All tuberculosis articles – Page 3
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Experts developing immune-enhancing therapies to target tuberculosis
Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body’s own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.
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Undernourished household members at increased risk for developing TB after exposure
Researchers have found that undernourished household contacts are three times more likely to progress to TB disease.
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Researchers uncover new reasons to target neutrophils for tuberculosis therapy
Using cell models of infection, scientists examined the cross-talk between two lung immune cells: the macrophage and the neutrophil.
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Tuberculosis can have a lasting impact on the lung health of individuals who have been successfully treated for the disease
New research has found compelling evidence that tuberculosis (TB) can have a lasting impact on the lungs of individuals who have been successfully treated for the disease.
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Collaboration garners new support to tackle high-value tuberculosis targets
A groundbreaking collaboration will combat global health challenges in tuberculosis through innovative technology.
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Study finds association between TB infection and increased risk of various cancers
A population-wide observational study shows an association between tuberculosis (TB) and cancer, with those with current or previous TB more likely to have a diagnosis of a variety of cancers.
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More than 18,000 excess TB cases in the U.S. attributable to structural racism
A robust analysis of national tuberculosis (TB) surveillance data found continuing, persistent disparities in TB incidence among U.S.-born racial and ethnic minorities, despite an overall decrease in cases observed during the analysis period.
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A combination of approved drugs enhances the delivery of anti-bacterial medications to treat tuberculosis
Scientists repurposed approved drugs that they originally tested to normalize blood vessels surrounding tumors to improve drug delivery to cancer cells.
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New enzymatic cocktail can kill tuberculosis-causing mycobacteria
A new study shows that an enzymatic cocktail can kill a variety of mycobacterial species of bacteria, including those that cause tuberculosis.
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Cancer therapies show promise in combating tuberculosis
A study has identified a combination of medications that may improve blood flow within granulomas, tight clusters of white blood cells formed by the body’s immune system in response to tuberculosis infection, benefiting drug delivery.
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New classification of tuberculosis supports efforts to eliminate the disease
A new way to classify tuberculosis (TB) that aims to improve focus on the early stages of the disease has been presented by an international team.
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Researchers ask if active screening for tuberculosis among vulnerable populations is cost-effective
Scientists present the findings of their systematic review on active pulmonary TB screening programmes run between 2008 and 2023 in so-called high-risk groups living in low TB incidence countries.
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No persistent cough in 4 out of 5 with tuberculosis
A study of more than 600,000 individuals shows that 80% with TB have no persistent cough, previously believed to be the most common symptom of the infectious disease.
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Research links prison time with increase of TB
New research finds that being in prison or being a former prisoner is responsible for high rates of multidrug resistant (MDR) TB.
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Phages help to identify people at risk of developing TB
A novel approach to studying the progression of tuberculosis (TB) from infection to disease has identified and treated people at increased risk of developing the disease that current methods of testing would not.
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Exposure to Mycobacterium seems to remodel immune response against TB
A collaborative team has uncovered how prior exposure to bacteria changes the lung’s innate immune response - and what it might mean for vaccines.
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People in prison are at very high risk of tuberculosis, even years after release
A study in Paraguay evaluates tuberculosis incidence during and after incarceration in a cohort of nearly 3,000 people.
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Nutritional acquired immunodeficiency (N-AIDS) is the leading driver of the TB pandemic
Acknowledging N-AIDS as a key determinant and comorbidity of TB can enhance the ability to detect, prevent and eliminate TB, a new review suggests.
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Single gene could be crucial for persistence in TB bacteria
Researchers have uncovered an important mechanism that allows the tuberculosis (TB) bacterium to persist in the human host for decades.
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TB cases in humans tens of thousands of years earlier than previosuly detected
Recent research suggests that the emergence of tuberculosis infection in human populations dates back tens of thousands of years earlier than previously known cases in the Middle East.