All tuberculosis articles
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NewsUS funding cuts could result in nearly 9 million child tuberculosis cases, 1.5 million child deaths
A new study projects that US funding cuts to global health aid will have a catastrophic effect on pediatric TB, with children in Sub-Saharan Africa and Southeast Asia likely to experience a spike in preventable cases and deaths over the next decade.
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NewsCould targeted steroid use offer a universal complimentary treatment to fight TB?
Newly published research provides evidence that treating patients with steroids may enhance the function of their macrophages to kill the mycobacteria, while diminishing pathways of inflammatory damage.
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NewsNew global burden of disease study: Mortality declines, youth deaths rise, widening health inequities
The world faces an emerging crisis of higher death rates in adolescents and young adults in North America and Latin America due to suicide and drug and alcohol consumption, and in sub-Saharan Africa due to infectious diseases and unintentional injuries.
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NewsCattle vaccine immunity ‘boost’ tested by new research
Scientists at Aberystwyth University are leading research into how a widely used vaccine can boost overall immunity in livestock. The four-year study will investigate the concept of ‘trained immunity’ – a form of immune memory triggered by a vaccine.
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NewsNew CRISPR test could make tuberculosis screening as simple as a mouth swab
Researchers have developed an enhanced CRISPR-based tuberculosis test that works with a simple tongue swab, a potential breakthrough that could allow easier, community-based screenings for the world’s deadliest infectious disease.
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NewsNew ‘cough simulator’ mimics TB transmission with unprecedented accuracy
Researchers have developed a new experimental system called Transmission Simulation System (TSS) that replicates the airborne transmission of TB – by simulating the human cough – with unparalleled realism and never-before-seen precision.
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NewsNew AI tool reveals how drugs kill tuberculosis
A new study offers a powerful AI-assisted method for uncovering exactly how TB drugs kill the bacteria, opening the door to smarter treatment combinations that could work faster.
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NewsSeventy-year-old Parkinson’s drug shows promise against tuberculosis
A medication developed in the 1950s to treat Parkinson’s disease may offer a powerful new tool in the fight against tuberculosis. The study found that benztropine can dramatically reduce levels of TB-causing bacteria by boosting the body’s natural immune response.
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NewsSkin test reagent proves effective and safe for TB diagnosis in children
A new class of skin test reagents based on Mycobacterium tuberculosis (MTB)-specific antigens has been developed. A phase III clinical trial suggests that C-TST is an effective and safe option for diagnosing pediatric TBI.
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NewsIn hard-to-treat form of tuberculosis, shorter, gentler therapy shows unequal benefit
A first-ever clinical trial exclusively conducted among people with a hard-to-treat form of tuberculosis known as pre-extensively drug-resistant TB shows many patients benefit from shorter, simpler regimens.
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NewsTB bacteria play possum to evade vaccines
Scientists studied how the TB bacterium evades an immune system primed to destroy it. Their genetic study in mice reveals that TB bacteria can essentially play dead to outlast the immune response.
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NewsNew breakthrough uncovers how to kill ‘zombie’ TB cells resistant to antibiotics
Researchers exposed a library of over 500,000 genetically modified tuberculosis bacteria to two commonly used antibiotics. By analysing the survivors, they pinpointed genes whose disruption significantly reduced the number of surviving persisters.
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NewsMultiple testing for infectious diseases among migrants key to cutting onward transmission
Routine testing for multiple infectious diseases among migrants will benefit healthcare systems by identifying key infections earlier, a new study finds.
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NewsStudy uncovers how certain antibodies help fight tuberculosis
Researchers collected the largest library of monoclonal antibodies to Mycobacterium tuberculosis (Mtb) and identified specific antibody features that significantly limit its growth.
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NewsBiologist examines growth patterns in bacteria to help develop more targeted, effective antibiotics
Among the new investigative projects at the University of Texas at Arlington is one headed by Dr. Cara Boutte, who is studying how certain bacteria grow by examining how they build their cell walls, an effort that could lead to the development of more effective antibiotics.
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NewsStudy discovers DNA switch that controls TB growth – and could help unlock its antibiotic resistance secrets
The bacteria that cause tuberculosis (TB) may have an ‘on-off switch’ that lets them pause and restart growth, according to a new study which helps explain why TB is so hard to treat with antibiotics and could pave the way for better drugs.
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NewsTuberculous meningitis: study shows that metabolism drives mortality
A new study suggests that dysregulated β-oxidation may be an important and potentially modifiable contributor to mortality in tuberculous meningitis.
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NewsThe Global Fund to fight AIDS, Tuberculosis and Malaria ‘should step up efforts’
The international community must protect global responses to HIV, tuberculosis (TB), and malaria to serve humanity’s collective interests, according to a new opinion article.
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NewsNew molecular label could lead to simpler, faster tuberculosis tests
Chemists have demonstrated that they can label a glycan called ManLAM using an organic molecule that reacts with specific sulfur-containing sugars. These sugars are found in only three bacterial species, including the microbe that causes TB.
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NewsA new smartphone-sized device can test for tuberculosis - here’s why that matters for children
Scientists have designed the first-of-its-kind portable device to deliver fast, low-cost TB results — no lab required — to fight the world’s deadliest infectious disease.