All USA & Canada articles – Page 95
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Nearly half of TB cases in prisons worldwide go undetected
In the first global assessment of tuberculosis among incarcerated people, a new study found consistently high TB case rates and low case detection in prisons.
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Immune-boosting therapy helps honey bees resist deadly viruses
Scientists have successfully tested a novel way of boosting honey bees’ immune systems to help them fend off deadly viruses, which have contributed to the major losses of the critical pollinator globally.
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CRISPR-like system in eukaryotes can edit the human genome
The first RNA-guided DNA-cutting enzyme found in eukaryotes, Fanzor could one day be harnessed to edit DNA more precisely than CRISPR/Cas systems.
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Nanoparticle may improve mRNA cancer vaccines
Tests in mice with melanoma and colon cancer show the tiny particle creates an ‘army’ of immune cells that carry vaccine’s instructions, say the researchers.
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Molecular insights may inform new treatments for drug-resistant TB
Researchers have used state-of-the-art imaging to examine two new compounds that target ATP synthase, potentially stopping TB bacteria from producing the energy they need to survive.
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Squash bugs devour each other’s poo to stock their microbiome
Researchers have found that, to acquire healthy gut bacteria, young squash bugs innately seek out and eat the faeces from older squash bugs.
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Digital test directly measures HIV viral load
Researchers have developed a time and cost-efficient digital assay that can directly measure the presence of HIV in a single drop of blood.
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Researchers can use ultrasound to control orientation of small particles, including bacteria
Using ultrasound technology and a nozzle, scientists have separated, controlled and ejected different particles based on their shape and various properties, with implications for drug delivery and bioprinting.
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Autism-specific metabolic pathways linked to gut microbes
A reanalysis of previous studies has identified autism-specific metabolic pathways associated with particular human gut microbes - these were also seen elsewhere in autistic individuals, from their brain-associated gene expression profiles to their diets.
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Researchers reveal how Leishmania parasite uses immune cells as Trojan Horse
A new study found that the parasite targets a receptor on the surface of the neutrophil to gain access to the cell, and once inside the parasite resists the neutrophils’ pathogen-killing molecules.
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Rule-breaking anoxic bacteria infected with viruses
Researchers investigating why green and purple bacteria in northeast Washington didn’t obey the usual rules found they had genes in their metagenome that came from viruses.
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Lupus flare-ups linked to Ruminococcus blautia gnavus blooms in gut
A new study found that bacterial blooms of the gut bacterium Ruminococcus blautia gnavus occurred at the same time as disease flare-ups in five of 16 women with lupus of diverse racial backgrounds studied over a four-year period.
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Complex life descended from common Asgardian ancestor
Researchers analyzing the genomes of hundreds of different archaea have discovered that eukaryotes trace their roots to a common Asgard archaean ancestor.
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DNA test could broaden access to cervical cancer screening
Researchers have devised a low-cost, point-of-care DNA test for HPV infections that could make cervical cancer screening more accessible in low- and middle-income countries.
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Feral cats shed more toxoplasmosis parasites in areas densely populated by humans
A new analysis suggests that wild, stray, and feral cats living in areas with higher human population density tend to shed a greater amount of the parasite that causes the disease toxoplasmosis.
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Combining virus therapy with radiation to fight brain cancer works better than either treatment alone
Combining a cancer-targeting virus with radiation to treat brain cancer in mice was more effective than either therapy on its own, according to new research, providing hope for new treatments that combine immunotherapy with traditional surgery, chemotherapy or radiation.
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Previously overlooked algae toxin widespread in Florida lagoon
A study of algae blooms and domoic acid finds a potential threat to the southern Indian River Lagoon’s ecosystem health.
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Molecule can block invasion of blood cells by malaria parasite
For the first time ever, a molecule able to prevent the invasion of blood cells by parasites of the genus Plasmodium, responsible for malaria, has been identified and described by scientists.
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Fungal infections are an unintended consequence of advanced immunotherapy
Researchers have shown how clinical use of some monoclonal antibodies may cause life-threatening systemic fungal infections.
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Probiotic could help mitigate mercury absorption in the gut
New research suggests that microbes in the human gut could be harnessed to block absorption of toxic metals like mercury and help the body absorb useful nutritional ones, like iron.