All Cancer Microbiology articles
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NewsSugar amplifies damage done to gut health by antibiotics
Eating sweets while taking antibiotics may worsen the harm done by the drugs to the normal community of bacteria in the gut, a new study has found. The study of hospitalized cancer patients found an additional 21% reduction in the variety of helpful bacterial species present for every 100 grams of sugar consumed in the 48 hours before treatment.
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NewsPneumonia can reveal undiagnosed blood cancer
Severe pneumococcal disease requiring hospitalization, most commonly pneumonia, can be a sign of previously undiagnosed blood cancer and immunodeficiency in adult patients, according to a study.
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News Distinct gut microbiome patterns found in 5 cancer groups and in early-onset cancers
Researchers have discovered distinct gut microbiome patterns in adults 50 or younger with colorectal and breast cancers compared with those diagnosed later in life — one of several findings from an analysis of stool samples from 1,364 patients with cancer across cancer types, stages and treatments.
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NewsGut microbiome emerges as a potential partner in precision cancer therapy
A new editorial examines how the human microbiome may influence cancer development, treatment response and emerging precision-oncology strategies.
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NewsOral chiral nanozyme protects the heart during chemotherapy by reshaping the gut-heart axis
A chirality-engineered nanozyme restores gut microbiota and host metabolism to prevent doxorubicin-induced cardiotoxicity without compromising anticancer efficacy.
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NewsLab tackles antibiotic resistance across multiple fronts in new trio of studies
To defeat multidrug-resistant superbugs, bacterial defenses must be confronted wherever they may emerge, from basic genetic mutations in a laboratory, to complex real-world transmission in hospital rooms. A new trio of studies demonstrates how an integrated approach might yet expose and overcome these diverse survival mechanisms.
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NewsCan probiotics help T cells fight solid tumors more effectively?
Transferred T cells often have difficulty reaching tumors and overcoming the strongly immunosuppressive environment surrounding cancer cells. Researchers have combined therapeutic T cells with engineered probiotics, physically attaching the bacteria to the surface of T cells to create a hybrid system called T-FOLactis.
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NewsFecal microbiota transplantation may improve immunotherapy-related colitis
Targeting the gut microbiome with fecal microbiota transplantation may help cancer patients with immunotherapy-related colitis avoid the need for steroids and other immune-suppressing treatments, according to researchers.
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NewsGut, airway and tumor microbes emerge as promising predictors of immunotherapy response in lung cancer
A comprehensive review systematically evaluates the microbiome’s role in lung cancer immunotherapy. Authors synthesized evidence covering microbial communities in the oral cavity, airways, lung tumors and gut, and their connections to treatment efficacy and immune‑related adverse events.
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NewsFusobacterium nucleatum drives immunosuppression and metastasis in TNBC
A new study identifies Fusobacterium nucleatum, a Gram-negative anaerobic bacterium associated with several cancers, as a key driver of tryptophan metabolic reprogramming, immunosuppression and lung metastasis in triple-negative breast cancer.
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NewsHelicobacter pylori exposure may be linked to more than 1 in 5 bowel cancer cases worldwide
Exposure to the stomach microbe Helicobacter pylori may be associated with more than 1 in 5 cases of bowel cancer worldwide, suggests an exploratory risk attribution study - and those born in more recent decades may be more at risk of the disease after exposure.
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NewsBacteria can make testosterone. What could that mean for prostate cancer?
Scientists have identified an unexpected participant in androgen chemistry: a bacterium from the human urinary tract that can convert the steroid precursor DHEA into testosterone under laboratory conditions. It reveals a previously unknown microbial route to a hormone that is central to prostate biology.
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NewsThe push to understand and treat HPV
Karl Munger is helping to lead an effort at Tufts University and Tufts Medicine that brings research scientists together with clinicians to save lives through improved HPV care and research.
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NewsBacterial nanoplatform targets spleen to reprogram immune cells and prevent cancer recurrence
Researchers have announced the development of an engineered nanoplatform named t-SMC, which precisely targets the spleen to reverse splenic myelopoiesis toward an antitumoral immune phenotype.
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NewsDiet quality linked to upper gastrointestinal cancer, with anxiety and depression playing a mediating role
A new study indicates that poor dietary quality - particularly insufficient intake of fruits, vegetables, legumes, and dairy - is significantly associated with both psychological distress and cancer diagnosis.
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NewsMouth and gut microbes could help detect gastrointestinal cancers
Researchers report that by analyzing the make-up of oral microbes it may be possible to detect signals associated with stomach and colorectal cancer. These findings could lead to the development of new, less-invasive screening tests for gastrointestinal cancers.
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NewsBacteria found in lung tumors may boost immune response to cancer
New preclinical study shows bacteria in lung tumors may boost the activation of innate immune cells in the presence of a common vitamin metabolite.
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NewsNext-gen mRNA therapeutics get a new delivery vehicle
Researchers have developed a novel way of delivering circular RNA into cells, paving way for long-lasting mRNA-based therapeutics including cancer vaccines and obesity treatments.
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NewsDevelopment of dual-action compounds to fight cancer and infections
Researchers have developed new hybrid compounds that simultaneously reduce the viability of aggressive cancer cells and inhibit the growth of certain bacteria and fungi.
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NewsGut-pancreas immune crosstalk may offer new therapeutic strategies for pancreatic cancer
A new study reports that immune responses produced in lymph nodes shared by the liver, pancreas and intestine shape T-cell tolerance. This cross-organ immune rewiring increases T-cell infiltration into pancreatic tumors, pointing to potential new approaches for hard-to-treat pancreatic cancers.