Scientists implicate a novel cellular protein in hepatitis A infection

(Left) Liver cells infected with hepatitis A. The white arrows show areas with dying liver cells surrounded by inflammatory cells generated by the immune response to the virus. (Right) Liver cells infected with hepatitis A and lacking PDAP1.

Source: Shirasaki et al. (2024)

Viruses have thrived in humans for tens of thousands of years, evolving to take advantage of the machinery of cells to replicate and survive inside us. Some can slip past our defenses and invade without even causing symptoms.

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