All The Microbiologist articles in Web Issue – Page 317
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NewsGSK and Fleming Initiative scientists unite to target AMR with advanced AI
GSK and the Fleming Initiative have announced six major new research programmes, called ‘Grand Challenges’ which harness some of the best scientific expertise and the latest technologies, including advanced AI, to find new ways to slow the progress of antimicrobial resistance (AMR).
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NewsBacteria ‘pills’ could detect gut diseases — without the endoscope
Researchers report that they’ve developed a sensor made of tiny microspheres packed with blood-sensing bacteria that detect markers of gastrointestinal disease. Taken orally, the miniature “pills” also contain magnetic particles that make them easy to collect from stool. Excreted from mouse models with colitis, the bacterial sensor detected gastrointestinal bleeding within minutes.
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NewsResearchers boost biosynthetic capacity in yeast through extended lifespan
Scientists have demonstrated that combining lifespan engineering strategies with metabolic pathway optimization in Saccharomyces cerevisiae enables highly efficient sclareol biosynthesis, marking an advance in improving microbial production through lifespan engineering.
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NewsGenetically engineered fungi are protein packed, sustainable, and taste similar to meat
Researchers used CRISPR to increase a fungus’s production efficiency and cut its production-related environmental impact by as much as 61%—all without adding any foreign DNA. The genetically tweaked fungus tastes like meat and is easier to digest than its naturally occurring counterpart.
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NewsImpact of pasteurization on dairy calves’ gut microbiota: A study of milk feeding and early microbial colonization
A new study highlights the impact of pasteurization on microbial diversity in dairy calves, underlining the importance of balancing pathogen safety and microbial health. It suggests that while pasteurization prevents pathogen transmission, it also reduces beneficial microbial transfer.
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NewsNew nanogel technology destroys drug-resistant bacteria in hours
A novel technology shows over 99.9% effectiveness against Pseudomonas aeruginosa (P. aeruginosa). It centres on a heteromultivalent nanogel: a flexible particle made by crosslinking polymers and adding sugar residues (galactose and fucose) alongside antimicrobial peptides.
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NewsStudy unveils structure, identification and characterization of the RibD-enolase complex in Francisella
A study aiming to identify anti-tularemia drug targets determined the atomic structure and identified its components of the native RibD-enolase protein complex in Francisella novicida.
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NewsSmart toilet designs in Cambodia held promise, but a key piece was missing
A smart toilet design introduced in rural Cambodia was supposed to change lives—keeping families safe and protecting the environment. However, while households reported that they liked the new system, a crucial piece was missing: using it correctly.
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NewsWorld’s largest metabolomic study completed, paving way for predictive medicine
UK Biobank has today released the final set of data on nearly 250 metabolites in half a million volunteers. This completes the world’s largest ever metabolomic study, which will help drive treatment strategies for neurological conditions, heart disease and cancer.
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NewsDrinking water people believe to be safe and clean often contain potentially dangerous bacteria
A study in Guatemala found the sources of drinking water people believe to be safe and clean often contain potentially dangerous bacteria. Bottled water sold in large refillable jugs was the most frequently contaminated with coliform bacteria – an indicator of fecal contamination.
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NewsScientists use computer model to improve hospitals’ ability to limit spread of drug-resistant infections
The computer model improves on traditional methods like contact tracing by inferring asymptomatic carriers in the spread of antibiotic-resistant infections.
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NewsResearchers diagnose disease with a drop of blood, a microscope and AI
Scientists have developed an automated, high-throughput system that relies on imaging droplets of biofluids for disease diagnosis in an attempt to reduce the number of consumables and equipment needed for biomedical testing.
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NewsMaternal health programme cuts infection deaths by 32%
A landmark multi-country clinical trial has shown that a structured, sustainable approach to infection prevention and treatment can save women’s lives, cutting severe maternal infections and deaths by about one-third (32%) compared to usual care.
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NewsLivestock manure linked to the rapid spread of hidden antibiotic resistance threats in farmland soils
Scientists have uncovered how even “low-risk” organic fertilizers like dried poultry manure can inadvertently drive a dramatic surge in dangerous antibiotic resistance genes, once released into vegetable plots used for food crops.
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NewsScientists develop world’s first modular co-culture platform for the one-pot production of rainbow-colored bacterial cellulose
The team engineered Komagataeibacter xylinus for bacterial cellulose synthesis and Escherichia coli for natural colorant overproduction. A co-culture of these engineered strains enabled the in situ coloration of bacterial cellulose.
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NewsThe road ahead: why conserving the invisible 99% of life is fundamental to planetary health
A new paper outlines how scientists came together to put together the first microbial conservation roadmap under the leadership of Applied Microbiology International President, Professor Jack Gilbert.
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NewsDiphtheria toxin fragment harnessed to fuse lipid vesicles at neutral pH
Researchers have discovered a novel way to fuse lipid vesicles at neutral pH. By harnessing a fragment of the diphtheria toxin, the team achieved vesicle membrane fusion without the need for pre-treatment or harsh conditions, opening the door to new applications.
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NewsThe road ahead: why conserving the invisible 99% of life is fundamental to planetary health
A new paper outlines how scientists came together to put together the first microbial conservation roadmap under the leadership of Applied Microbiology International President, Professor Jack Gilbert.
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NewsNew study finds higher levels of antimicrobial resistance (AMR) in surface water during winter
A new study has found that the levels of antimicrobial resistance (AMR) present in surface water increase during winter. Flooding, sewer overflows and agricultural run-off all contribute to a cocktail of pollutants that can increase AMR genes in surface water, potentially turning regular bugs into ‘superbugs’.
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NewsScientists reveal molecular cause behind “stuck” beer fermentation
Premature yeast flocculation (PYF) is a persistent issue in beer brewing, where yeast settles too early during fermentation. New research identifies multiple differential metabolites and confirmed galangin as a key factor that promotes early yeast aggregation.