All Cancer Microbiology articles – Page 3
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NewsGut microbes rewrite the rules of cancer immunotherapy
A review synthesizes growing evidence showing that commensal microbes enhance anti-tumor immunity by producing immune-active metabolites, remodeling the tumor microenvironment, and activating key immune cells such as dendritic cells and cytotoxic T cells.
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NewsChemically ‘stapled’ peptides used to target difficult-to-treat cancers
Researchers have developed a new technology that uses bacteria to build, chemically stabilise, and test millions of potential drug molecules inside living cells. The bacteria produce vast libraries of peptide molecules, and chemically stabilise them into defined shapes while they are being tested inside the cell.
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NewsCell-free DNA offers early warning for bloodstream infections in kids with leukemia
Researchers show that microbial cell-free DNA sequencing can predict bloodstream infections in children with leukemia days before the symptoms appear. Plasma microbial cell-free DNA sequencing (mcfDNA-Seq) offer a potential approach to protecting vulnerable patients by allowing treatment to start before the patient gets sick.
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NewsBiomarkers indicating higher liver cancer risk in chronic hepatitis B patients identified
Researchers have identified Hepatitis B RNA serum levels as a biomarker that more accurately stratifies risk of liver cancer in individuals who have been functionally cured of chronic hepatitis B.
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NewsHPV vaccination provides “sustained protection” against cervical cancer
Human papillomavirus (HPV) vaccination is associated with a significantly reduced risk of invasive cervical cancer, with no indication of waning protection up to 18 years after vaccination, finds a study.
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NewsResearchers engineer bacteria capable of consuming tumours from the inside out
A research team is developing a novel tool to treat cancer by engineering hungry bacteria to literally eat tumours from the inside out. They added a gene to the organism from a related bacterium that can better tolerate oxygen and found a way to activate the oxygen-resistant gene at just the right time.
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NewsNewly discovered virus linked to colorectal cancer
Researchers have discovered a previously undescribed virus in a common gut bacterium, Bacteroides fragilis. The virus appears more frequently in patients with colorectal cancer.
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NewsHow bacteria may promote breast cancer
Researchers have discovered how certain pathogenic bacteria in gut and breast tissue can promote breast cancer development and progression by hijacking a key metabolic enzyme known as spermine oxidase (SMOX).
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NewsScientists develop first-of-its-kind antibody to block Epstein Barr virus
Using mice with human antibody genes, scientists have developed new genetically human monoclonal antibodies that prevent two key antigens on the surface of the Epstein Barr virus (EBV) from binding to and entering human immune cells.
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NewsA yeast enzyme helps human cells overcome mitochondrial defects
An international team has experimentally uncoupled nucleotide synthesis from mitochondrial activity using ScURA, a yeast-derived genetic tool now available to the research community that will enable new explorations of cellular metabolism.
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NewsRhododendron-derived drugs now made by bacteria
Bioengineered E. coli bacteria can now produce a group of compounds with anticancer, anti-HIV, antidiabetic and anti-inflammatory activities. The compounds, orsellinic acid-derived meroterpenoids, are produced by Rhododendron species.
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NewsImmunity against common virus leveraged against pancreatic cancer
Researchers have discovered a promising new treatment approach for pancreatic cancer. The approach leverages the body’s natural immune response to cytomegalovirus (CMV), a common but typically harmless virus that most people are infected with at some point in their lives.
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NewsBasic research on Listeria bacteria leads to unique cancer therapy
After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, researchers have discovered a way to turn the bacteria into a potent booster of the immune system — and a potential weapon against cancer.
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NewsHPV cancer vaccine slows tumor growth, extends survival in preclinical model
Scientists discovered that systematically changing the orientation and placement of a single cancer-targeting peptide can lead to formulations that supercharge the immune system’s ability to attack HPV-driven tumors.
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NewsVirus-based therapy boosts anti-cancer immune responses to brain cancer
A study has shown that a single injection of an oncolytic virus—a genetically modified virus that selectively infects and destroys cancer cells—can recruit immune cells to penetrate and persist deep within brain tumors.
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NewsTesting menstrual blood for HPV could be “robust alternative” to cervical screening
Testing menstrual blood for human papillomavirus (HPV) could be a “robust alternative or replacement” for current cervical cancer screening by a clinician, finds a study. The researchers say using menstrual blood for HPV testing is convenient and non-invasive.
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NewsYeast cells can be used for rapid testing of cancer immunotherapy
An international research team has developed a new yeast-based biotechnological platform that makes it possible to test and understand advanced cancer treatments much faster and cheaper than before. It can reduce development time for new types of cancer immunotherapy from months to days or weeks.
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News A fungus living in our body can make melanoma more aggressive
A study has for the first time established the mechanism by means of which the Candida albicans fungus makes melanoma more aggressive. It activates several signalling pathways in the melanoma cells, creating an environment that helps to reprogram angiogenesis and metabolism.
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NewsHigh consumption of ultraprocessed foods may be linked to cancer survivors’ risk of death
Cancer survivors who consumed higher amounts of ultraprocessed foods as part of their diet had a significantly increased risk of both all-cause and cancer-specific death, a new study shows.
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NewsStudy suggests far fewer cervical cancer screenings are needed for HPV‑vaccinated women
In a modeling study of women vaccinated against human papillomavirus (HPV), researchers found that cervical cancer screening could be done far less often than current recommendations without compromising health benefits.