All University of North Carolina articles
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News
Public health experts put out call for collaboration in antiviral therapeutics development coalition
Establishing a global therapeutics development coalition is a vital next step to invigorate the therapeutics pipeline and drive advocacy for increased investment and coordination of end-to-end therapeutics development, say a group of public health experts.
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Mutations of the spike gene do not predict the severity of variants of SARS-CoV-2
The two recent and prevalent strains of the virus that cause COVID-19 are not significantly better than their predecessor Omicron at evading immune responses and causing infections despite having a higher number of mutations.
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U-M lands $6.5 million center to study links between Great Lakes algal blooms, human health
Great Lakes researchers at the University of Michigan have been awarded a $6.5 million, five-year federal grant to host a center for the study of links between climate change, harmful algal blooms and human health.
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Oral nucleoside antiviral is progressing toward future pandemic preparedness
Oral obeldesivir has been shown to reduce disease severity in mice infected with one of several different coronaviruses, including SARS-CoV-2 (which causes COVID-19), SARS-CoV and MERS-CoV.
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Bioinformatics professor discovers surprising evolutionary pattern in landmark yeast study
A new study challenges accepted frameworks within which yeast evolution is studied and provide access to an incredibly rich yeast analysis dataset that could have major implications for future evolutionary biology and bioinformatics research.
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Probiotics in kombucha mimic fasting and reduce fat stores in worms
In a new study, researchers found that the microbes in kombucha tea make changes to fat metabolism in the intestines of a model worm species that are similar to the effects of fasting.
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New trial highlights incremental progress towards a cure for HIV-1
A new clinical trial suggests that a combination of the drug vorinostat and immunotherapy can coax HIV-infected cells out of latency and attack them.
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Antibiotic is cost-saving treatment for reducing maternal sepsis in developing countries
New findings suggest that giving an oral dose of azithromycin to pregnant women who deliver vaginally is a cost-saving treatment for reducing maternal sepsis, death or infection in developing countries.
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Malaria parasites resistant to treatment and detection emerge in Ethiopia
Genomic surveillance by scientists has revealed mutations in malaria-causing parasites that will complicate efforts to eradicate the disease in Africa.
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Diazotrophs show nitrogen fixation hotspots in Atlantic seaweed communities
A new study examining nitrogen fixation among diazotrophs – microorganisms that can convert nitrogen into usable form for other plants and animals – has found significant hotspots in sargassum communities.
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New research shows HIV can lie dormant in the brain
Researchers in the UNC School of Medicine extracted living brain tissue to conclude that specialized immune cells in the brain can harbour latent but replication-competent HIV.
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Bacterial species teams with Streptococcus to boost tooth decay
Researchers have discovered that a bacterial species called Selenomonas sputigena can have a major role in causing tooth decay.
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Careers
Unearthing the secrets of living rocks
Working on a NASA-CSA project was a dream come true - and 13 years on, I’ve travelled the world unravelling the secret of contemporary microbialites.
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Ultrasound helps break bacterial barriers in chronic treatment-resistant wounds
Researchers have developed a new strategy combining palmitoleic acid, gentamicin, and non-invasive ultrasound to improve drug-delivery into chronic wound infections.
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‘Hangry’ bacteria pump out toxins, unlike their identical but well-fed colleagues
New study shows that genetically identical cells within a bacterial community have different functions, with some members behaving more docile and others producing the very toxins that make us ill.
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Scientists find two separate reservoirs of latent HIV in patients
Scientists have shown that, addition to HIV’s ability to lay dormant in the blood/lymphoid system, the virus may also lay dormant in the central nervous system, delineating another challenge in creating a cure.
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Potential drug takes aim at emerging Chikungunya virus
Researchers are developing what could become the first-ever treatment against the debilitating joint pain that can last months or years after becoming infected with the emerging Chikungunya virus.