All Cancer Microbiology articles
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Gut bacteria can reveal colorectal cancer
Researchers identified all human gut bacteria to a level of detail that uncovers the physiological importance of the different microbial subgroups. This inventory was then used to detect the presence of colorectal cancer according to the bacteria present in simple stool samples.
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Colibactin-producing E. coli linked to higher colorectal cancer risk in FAP patients
Researchers have found that patients carrying colibactin-producing Escherichia coli in their colon polyps were more than three times as likely to have a history of colorectal cancer compared to those without the bacterium.
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Epstein-Barr virus protein EBNA1 upregulates oncogenes in cervical cancer cells
New findings suggest that increased expression levels of Derlin1 and PSMD10 genes in HeLa cells by the EBV-EBNA1 might induce cancer cell survival and accelerates the development of cervical cancer (CC).
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1 in 3 US adults unaware of connection between HPV and cancers
The human papillomavirus (HPV) can cause six types of cancer, yet new analysis shows that most people are unaware of the connection between HPV and all of these cancers.
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A microbial DNA signature differentiates two types of cancer in the liver
Researchers have identified a microbial DNA signature in blood plasma that reliably differentiates primary liver cancer from colorectal cancer that has spread to the liver (metastatic colorectal cancer).
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‘Essentiality’ scan reveals microbe’s ‘must-have’ list
Researchers have spent years taking apart one of the world’s simplest microbes, Mycoplasma pneumoniae, piece by piece, and created a detailed list of what molecular parts the living cell can and cannot do without.
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Why killer cells can lapse into ‘exhausted’ CD8+ T cells that no longer can stem disease
In a detailed study of exhausted T cell subsets researchers show that a transcriptional repressor called Gfi1 is a key regulator of the subset formation of exhausted CD8+ T cells and may offer a key to reducing exhaustion.
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AUN bacteria herald an immune-independent breakthrough
A joint research team has developed a groundbreaking immune-independent bacterial cancer therapy using a novel microbial consortium called AUN (阿吽), composed of two naturally occurring bacteria: a tumor-resident microbe and photosynthetic bacterium.
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Scientists discover how leukemia virus stays hidden in the body
A research team has discovered how the human T-cell leukemia virus type 1 (HTLV-1) silently persists in the body. Their findings identify a previously unknown genetic “silencer” element that keeps the virus in a dormant, undetectable state.
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Immunoglobulin replacement therapy shows no reduction in serious infections for patients with CLL
In patients with chronic lymphocytic leukemia (CLL), regular treatment with immunoglobulin replacement therapy was not associated with a reduced risk of serious infections requiring hospitalization, according to a study published in Blood Advances.
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Gut microbiome transplants show promise for boosting cancer immunotherapy
A comprehensive new review examines the effects of transferring healthy gut bacteria to cancer patients receiving immune checkpoint inhibitors (ICIs).
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Engineers take a closer look at how a plant virus primes the immune system to fight cancer
Scientists took a closer look at how the cowpea mosaic virus (CPMV), unlike other plant viruses, is uniquely effective at activating the body’s immune system to recognize and attack cancer cells.
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Can a compound produced by deep-sea bacteria treat cancer?
Investigators purified a long-chain sugar molecule, or exopolysaccharide, from deep-sea bacteria and demonstrated that it triggers pyroptosis—an inflammatory form of programmed cell death—to inhibit tumor growth.
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Fermented stevia leaf extract has potential as anticancer treatment, researchers find
Stevia may provide more benefits than as a zero-calorie sugar substitute. When fermented with bacteria isolated from banana leaves, stevia extract kills off pancreatic cancer cells but doesn’t harm healthy kidney cells, according to a research team.
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Tumor-targeting fluorescent bacteria illuminate cancer for precision surgery
Researchers have developed a next-generation intraoperative imaging platform using engineered beneficial bacteria that emit fluorescence specifically at tumor sites. This illuminates tumors like a neon sign during surgery, enabling more precise resection and reducing risk of recurrence.
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How tumor microbes shape cancer: New insights into microbial diversity in the tumor microenvironment
Intratumoral microbiota—the microbial populations residing within solid tumors—have emerged as pivotal components of the tumor microenvironment (TME), influencing tumor initiation, progression, and therapeutic outcomes.
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Michael Danquah named Fellow of Royal Society of Biology
Michael Danquah, a professor in the Department of Chemical and Biomolecular Engineering and the associate dean for academic and student affairs at the University of Tennessee at Knoxville, has been elected as a Fellow of the Royal Society of Biology.
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Penicillium hispanicum yields discovery of new bianthrones and chlorinated bianthrones with cytotoxic activity against cancer cells
A new study reports the discovery of three novel racemic bianthrones from Penicillium hispanicum LA032 using HSQC-based DeepSAT, as well as their cytotoxic evaluation and mechanistic investigation through network pharmacology.
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Cohort data from Denmark show real-world evidence of stable protection against HPV-related cervical cancer
Denmark has been offering free vaccination against human papillomavirus (HPV) to girls since 2008. New data show vaccination has effectively reduced infections with cancerogenic HPV 16/18 types covered by the vaccine, indicating population immunity.
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Gut microbes key to understanding how exercise boosts cancer immunity
A new study shows how exercise improves cancer outcomes and enhances response to immunotherapy in mice by reshaping the gut microbiome. These benefits are driven by a specific compound called formate, which is produced by gut bacteria in exercised mice.