All Asia & Oceania articles – Page 22
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Epstein-Barr virus worsens ulcerative colitis by triggering macrophage pyroptosis through glycolysis
The study shows that EBV infection activates pyroptosis in intestinal macrophages by upregulating glycolysis. This process leads to the release of pro-inflammatory cytokines, which further damage the intestinal barrier and worsen colitis symptoms.
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Genetic resistance factors and antimicrobial resistance phenotypes in methicillin-resistant Staphylococcus aureus isolates of animals and humans
A new study identified three functional protein families in MRSA, through sequencing, that confer extensive antibiotic resistance independent of the known antibiotic resistance determinants, mecA and mecC.
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The key role of soil micro-food web complexity in agricultural productivity
Soils inoculated with micro-food webs have significantly higher levels of total nitrogen (TN), total phosphorus (TP), microbial biomass, and plant nitrogen and phosphorus compared to the control and untreated (unsterilized) soil, a new study shows.
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CeSPIACE: A broad-spectrum peptide inhibitor against variable SARS-CoV-2 spikes
CeSPIACE, a small remodified peptide, is able to block the binding of ACE2 receptor and the spike protein on SARS-CoV-2 and its variants. Hence, the cheap and simple peptide could treat COVID-19 infection and prevent reinfection after exposure of the virus.
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Bacteria key to solar-powered method to convert sewage sludge into green hydrogen and animal feed
Scientists have developed an innovative solar-powered method to transform sewage sludge — a by-product of wastewater treatment — into green hydrogen for clean energy and single-cell protein for animal feed.
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Scientists explain energy transfer mechanism in chloroplasts and its evolution
A recent study by Chinese scientists has revealed the intricate molecular machinery driving energy exchange within chloroplasts, shedding light on a key event in the evolution of plant life.
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Food systems, climate change, and air pollution: Unveiling the interactions and solutions
A recent review delves into the complex relationships among food systems, climate change, and air pollution, highlighting the need for sustainable strategies to address these interconnected global challenges.
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‘Overlooked’ scrub typhus may affect 1 in 10 in rural India
A study of over 32,000 people living in Tamil Nadu, India, suggests scrub typhus infection may affect up to 10% of rural populations annually and is a leading yet under-recognised cause of hospitalisations for fever across India.
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Study reveals complex interaction between plants and root microbiota in nutrient utilization
The root microbiota has a profound impact on plant growth and development, health, and adaptability to the environment. So, do the plants also have effects on the root microbiota, and if so, how do the two interact with each other?
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Clove oil yields new Pickering emulsion formulation with enhanced antibacterial properties
Researchers developed a sustainable Pickering emulsion using carbon quantum dots (CQDs), promising solid particles for food applications, derived from clove essential oil residue. They found that CQDs with 40% ethanol demonstrated the highest emulsifying efficacy.
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Multi-dose vaccines administered in the same site boost immune response
New research suggests that receiving multiple doses of a vaccine in the same limb leads to faster antibody development, an important strategy for providing immunity as quickly as possible during a pandemic or disease outbreak.
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Circadian rhythms in tea plant microbiomes shed light on nutrient cycling
A groundbreaking study has uncovered a fascinating connection between the circadian rhythms of tea plants and the microbial communities in their rhizosphere, providing new insights into nutrient cycling.
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New discovery and grant to accelerate Strep A vaccine efforts
With a large sum of research funding and multinational contributions, the world’s only Strep A human challenge model will be used to resolve logistical issues and speed up the development of a successful Strep A vaccine.
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Novel enzyme found in gut bacteria could revolutionize prebiotic research
Researchers have discovered a new β-galactosidase enzyme in a human gut bacterium that breaks down and synthesizes previously unexplored glycans, which have prebiotic capabilities to improve gut health.
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Dermatophytes adaptation to the human host exemplified by Microsporum canis
Through comparative genomic analyses, researchers investigated the evolutionary mechanisms that underpin gene expansions to enable dermatophytes, such as Microsporum canis to transition from animal to human hosts.
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Bacteria and minerals work together to detoxify arsenic in contaminated soils
New research shows that the interaction between arsenic-oxidizing bacteria and goethite, a common Fe mineral, significantly accelerates the conversion of arsenic from its highly toxic form, arsenite [As(III)], into the less harmful arsenate [As(V)].
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Purified immunoglobulin F(ab′) 2 prevents lethal staphylococcal enterotoxin B intoxication in mice and rhesus monkeys
Purified F(ab′)2 fragments are an effective antidote to lethal SEB doses in mice and rhesus monkeys, and therefore might be a favorable candidate for treating patients with severe SEB intoxication, a new study suggests.
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Transcription factor PoMbp1 promotes the growth of Pleurotus ostreatus by regulating polysaccharide utilisation
A study investigating the growth and development of Pleurotus ostreatus has found that PoMbp1 contains an APSES domain and localizes to the nucleus, indicating it belongs to the fungal-specific APSES transcription factors family.
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Antimicrobial resistance in soil bacteria without the use of antibiotics
Overuse of antibiotics is currently the primary reason for the rise of antimicrobial resistance (AMR), but researchers have shown that AMR can be found in soil bacterial communities due to microbial interactions too, driven by a species of predatory bacteria.
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siRNA-AGO2 complex inhibits bacterial gene translation: a novel therapeutic strategy for superbug infection
Scientists have demonstrated that exosomes can serve as delivery vehicles to introduce AGO2-loaded siRNA into the cytoplasm of bacteria, and in turn down-regulated gene expression of the mRNA that shares sequence complementarity to the siRNA.