All tuberculosis articles – Page 3
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New classification of tuberculosis supports efforts to eliminate the disease
A new way to classify tuberculosis (TB) that aims to improve focus on the early stages of the disease has been presented by an international team.
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Researchers ask if active screening for tuberculosis among vulnerable populations is cost-effective
Scientists present the findings of their systematic review on active pulmonary TB screening programmes run between 2008 and 2023 in so-called high-risk groups living in low TB incidence countries.
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No persistent cough in 4 out of 5 with tuberculosis
A study of more than 600,000 individuals shows that 80% with TB have no persistent cough, previously believed to be the most common symptom of the infectious disease.
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Research links prison time with increase of TB
New research finds that being in prison or being a former prisoner is responsible for high rates of multidrug resistant (MDR) TB.
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Phages help to identify people at risk of developing TB
A novel approach to studying the progression of tuberculosis (TB) from infection to disease has identified and treated people at increased risk of developing the disease that current methods of testing would not.
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Exposure to Mycobacterium seems to remodel immune response against TB
A collaborative team has uncovered how prior exposure to bacteria changes the lung’s innate immune response - and what it might mean for vaccines.
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People in prison are at very high risk of tuberculosis, even years after release
A study in Paraguay evaluates tuberculosis incidence during and after incarceration in a cohort of nearly 3,000 people.
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Nutritional acquired immunodeficiency (N-AIDS) is the leading driver of the TB pandemic
Acknowledging N-AIDS as a key determinant and comorbidity of TB can enhance the ability to detect, prevent and eliminate TB, a new review suggests.
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Single gene could be crucial for persistence in TB bacteria
Researchers have uncovered an important mechanism that allows the tuberculosis (TB) bacterium to persist in the human host for decades.
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TB cases in humans tens of thousands of years earlier than previosuly detected
Recent research suggests that the emergence of tuberculosis infection in human populations dates back tens of thousands of years earlier than previously known cases in the Middle East.
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Nanoparticles with antibacterial action shorten duration of tuberculosis treatment
A low-cost technology involving nanoparticles loaded with antibiotics and other antimicrobial compounds that can be used in multiple attacks on infections by the bacterium responsible for most cases of tuberculosis has been developed.
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Novel compounds promise success in the fight against tuberculosis and depression
Scientists have shown that a specific polyprenylated polycyclic acylphloroglucinol, PPAP53, is able to activate human macrophages to fight resistant tuberculosis bacteria without being toxic to the macrophages themselves.
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Drug-resistant tuberculosis may be under-diagnosed, reveals genomic analysis
This genomic sequencing study, in southern Mozambique, is the first to characterise the drug resistance profile at the population level and identify mutations that escape routine diagnostic tests.
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Blood glycerol levels linked to tuberculosis severity in Type 2 Diabetes
A study has uncovered that elevated glycerol levels are responsible for increased severity of tuberculosis (TB) disease in experimental models with Type 2 diabetes (T2D).
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Researchers develop a new TB vaccine testing model by leveraging old BCG vaccine
Each year, tuberculosis (TB) kills more people than any other infectious disease, falling out of the top spot only temporarily during the COVID-19 pandemic. Source: Saint Louis University Daniel Hoft, M.D., Ph.D., director of the Saint Louis University Center for Vaccine Development Despite TB’s wide reach and ...
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Cancer therapy shows promise against tuberculosis
A promising new cancer therapy also appears extremely potent against one of the world’s most devastating infectious diseases: tuberculosis (TB).
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Researchers invent single, rapid test for both HIV and TB
Scientists have developed a new and rapid test that can detect both HIV and tuberculosis at the same time with just a small amount of blood.
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New dawn in the fight against TB
UNITE4TB, the largest public-private collaboration in tuberculosis drug development, announces the start of clinical trials.
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New research points out ways to improve tuberculosis vaccines
A new study unveils a previously unappreciated role for a class of immune cells in the early stages of tuberculosis (TB) infection.
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Super sensitive method detects deadly infectious diseases
Rutgers researchers have developed a way of detecting the early onset of deadly infectious diseases using a test so ultrasensitive that it could someday revolutionize medical approaches to epidemics.
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