All Bacteriophages articles
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NewsA viral ‘loose cannon’ enzyme helps phages shut down bacterial defenses
Scientists have found how phages, viruses that infect bacteria, orchestrate an explosion of protein modifications inside host cells that helps them evade the bacteria’s immune systems.
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NewsFrom local waterways to future therapies: Inspiring the next generation of scientists through phage discovery
Coventry University welcomed students from schools across the West Midlands for an immersive outreach experience focused on bacteria, viruses, AMR, and the potential of bacteriophages as a future tool in combating antibiotic-resistant infections.
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NewsEngineered macrophages gain enhanced bacteria-targeting ability
A novel membrane interface engineering strategy enables immune cells to specifically recognize, capture and eliminate pathogenic bacteria without genetic modification.
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NewsThinking beyond antibiotics in the treatment of urinary tract infections
A promising new study combines phage therapy (PT) with fecal microbiota transplantation (FMT) to treat recurrent urinary tract infections.
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NewsNew framework to reveal how microbial modulators can work alongside agricultural practices to boost plant performance
Scientists have proposed a new framework for understanding how microbes, soil fauna, viruses and compounds in the soil can be used alongside agricultural practices to reshape the native plant microbiome and boost plant performance.
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NewsResearchers find CRISPR-Cas coordinates layered bacterial defense network
A new study reveals that CRISPR-Cas plays a broader role in bacterial immunity. Rather than acting alone like a solitary sniper shooting at phages, it also serves as a central command center, directing a network of diverse innate immune systems.
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NewsScientists find hidden individuality in viral infections
An international team of researchers developed a new way to uncover hidden differences in how viruses infect and destroy individual microbial cells—solving a biological puzzle that has persisted for more than 80 years.
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NewsClinical trial aims to break the cycle of recurrent urinary tract infections with bacteria’s natural enemies
Researchers’ data-driven microbiological and phage therapy approaches may help move phage therapy beyond case-by-case experimental use toward a strategy that is predictable, measurable and clinically interpretable.
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NewsThe family tree of viruses just grew – and it paves the way for a new approach to agricultural research
Researchers have discovered that a group of viruses known to infect an agriculturally important plant pathogen has remained genetically stable for an astonishing four decades. The work also led to the classification and naming of the group of phages.
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NewsResearchers use friendly viruses to tackle inflammatory bowel disease
A research team has developed a targeted approach to treating inflammatory bowel disease (IBD) using bacteriophages, viruses that infect specific bacteria, to disarm harmful microbes without disrupting the broader gut ecosystem.
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NewsViruses under stress: how viral shells change shape as they dry out
New research explores the structural dynamics and conformational changes of bacteriophage MS2 capsids under conditions of dehydration.
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NewsRNA barcoding approach reveals previously unknown virus-host relationships
Researchers have uncovered previously unknown relationships between bacteriophages and their bacterial hosts. They found a previously unreported group of bacterial hosts for the well-studied bacteriophage P1 and examine how subtle changes in viral structure influence which microbes a phage can target.
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NewsMolecular anchors on gut phages may open new avenues for therapeutic development
A new study has identified phage surface proteins acting as molecular anchors. These proteins confer phages with the ability to attach to human cells. Using genetic engineering, the researchers transferred these adhesion proteins onto the surface of another phage that otherwise lacked this ability.
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NewsScientists probe antiviral molecules in bacteria that target bacteriophages
Researchers have examined the antiviral molecule daunorubicin, produced by Streptomycetes, and decoded its mode of operation against viruses. They now describe this mechanism, which primarily targets a specific group of viruses – namely bacteriophages.
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NewsThe future of phage therapy will be decided by more than science alone
As antimicrobial resistance accelerates worldwide, leading experts gather in Valencia to address the scientific, regulatory, manufacturing and clinical challenges that will determine whether phage therapy becomes a routine healthcare solution.
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NewsGladstone launches Center for PhAIge Therapy to harness AI in the fight against drug-resistant infections
Gladstone Institutes has received funding to establish the Center for PhAIge Therapy, a research center that will develop new phage-based treatments for antibiotic-resistant bacterial infections. The five-year grant makes Gladstone one of three institutions across the country selected to lead this coordinated effort.
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NewsProtection for newborns: New treatment aims to prevent meningitis without antibiotics
One of the leading pathogens responsible for meningitis cases in newborn babies is the K1 form of the E. coli bacterium. Now, researchers have developed a triple-pronged approach that seeks to prevent transmission to newborns.
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NewsEstablishing a regulatory framework for phage therapy in China
A new study summarizes the current regulatory frameworks for phage therapy in Western countries and China, and proposes a pathway for establishing a regulatory framework that enables safe and effective clinical application of phage therapy in China.
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NewsResearchers advance phage therapy in fight against antimicrobial resistance
Scientists have uncovered how Mycobacterium abscessus can evade bacteriophage therapy, and demonstrated a combination strategy to overcome this resistance, offering a pathway towards more effective and durable treatments.
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NewsResearchers uncover three families of ‘sponge’ proteins deployed by phages
Using an innovative research approach that combines artificial intelligence with experimental biology, researchers have uncovered new families of sponge proteins in phage genomes that disrupt immune communication in bacteria.