All virulence articles
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NewsA pan-sRNome analysis identifies novel regulatory small RNAs involved in Pseudomonas aeruginosa virulence
A characterization of nine newly discovered sRNAs reveals their regulatory networks in quorum sensing, biofilm formation, and interbacterial competition in Pseudomonas aeruginosa.
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NewsHow does a deadly chicken virus escape vaccines designed to slow it?
A new genome-wide study of the Marek’s disease virus identified 10 regions in the genome associated with what makes certain strains more virulent, and could inform next-generation vaccines.
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NewsDeadly superbug CR-hvKP: new framework says ‘watch virulence, not just resistance genes’
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) represents one of the most alarming evolutionary developments in modern infectious diseases—a “superbug” that combines high-level antibiotic resistance with enhanced virulence.
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NewsNew discoveries on genes involved in lysine biosynthesis and fungal virulence in Cryptococcus neoformans
A new study suggests that disrupting the lysine biosynthesis pathway represents a promising avenue for drug development against Cryptococcus neoformans, a fatal fungal meningitis pathogen.
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NewsResearchers develop experimentally validated AI model to predict the virulence of tomato yellow leaf curl virus
A research team has developed DeepTYLCV, an accurate and interpretable artificial intelligence model for predicting the virulence of Tomato Yellow Leaf Curl Virus (TYLCV). DeepTYLCV uses viral genome-derived sequence information, enabling the model to identify mild and severe strains before symptom-based confirmation.
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NewsIn mice, viruses gain virulence in some individuals, depending on genetics and sex
New research demonstrates that some hosts appear to serve as “evolutionary accelerators” that could enable viruses to gain virulence more quickly.
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NewsScientists uncover how pathogens switch on their virulence
A research team has uncovered how a key protein switches on the machinery that enables Leptospira pathogens to survive and cause disease. The findings provide new insights into how pathogens regulate their virulence and may open new avenues for therapeutic interventions.
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NewsNanoplastics can interact with Salmonella to affect food safety, study shows
Researchers investigating what happens when nanoplastics (polystyrene) interact with Salmonella discovered an increased expression of virulence-related genes. The bacteria also formed thicker biofilms, which indicates they are becoming more virulent.
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NewsChemical structures of surface polysaccharides from Acinetobacter baumannii for glycoconjugate vaccines
Researchers provided a comprehensive analysis of the molecules that make up the protective layer of complex sugars on the surface of Acinetobacter baumannii - known as capsular polysaccharides (CPS) and lipopolysaccharides (LPS), and essential for the bacterium’s virulence.
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NewsExperiment on joint NASA and SpaceX mission will study the effect of space travel on disease-causing bacteria
ARC/Sheba Medical Center is launching an Israeli experiment on the International Space Station to investigate how microgravity and space conditions influence bacterial virulence and antibiotic resistance.
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NewsScientists reveal what makes ‘bad’ bacteria life-threatening
Researchers have discovered that a mutation allows some E. coli bacteria to cause severe disease in people while other bacteria are harmless, a finding that could help to combat antibiotic resistance.
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NewsResearchers create safer form of Coxiella burnetii for scientific use
Scientists have unexpectedly discovered that the weakened form of the bacteria Coxiella burnetii (C. burnetii) not typically known to cause disease, has naturally acquired an ability to do so.
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NewsStudy reveals how drug resistant bacteria secrete toxins
Research suggests that reducing virulence in drug resistant infections rather than trying to kill bacteria outright may offer an answer to antimicrobial resistance.
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NewsResearch team unlocks the secrets to Strep A virulence
Researchers have unlocked one of the secrets as to why some forms of Strep A are associated with severe invasive infection.
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NewsStudy reveals how naturally-occurring compound kills major drug-resistant bacteria
Scientists analysing the effects of an organic compound on drug resistant bacteria have discovered how it can inhibit and kill Pseudomonas aeruginosa.