could aid in limiting or even prevent pandemics by identifying animal species that may harbor and spread viruses capable of infecting humans.
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NewsStudy evaluates airborne transmission risk of mpox compared to COVID-19 and smallpox
Scientists have found that the inhaled infectious dose of mpox is at least 100 times lower than that of SARS-CoV-2 and smallpox, making efficient respiratory aerosol transmission highly unlikely in its current form - but future viral evolution could alter this dynamic.
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NewsResearchers review strategies for the modification of vaccinia virus towards a better vaccine vector
A new review delineates the commonly targeted viral genes for attenuation during vaccinia virus (VACV) vector modification and provides an overview of the progress in VACV-vectored vaccine development.
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NewsPotential single-dose smallpox and mpox vaccine moves forward
Scientists report on studies suggesting that the horsepox virus in the experimental vaccine is substantially more attenuated—and less likely to trigger a systemic infection—than the vaccinia virus used in the single-dose vaccine already approved by the FDA.
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NewsStudy reveals isolation, endogamy and pathogens in early medieval Spanish community
An archaeogenetic study sheds new light on the isolated medieval community Las Gobas in northern Spain. The researchers have identified the variola virus which can offer a new explanation on how smallpox entered Iberia.
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NewsStudy reveals how the immune system fights to keep herpes at bay
A recent study, conducted using lab-engineered cells, unveils the precise maneuvers used by host and herpes simplex virus (HSV) in the fight for dominance of the cell.
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FeaturesThe pandemic potential of poxvirus infections
What can the causes of ancient pandemics, smallpox and viral evolution tell us about future threats?
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NewsNew monkeypox study increases fear of potential escalation in central Africa
A new study of monkeypox infections in a remote area of the Democratic Republic of the Congo (DRC) shows transmission rates rising closer to the point where outbreaks are likely to be larger and more frequent.
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NewsResearchers identify compounds that inhibit monkeypox virus replication
Researchers from Boston University Chobanian & Avedisian School of Medicine have developed a novel compound that soon could be used to protect against all tested poxviruses that cause human disease, including monkeypox.