All USA & Canada articles – Page 74
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Research lays groundwork for a lifesaving vaccine for bacterium that threatens newborns
Researchers are unraveling the workings of Streptococcus agalactiae infections, which could someday lead to a vaccine.
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RSV shown to infect nerve cells, causing inflammation and damage
Long thought to only infect the respiratory tract, RSV has been found to infect nerve cells, cause nerve damage and enter the spinal cord, potentially granting access to the central nervous system.
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War on bugs can’t be won, researchers declare
A new paper calls for antimicrobial resistance to be reframed as a sustainability issue.
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New NIH-funded center could soon reduce the need for pharmaceutical trials on animals
The University of Rochester will house a new national center focused on using tissue-on-chip technology to develop drugs more rapidly and reduce the need for animal trials.
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Scientists uncover role of helper MLRs in tomato immune response to pathogen attack
An innovative study delves into the intricate defense mechanisms of tomatoes against the notorious bacterial pathogen, Pseudomonas syringae pv. tomato (Pst).
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Sickle cell raises COVID-19 risk, but vaccination lags
Adults with sickle cell disease around half as likely to have had initial doses as people without sickle cell disease, a study in Michigan shows.
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Potential nasal COVID-19 vaccine candidate offers better and longer protection
Study shows that administering a COVID-19 vaccine as a nasal spray rather than a subcutaneous injection enhances the body’s long-term immune memory, thereby increasing the vaccine’s overall effectiveness.
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Crop spray could lead to mass resistance in new-generation antifungal treatments
An agricultural fungicide approved in the US and currently under consideration by authorities worldwide could have a devastating effect on a new drug for one of world’s deadliest infectious diseases.
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Zika virus is effective when used to treat a type of childhood cancer in mice
Injecting neuroblastoma tumors with Zika virus shrank or eliminated those tumors in studies with mice, suggesting that the virus could someday serve as an effective cancer therapy, according to a new study.
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Novo Nordisk Foundation partners with CARB-X to fight drug-resistant infections
The Novo Nordisk Foundation is committing up to $25 million to support the early-stage development of innovative tools to prevent, diagnose and treat the most dangerous drug-resistant bacterial infections. The three-year grant will go to the Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X), the leading global non-profit public-private partnership in this ...
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Researchers decode the ‘cytokine storm’ in sepsis
The team found that three cytokine pairs were responsible for most of the body’s damaging response to sepsis.
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COVID-19 vaccine strongly effective for children and adolescents during delta and omicron
Children and adolescents who received one of the main COVID-19 vaccines were significantly protected and showed no increased signs of cardiac complications compared to young people who were not vaccinated.
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Researchers discover molecular ‘barcode’ used by bacteria to secrete toxins
Researchers have discovered a molecular “barcode” system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.
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Researchers unmask an old foe’s tricks to thwart new diseases
Researchers are studying Yersinia pestis, the bacterium that causes bubonic and pneumonic plague, to better understand its ability to evade the immune system and apply that understanding to control other pathogens.
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New approach could address antibiotic resistance to Mycobacterium abscessus
Scientists have designed new versions of the drug spectinomycin that overcome efflux, the main mechanism driving resistance.
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Soil fungi may help explain the global gradient in forest diversity
Mycorrhizal fungi appear to be counteracting the effects of harmful soil pathogens in ways that influence global patterns of forest diversity.
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Researchers identify why cancer immunotherapy can cause colitis
Studies in mice reveal the mechanism that induces this severe side effect and point to a solution that kills the cancer without causing gastrointestinal issues.
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Novel compound protects against infection by virus that causes COVID-19
Compounds that obstruct the “landing gear” of a range of harmful viruses can successfully protect against infection by the virus that causes COVID-19.
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Calibr announces license agreement with Gilead to develop long-acting HIV antiviral agent
Long-acting combination HIV regimens have the potential to transform the future of coordinated HIV clinical care
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Single-point testing could miss cases of asymptomatic malaria
Dynamic, fluctuating levels of this parasite in people without symptoms argues against single-point testing to diagnose infections, a new study suggests.