All Asia & Oceania articles – Page 21
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New study reveals a safer alternative for long-term hepatitis B treatment
Researchers have studied the effects of switching from long-term tenofovir disoproxil fumarate to the antiviral besifovir dipivoxil maleatein (BSV) in patients with chronic hepatitis B. Switching to BSV may improve patient kidney and bone health.
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Rapid and accurate diagnosis of urinary tract infections using targeted next-generation sequencing
A study shows that tNGS demonstrates advantages in rapid and accurate UTI diagnosis, particularly in detecting polymicrobial infections and analyzing antibiotic resistance genes. It shows promise as an effective complementary tool for UTI diagnostics.
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Breaking antibiotic-resistant bacteria’s protective shields opens door for immune system response
Researchers have made progress in uncovering how Streptococcus pneumoniae constructs its capsule, which serves as a protective shield. This capsule is a primary target for vaccine development.
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Study evaluates airborne transmission risk of mpox compared to COVID-19 and smallpox
Scientists have found that the inhaled infectious dose of mpox is at least 100 times lower than that of SARS-CoV-2 and smallpox, making efficient respiratory aerosol transmission highly unlikely in its current form - but future viral evolution could alter this dynamic.
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Scientists ID natural products targeting SARS-CoV-2 - including caffeine
Researchers used computational methods to identify potential inhibitors of SARS-CoV-2 spike proteins, revealing promising natural compounds for guiding antiviral drug development, including caffeine.
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Green recipe: Engineered yeast boosts D-lactic acid production
An optimal combination of genetic “recipe” in a yeast strain achieves high yields of D-lactic acid production from methanol, advancing eco-friendly and sustainable biomanufacturing.
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Selective G6PDH inactivation for Helicobacter pylori eradication with transformed polysulfide
A new study highlights a novel mechanism of action driven by polysulfides, presenting a promising alternative strategy for combating H. pylori infections.
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Nature’s warriors: How rice plants detect and defend against viral invaders
A groundbreaking study uncovers a molecular mechanism by which rice cells perceive viral infections and initiate antiviral response, which significantly contributes to understanding of virus-host interactions for further disease resistance breeding.
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Efficacy of topical Nigella sativa L. with vinegar in the treatment of acne vulgaris
A team of researchers in India assessed the efficacy and safety of a topical formulation combining Kalonji and Sirka for the treatment of mild to moderate acne vulgaris. The formulation was compared with a 5% benzoyl peroxide.
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Japanese plant Daphne pseudomezereum yields anti-HIV daphnane diterpenoids
Scientists have discovered for the first time that Daphne pseudomezereum (commonly known as Onishibari) contains a substance inhibiting replication of human immunodeficiency virus (HIV).
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WHO calls for urgent action to address worldwide disruptions in tuberculosis services
Since World Tuberculosis Day is only days away, World Health Organization addresses the current challenges faced by countries in TB responses. They urgently call for an united global effort to combat the deadly disease and safeguard the public health from the devastating consequences.
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Updated guidelines for pediatric Mycoplasma pneumoniae infection
In light of the rise in antibiotic resistance, new guidelines are released with detailed recommendations of diagnosis and treatment strategies for pediatric Mycoplasma pneumoniae pneumonia (MPP), along with the means to manage severe complications.
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Hidden threat: The evolving fungus that spreads through cats and humans
Researchers have developed a better understanding about the molecular basis of the Sporothrix species in virulence and evolution, amid the largest sporotrichosis epidemic in Brazil. The identification of the genetic markers helps to enhance fungal surveillance and strengthen disease control.
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Plastic-degrading enzymes from landfills
Researchers identified and analysed the structure and predicted functions of potential plastic-degrading enzymes in collected landfills sample from around the world, in an effort to reduce plastic pollution.
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Immature platelet fraction offers clinical predictor for enhanced platelet recovery in patients with dengue fever
Immature platelet fraction (IPF) is recognized as a marker for thrombopoiesis, but a new study indicates that IPF% can be utilized as a predictor of platelet increase in patients with dengue infection.
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Research uncovers new strategy to reduce tissue damage from flesh-eating bacteria
A new study reveals a novel approach to mitigating tissue damage caused by Streptococcus pyogenes, the flesh-eating bacterium responsible for severe infections such as necrotizing fasciitis.
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Add some spice: Curcumin helps treat Mycobacterium abscessus
Researchers have found that adding curcumin boosts the efficacy of bedaquiline, an antimycobacterial used to treat tuberculosis, in combating M. abscessus infections. Curcumin is the compound that gives turmeric its characteristic bright orange color.
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Helicobacter pylori treatment practices in the Asia-Pacific region
Researchers conducted an online survey of clinicians in the Asia-Pacific region to investigate treatment policies for H. pylori and confirmed that there is a growing consensus of the importance of primary and secondary prevention against H. pylori.
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Metagenomic analysis of tick-borne viruses in Inner Mongolia
A new study maps the landscape of TBVs in Inner Mongolia, but also highlights the potential spillover risk of TBVs. These findings underscore the urgent need for One Health strategies for monitoring emerging TBVs at the tick-human-livestock interface in northern China.
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From order to chaos: Understanding the principles behind collective motion in bacteria
A new study has revealed how bacterial swarms transition from organized movement to chaotic flow. Combining large-scale experiments, computer modeling, and mathematical analysis, the team uncovered intermediate states that emerge between order and turbulence.