All tuberculosis articles – Page 5
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NewsPhages help to identify people at risk of developing TB
A novel approach to studying the progression of tuberculosis (TB) from infection to disease has identified and treated people at increased risk of developing the disease that current methods of testing would not.
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NewsExposure to Mycobacterium seems to remodel immune response against TB
A collaborative team has uncovered how prior exposure to bacteria changes the lung’s innate immune response - and what it might mean for vaccines.
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NewsPeople in prison are at very high risk of tuberculosis, even years after release
A study in Paraguay evaluates tuberculosis incidence during and after incarceration in a cohort of nearly 3,000 people.
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NewsNutritional acquired immunodeficiency (N-AIDS) is the leading driver of the TB pandemic
Acknowledging N-AIDS as a key determinant and comorbidity of TB can enhance the ability to detect, prevent and eliminate TB, a new review suggests.
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NewsSingle gene could be crucial for persistence in TB bacteria
Researchers have uncovered an important mechanism that allows the tuberculosis (TB) bacterium to persist in the human host for decades.
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NewsTB cases in humans tens of thousands of years earlier than previosuly detected
Recent research suggests that the emergence of tuberculosis infection in human populations dates back tens of thousands of years earlier than previously known cases in the Middle East.
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NewsNanoparticles with antibacterial action shorten duration of tuberculosis treatment
A low-cost technology involving nanoparticles loaded with antibiotics and other antimicrobial compounds that can be used in multiple attacks on infections by the bacterium responsible for most cases of tuberculosis has been developed.
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NewsNovel compounds promise success in the fight against tuberculosis and depression
Scientists have shown that a specific polyprenylated polycyclic acylphloroglucinol, PPAP53, is able to activate human macrophages to fight resistant tuberculosis bacteria without being toxic to the macrophages themselves.
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NewsDrug-resistant tuberculosis may be under-diagnosed, reveals genomic analysis
This genomic sequencing study, in southern Mozambique, is the first to characterise the drug resistance profile at the population level and identify mutations that escape routine diagnostic tests.
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NewsBlood glycerol levels linked to tuberculosis severity in Type 2 Diabetes
A study has uncovered that elevated glycerol levels are responsible for increased severity of tuberculosis (TB) disease in experimental models with Type 2 diabetes (T2D).
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NewsResearchers develop a new TB vaccine testing model by leveraging old BCG vaccine
Each year, tuberculosis (TB) kills more people than any other infectious disease, falling out of the top spot only temporarily during the COVID-19 pandemic. Source: Saint Louis University Daniel Hoft, M.D., Ph.D., director of the Saint Louis University Center for Vaccine Development Despite TB’s wide reach and ...
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NewsCancer therapy shows promise against tuberculosis
A promising new cancer therapy also appears extremely potent against one of the world’s most devastating infectious diseases: tuberculosis (TB).
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NewsResearchers invent single, rapid test for both HIV and TB
Scientists have developed a new and rapid test that can detect both HIV and tuberculosis at the same time with just a small amount of blood.
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NewsNew dawn in the fight against TB
UNITE4TB, the largest public-private collaboration in tuberculosis drug development, announces the start of clinical trials.
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NewsNew research points out ways to improve tuberculosis vaccines
A new study unveils a previously unappreciated role for a class of immune cells in the early stages of tuberculosis (TB) infection.
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NewsSuper sensitive method detects deadly infectious diseases
Rutgers researchers have developed a way of detecting the early onset of deadly infectious diseases using a test so ultrasensitive that it could someday revolutionize medical approaches to epidemics.
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NewsCattle may face much higher TB risk from indirect interactions with wildlife
Cattle face a hypothetically high risk of getting tuberculosis from wildlife - such as deer, foxes, and wild boar - through indirect interactions, with a much lower risk from direct interactions, a new study suggests.
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NewsNew VDEC is ‘step change’ for UK’s growing vaccine capabilities
The UK Health Security Agency has unveiled its world-leading Vaccine Development and Evaluation Centre at Porton Down, which will be at the forefront of the UK’s ability to develop vaccines against the world’s deadliest pathogens.
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NewsStudy demonstrates efficacy of new short-term resistant TB treatment
Four patients at Boston Medical Center (BMC) Tuberculosis Clinic were cured of MDR TB with a six-month regimen that included bedaquiline, pretomanid and linezolid (BPaL).
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NewsInvestigational three-month TB regimen is safe but ineffective
The first clinical trial of a three-month tuberculosis (TB) treatment regimen is closing enrollment because of a high rate of unfavorable outcomes with the investigational course of treatment.