All tuberculosis articles – Page 4
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Nanoparticles with antibacterial action shorten duration of tuberculosis treatment
A low-cost technology involving nanoparticles loaded with antibiotics and other antimicrobial compounds that can be used in multiple attacks on infections by the bacterium responsible for most cases of tuberculosis has been developed.
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Novel compounds promise success in the fight against tuberculosis and depression
Scientists have shown that a specific polyprenylated polycyclic acylphloroglucinol, PPAP53, is able to activate human macrophages to fight resistant tuberculosis bacteria without being toxic to the macrophages themselves.
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Drug-resistant tuberculosis may be under-diagnosed, reveals genomic analysis
This genomic sequencing study, in southern Mozambique, is the first to characterise the drug resistance profile at the population level and identify mutations that escape routine diagnostic tests.
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Blood glycerol levels linked to tuberculosis severity in Type 2 Diabetes
A study has uncovered that elevated glycerol levels are responsible for increased severity of tuberculosis (TB) disease in experimental models with Type 2 diabetes (T2D).
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Researchers develop a new TB vaccine testing model by leveraging old BCG vaccine
Each year, tuberculosis (TB) kills more people than any other infectious disease, falling out of the top spot only temporarily during the COVID-19 pandemic. Source: Saint Louis University Daniel Hoft, M.D., Ph.D., director of the Saint Louis University Center for Vaccine Development Despite TB’s wide reach and ...
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Cancer therapy shows promise against tuberculosis
A promising new cancer therapy also appears extremely potent against one of the world’s most devastating infectious diseases: tuberculosis (TB).
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Researchers invent single, rapid test for both HIV and TB
Scientists have developed a new and rapid test that can detect both HIV and tuberculosis at the same time with just a small amount of blood.
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New dawn in the fight against TB
UNITE4TB, the largest public-private collaboration in tuberculosis drug development, announces the start of clinical trials.
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New research points out ways to improve tuberculosis vaccines
A new study unveils a previously unappreciated role for a class of immune cells in the early stages of tuberculosis (TB) infection.
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Super sensitive method detects deadly infectious diseases
Rutgers researchers have developed a way of detecting the early onset of deadly infectious diseases using a test so ultrasensitive that it could someday revolutionize medical approaches to epidemics.
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Cattle may face much higher TB risk from indirect interactions with wildlife
Cattle face a hypothetically high risk of getting tuberculosis from wildlife - such as deer, foxes, and wild boar - through indirect interactions, with a much lower risk from direct interactions, a new study suggests.
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New VDEC is ‘step change’ for UK’s growing vaccine capabilities
The UK Health Security Agency has unveiled its world-leading Vaccine Development and Evaluation Centre at Porton Down, which will be at the forefront of the UK’s ability to develop vaccines against the world’s deadliest pathogens.
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Study demonstrates efficacy of new short-term resistant TB treatment
Four patients at Boston Medical Center (BMC) Tuberculosis Clinic were cured of MDR TB with a six-month regimen that included bedaquiline, pretomanid and linezolid (BPaL).
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Investigational three-month TB regimen is safe but ineffective
The first clinical trial of a three-month tuberculosis (TB) treatment regimen is closing enrollment because of a high rate of unfavorable outcomes with the investigational course of treatment.
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Nearly half of TB cases in prisons worldwide go undetected
In the first global assessment of tuberculosis among incarcerated people, a new study found consistently high TB case rates and low case detection in prisons.
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Consortium awarded €9M to create better tuberculosis vaccine
Researchers from the University of Leicester are among those hoping to create an improved vaccine to fight tuberculosis as part of a €9 million Euro project.
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BCG vaccine found ineffective against COVID-19 in healthcare workers
An international trial investigating the potential immune-boosting effects of the tuberculosis BCG vaccine against COVID-19 found that the risk of developing the disease during the first six months after vaccination was not reduced in participants as originally hoped for.
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BCG does not protect health workers against Covid
A world-leading international trial into the immune boosting benefits of the tuberculosis vaccine, BCG, has found it does not protect healthcare workers against COVID-19.
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International consensus highlights importance of molecular testing for AMR in TB management
A multidisciplinary group of tuberculosis experts from the TBnet and RESIST-TB networks have reached a consensus on key issues related to the molecular prediction of Mycobacterium tuberculosis antibiotic sensitivity or resistance and its clinical implications.
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Scientists use non-virulent strain to expose weaknesses in drug-resistant TB
Researchers have discovered new ways to treat antibiotic-resistant strains of tuberculosis (TB), opening the door to new approaches for tackling the disease that kills about 4,000 people a day.