All tuberculosis articles – Page 2
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NewsStudy identifies ‘Achilles heel’ of drug-resistant pathogens
A study has found a highly vulnerable weakness in drug-resistant Mycobacterium tuberculosis, using a genetic platform to identify biological pathways in a drug-resistant strain of the bacterium that are highly sensitive to inhibition.
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NewsResearchers seek out shorter, simpler TB treatments
Scientists are working to develop treatment options for tuberculosis that require fewer pills, shorter treatment periods (ideally 2-3 months), and consist of 3-4 medications that reduce the risk of resistance while minimizing toxicity.
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News10% of children in high-burden tuberculosis settings may develop the disease by age 10
A new study finds a high risk of tuberculosis infection and disease in children up to 10 years old who live in areas where TB spread is common.
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NewsTuberculosis changes liver metabolism and could promote diabetes
Scientists have discovered that tuberculosis disrupts glucose metabolism in the body and can promote progress to diabetes.
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NewsBetter use of vaccines could reduce antibiotic use by 2.5 billion doses annually, says WHO
A new report finds that vaccines against 24 pathogens could reduce the number of antibiotics needed by 22% or 2.5 billion defined daily doses globally every year, supporting worldwide efforts to address antimicrobial resistance (AMR).
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NewsStudy identifies potential novel drug to treat tuberculosis
A new study demonstrates that a novel semi-synthetic compound can be derived from natural compounds to produce potent activity against Mycobacterium tuberculosis, including multi-drug resistant strains.
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NewsPlant compound used in traditional medicine may help fight tuberculosis
A compound found in African wormwood — a plant used medicinally for thousands of years to treat many types of illness — could be effective against tuberculosis, according to a new study.
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NewsResearchers discover mechanism driving immune perturbations after severe TB infections
Rsearchers have discovered a mechanism that drives the long-term decline in immune response that is observed after tuberculosis (TB) has been successfully treated.
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NewsPromising TB therapy safe for patients with HIV
A therapy showing promise to help control tuberculosis (TB) does not interfere with combined antiretroviral therapy (cART), according to new research.
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NewsStudy finds outbreak detection under-resourced in Asia
A two-year assessment provides critical insights and recommendations for strengthening genomic sequencing for infectious disease surveillance in 13 South and Southeast Asian countries.
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NewsNew findings on TB could change how we treat inflammatory disorders
Researchers have found rare mutation that leaves its carriers much more likely to become ill with TB—but, curiously, not with other infectious diseases, potentially upending long-held assumptions about the immune system.
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NewsImmune protection against tuberculosis reinfection driven by cells that dampen lung inflammation
The body’s first line of defense against tuberculosis (TB) involves immune cells that suppress lung inflammation instead of activating it, scientists report.
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NewsNIH grant establishes UAB’s Global Research Resource for Human Tuberculosis
A $5.8m grant led by Adrie Steyn, Ph.D., of the University of Alabama at Birmingham and the Africa Health Research Institute, or AHRI, in Durban, South Africa, will provide user-requested infected human lung tissue and analytical services to tuberculosis researchers worldwide.
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NewsStudy highlights factors associated with higher tuberculosis risk in South Africa
Tuberculosis is the world’s top infectious killer. About 10 million people fall ill with the disease every year, and roughly 1.5 million people die because of it, according to the World Health Organization. Additionally, about one-quarter of the world’s population is infected with the disease’s causative agent Myctuberobacterium tuberculosis. ...
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NewsShared geographic origin of TB strain and human host could boost risk of infection
For some forms of tuberculosis, the chances that an exposed person will get infected depend on whether the individual and the bacteria share a hometown, according to a study comparing how different strains move through mixed populations in cities.
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NewsScientists ID ‘unconventional’ new pathway for TB vaccines
Marginal zone B (MZB) cells are a natural response to TB infection which has been long overlooked - and which might be a welcome new target.
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NewsNIH funds consortium to accelerate development of new TB treatments
A new consortium has been awarded a five-year, $31 million grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to accelerate the development of faster, more effective treatment regimens for tuberculosis.
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NewsEdited BCG offers potential vaccine to prevent tuberculosis in people of all ages
TB remains the leading cause of death by infectious disease globally, with South Africa having one of the highest incidence rates in the world. Source: Y tambe Apparatus for BCG vaccination - Kuchiki’s needle While the BCG vaccine used to prevent TB is widely available for infants, ...
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NewsScientists can now detect antibiotics in your fingerprints – aiding the fight against drug-resistant TB
A fingerprint may soon be all a doctor needs to check whether tuberculosis patients are taking their antibiotics – thanks to a new study. Scientists successfully detected the drugs in finger sweat – and with almost the same accuracy as a blood test.
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NewsGlobal study reveals stark differences between females and males in major causes of disease burden
Globally, there are substantial differences between females and males (aged 10 and older) when it comes to health, with limited progress in bridging these health gaps over the past 30 years, according to a new study.