All Cancer Microbiology articles
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NewsBacteria found in lung tumors may boost immune response to cancer
New preclinical study shows bacteria in lung tumors may boost the activation of innate immune cells in the presence of a common vitamin metabolite.
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NewsNext-gen mRNA therapeutics get a new delivery vehicle
Researchers have developed a novel way of delivering circular RNA into cells, paving way for long-lasting mRNA-based therapeutics including cancer vaccines and obesity treatments.
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NewsDevelopment of dual-action compounds to fight cancer and infections
Researchers have developed new hybrid compounds that simultaneously reduce the viability of aggressive cancer cells and inhibit the growth of certain bacteria and fungi.
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NewsGut-pancreas immune crosstalk may offer new therapeutic strategies for pancreatic cancer
A new study reports that immune responses produced in lymph nodes shared by the liver, pancreas and intestine shape T-cell tolerance. This cross-organ immune rewiring increases T-cell infiltration into pancreatic tumors, pointing to potential new approaches for hard-to-treat pancreatic cancers.
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NewsCells use a little-known molecule to protect themselves from iron overload
New research shows that cells rely on an unexpected protector against elevated iron levels: small molecules called polyamines. These small molecules act like storage lockers for iron, safely holding the metal in a non-reactive state until cells need it.
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NewsNovel AI model accurately detects key gene mutations and predicts biomarkers across 32 cancer types
Researchers have developed a novel AI model capable of predicting cancer subtypes, specific genetic mutations, and survival outcomes across 32 different cancers.
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NewsWorld’s first oral microbiome-based nanomedicine to supercharge anti-cancer immunity
Researchers have successfully developed the world’s first oral, microbiome-based nanomedicine which enhances the ability of immune cells to attack cancer cells.
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NewsTumor-like tissue environments could hold clues to curing HIV
The tissue microenvironments surrounding HIV-infected immune cells look a lot like those surrounding cancerous tumors, reports a new study. The findings help explain why HIV has been so difficult to cure.
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NewsThe ‘windows’ that set genotoxic bacteria on a track towards colorectal cancer
Scientists have identified potential ‘windows of opportunity’ that can provide routes for some pathogenic strains of E coli to cause mutations that ultimately lead to colorectal cancers.
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NewsHidden microbial ecosystems inside tumors reveal new frontiers for cancer treatment
Far from being sterile, tumors host complex communities of bacteria, fungi, and viruses that actively influence disease progression, immune responses, and treatment outcomes. A review highlights how these microbial populations function as key regulators of tumor immunity.
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NewsIntratumoral Fusobacterium as a prognostic and predictive biomarker in resectable colorectal cancer
Research supports the use of Fusobacterium as a prognostic and predictive biomarker in patients with resectable stage I–III CRC. Its presence was associated with more aggressive disease, a weaker immune response, and limited benefit from adjuvant chemotherapy.
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NewsReshaping the gut microbiome can boost chemotherapy delivery to tumors
A common antibiotic reshaped gut bacteria in preclinical models, significantly reducing liver clearance and doubling how long chemotherapy remained in circulation to reach tumors.
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NewsThe amino acid arginine helps the body fight tumors and viral infections
Scientists have discovered that an arginine-deficient diet impacts the immune system by stalling the production of the MHC-1 protein, which alerts the immune system to dangers such as a mutating cell or an invading virus.
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NewsBugs as drugs: Engineered gut bacteria show promise against pancreatic cancer
Cancer immunotherapies have transformed treatment for many cancers, but pancreatic cancer remains especially difficult to treat. One major reason is that pancreatic tumors often create a “cold” tumor microenvironment, where the tumor prevents immune cells from mounting a strong attack. In a new study published in Science ...
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NewsResearchers link gut microbe to cancer-fighting immune response
A new study is the first to show metabolites produced by certain bacteria in the gut can positively impact the body’s immune response to cancer.
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NewsGenetically engineered Bifidobacterium shows potential for oral delivery of cancer vaccines
A novel oral vaccine platform using genetically engineered Bifidobacterium could enhance anti-tumor immunity. In an exploratory phase I clinical study, the vaccine was well tolerated and generated immunologic and clinical findings that warrant further investigation.
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NewsMicrobiome and cancer: From passive bystanders to active players
A special issue reviews how microbiome science and cancer biology can converge as an integrated front for precision oncology. Articles span topics from hepatocellular carcinoma and colorectal cancer to gastric cancer and pancreatic ductal adenocarcinoma.
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NewsResearchers call for increased screening for parasitic disease linked to HIV and cervical cancer risk
New research has highlighted the need to test millions of women and girls for female genital schistosomiasis (FGS), a neglected disease that can increase the risk of chronic illness, HIV and cervical cancer.
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NewsGene-editing tool can unearth new cancer treatments from fungi
Engineers have developed a gene-editing tool built specifically for fungi, unlocking a hidden library of molecules—including some with early anti-cancer promise—from one of biology’s most overlooked kingdoms.
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NewsThe respiratory microbiota in lung cancer: from dysbiosis and immunomodulatory networks to therapeutic opportunities
A comprehensive review reveals that dysbiosis of the respiratory microbiota drives lung cancer through four integrated pathways: oncogenic signaling, epigenetic/metabolic reprogramming, and chronic immune dysregulation.