All Trinity College Dublin articles
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NewsThe link between the gut microbiome and autism is not backed by science, researchers say
There’s no scientific evidence that the gut microbiome causes autism, a group of scientists argue in an opinion paper. They warn that conclusions that supported this hypothesis are undermined by flawed assumptions, small sample sizes, and inappropriate statistical methods.
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NewsNew nasal vaccine has potential to transform respiratory disease prevention
Researchers have demonstrated that their nasally-delivered, antibiotic-inactivated Bordetella pertussis (AIBP) vaccine not only prevents severe disease but also curbs bacterial transmission — an achievement long sought by vaccine developers worldwide.
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NewsCould targeted steroid use offer a universal complimentary treatment to fight TB?
Newly published research provides evidence that treating patients with steroids may enhance the function of their macrophages to kill the mycobacteria, while diminishing pathways of inflammatory damage.
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NewsHeatwaves greatly influence parasite burden; likely spread of disease
New research implies that heatwaves have a major influence on the spread of many diseases – and that many existing predictive models have overlooked this complexity. Differences in heatwaves can increase disease burden by up to 13 times in an animal model.
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NewsBNT162b2 vaccine not only targets COVID-19 virus, but may also help control innate inflammation
New findings suggest the BNT162b2 vaccine may reduce the production of pro-inflammatory mediators to bacterial, fungal or viral infections by reprogramming innate immune cells to regulate inflammation.
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NewsThe role of understudied dysfunctional immune cells in severe COVID-19: new research
A new study focuses on understanding how ‘notoriously understudied’ immune cells behave abnormally in patients with severe COVID-19 and provides insights into mechanism behind COVID-19 disease progression.
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NewsScientists discover new process to drive anti-viral immunity
Scientists have discovered a new process in our immune systems that leads to the production of an important family of anti-viral proteins called interferons.
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NewsWild birds’ health and likely survival is affected by the gut microbiome
Researchers have found that the gut microbiome affects the health of wild birds, which could impact their survival rates and ultimately population sizes.
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NewsScientists pinpoint new drug target for RSV
Scientists have discovered how the dangerous Respiratory Syncytial Virus (RSV) defuses our immune response and, in doing so, they have pinpointed an exciting new target for drug developers.
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NewsScientists discover how to improve vaccine responses to potentially deadly bacterium
Researchers have shown in an animal model that targeting a key suppressive immune molecule (IL-10) during the delivery of a vaccine improves the ability of the vaccine to protect against infection.
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NewsResearchers uncover new reasons to target neutrophils for tuberculosis therapy
Using cell models of infection, scientists examined the cross-talk between two lung immune cells: the macrophage and the neutrophil.
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NewsResearchers develop material that reduces bacterial infection and speeds up bone healing
Researchers have developed a new surgical implant that has the potential to transform the treatment of complex bone infections.
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NewsNew bacterial blueprint will help fight antibiotic resistance
Scientists have gained high-res structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it and thus suppress disease-causing bacteria.
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NewsToothpaste made with salivary enzyme teams with xylitol to defeat oral microbes
Toothpaste made with a salivary enzyme shows high antimicrobial activity when teamed with xylitol - and is even more effective than the gold standard antimicrobial, chlorhexidine.
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CareersAMI internship leads Zoe down path of antimicrobial resistance
Zoe Dunphy undertook a lab internship in 2020 in Trinity College Dublin’s microbiology department, funded by an AMI Summer Studentship Grant. She reveals how that experience has developed her work on AMR.