All tuberculosis articles
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NewsStudy maps how tuberculosis bacteria power themselves
A new study provides the first detailed 3D structure of a protein called EtfD, which the bacterium Mycobacterium tuberculosis uses to extract energy from lipids (fats), along with the first laboratory test capable of directly measuring its activity.
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NewsTackling tuberculosis systematically: How the environment shapes TB risk
Researchers introduce the concept of the “tuberculogenic environment”: the complex interplay of structures, rules, and living conditions that keep certain communities at high TB risk, even when care is available.
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NewsRich medieval Danes bought graves ‘closer to God’ despite leprosy stigma, archaeologists find
Researchers used gravesites to investigate social exclusion based on illness, by studying whether people with leprosy or tuberculosis were kept out of the higher-status areas. Unexpectedly, they found that people who were ill with stigmatized diseases were buried just as prominently as their peers.
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NewsResearchers develop new inhalable treatment for TB
Researchers have developed an inhalable, immunomodulating, biocompatible nanoparticle system encapsulating rifampin, one of the most important TB drugs.
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NewsShorter treatment regimens are safe options for preventing active tuberculosis
A study comparing one- and three-month antibiotic treatments to prevent active tuberculosis (TB) finds that a high percentage of patients successfully completed both regimens and suffered few adverse side effects.
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NewsSepsis study IDs simple ways to save lives in Africa
Tuberculosis (TB) is a major unrecognized cause of deadly sepsis among people with HIV in Africa, a new study reveals. It found that more than half of the hundreds of patients enrolled in the study had TB and that immediate treatment increased their chances of survival significantly.
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NewsTB and HIV treatments are not enough for a full recovery
Existing treatments control TB and HIV, but the immune system does not revert to normal, helping explain why people living with HIV remain susceptible to infections and underscoring the need for immunotherapies.
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NewsReal-world data gives Africa a smarter path to fighting HIV and TB
African biostatisticians have offered a powerful, data-driven alternative that can accurately inform HIV policy, reduce healthcare costs, and save more lives.
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NewsNew one-two punch could knock out drug-resistant TB
Researchers found that pairing the antibiotic rifampicin with a second compound turned multidrug resistance into a weakness—providing proof of concept for using basic science to design life-saving dual-drug strategies.
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NewsCould hidden infections be fueling long COVID?
For millions suffering from long COVID, their persistent breathlessness, brain fog and fatigue remain a maddening mystery, but microbiologists think they may have cracked the case. The review argues that co-infections acquired before or during COVID could cause symptoms to persist indefinitely for many people.
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NewsTuberculosis: Scientists develop novel drug candidate for combating resistant pathogens
Researchers have developed a promising new substance for targeting bacteria that cause tuberculosis. The team have produced a compound that inhibits the pathogens’ ability to produce energy and causes them to die.
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News‘Creeping catastrophe’: Climate change is driving global rise in infectious diseases, leading health experts warn
Infectious diseases such as malaria, dengue, and tuberculosis are considered to pose as great a challenge to global health as new or emerging pathogens, according to a study. Participants reported that climate change, poverty, and drug resistance are combining to create an escalating health crisis.
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NewsPhase 2 clinical trial results show potential to shorten TB treatment time
New clinical trial results show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve tuberculosis (TB) treatment when combined with pretomanid and linezolid in a treatment regimen known as “SPaL.”
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NewsScientists uncover tuberculosis bacterium’s ’heartbeat’, opening door to new treatments
Scientists have identified a molecular system inside Mycobacterium tuberculosis that functions like the organism’s heart or lungs, keeping it alive. The system, known as PrrAB, helps the bacterium generate energy and breathe. When researchers used a gene-silencing tool, the bacterium died.
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NewsNew study finds targets for a new tuberculosis vaccine
A large-scale screen of tuberculosis proteins has revealed several possible antigens that could be developed as a new vaccine for TB, the world’s deadliest infectious disease.
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NewsUS funding cuts could result in nearly 9 million child tuberculosis cases, 1.5 million child deaths
A new study projects that US funding cuts to global health aid will have a catastrophic effect on pediatric TB, with children in Sub-Saharan Africa and Southeast Asia likely to experience a spike in preventable cases and deaths over the next decade.
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NewsCould targeted steroid use offer a universal complimentary treatment to fight TB?
Newly published research provides evidence that treating patients with steroids may enhance the function of their macrophages to kill the mycobacteria, while diminishing pathways of inflammatory damage.
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NewsNew global burden of disease study: Mortality declines, youth deaths rise, widening health inequities
The world faces an emerging crisis of higher death rates in adolescents and young adults in North America and Latin America due to suicide and drug and alcohol consumption, and in sub-Saharan Africa due to infectious diseases and unintentional injuries.
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NewsCattle vaccine immunity ‘boost’ tested by new research
Scientists at Aberystwyth University are leading research into how a widely used vaccine can boost overall immunity in livestock. The four-year study will investigate the concept of ‘trained immunity’ – a form of immune memory triggered by a vaccine.
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NewsNew CRISPR test could make tuberculosis screening as simple as a mouth swab
Researchers have developed an enhanced CRISPR-based tuberculosis test that works with a simple tongue swab, a potential breakthrough that could allow easier, community-based screenings for the world’s deadliest infectious disease.